A5073204688- Vitamin D Research Studies
- Systemic Lupus Erythematosus Research
- Diabetes Management and Research
- Parathyroid Disorders and Treatments
- Pancreatic function and diabetes
- Dialysis and Renal Disease Management
- Pancreatitis Pathology and Treatment
- Chronic Kidney Disease and Diabetes
- Complement system in diseases
- Diabetes Treatment and Management
- Renal Diseases and Glomerulopathies
- Adipokines, Inflammation, and Metabolic Diseases
- Pharmacological Effects and Toxicity Studies
- Liver Diseases and Immunity
- Muscle and Compartmental Disorders
- Gout, Hyperuricemia, Uric Acid
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Dietary Effects on Health
- Bariatric Surgery and Outcomes
- Lanthanide and Transition Metal Complexes
- Advanced Glycation End Products research
- Acute Kidney Injury Research
- Vasculitis and related conditions
- Retinal Diseases and Treatments
- Pharmacology and Obesity Treatment
Cairo University
2018-2025
Cairo University hospitals
2022-2023
European Association for the Study of Diabetes
2023
Serum 25-hydroxyvitamin D (25(OH)D) negatively correlates with serum phosphorus level of stage 3a-5 chronic kidney disease (CKD) patients. So far, no explanation has been provided for this negative association.To confirm association and determine if relationship is mediated through other known co-morbid factors.One hundred (57 male 43 female) pre-dialysis CKD patients were selected. Estimated glomerular filtration rate (eGFR), calcium (Ca), (P), 25(OH)D, parathyroid hormone (PTH), intact...
Background Patients with diabetic kidney disease (DKD) are at increased risk to develop post-contrast acute injury (AKI). Diabetic patients under dipeptidyl peptidase 4 inhibitors (DPP4Is) experience a lower propensity AKI. We speculated that linagliptin as single agent or in combination allopurinol may reduce the incidence of AKI stage 3–5 chronic (CKD) underlying DKD.Methods Out 951 DKD eligible for this study, 800 accepted sign informed consent. They were randomly allocated equal groups...
Background: Current international guidelines recommend a pre-Ramadan risk assessment for people with diabetes (PwDM) who plan on fasting during the Holy month. However, comprehensive assessment-based recommendation management of PwDM intending to fast is still controversial. Therefore, Arabic Association Study Diabetes and Metabolism (AASD) developed this consensus provide further insights into stratification in Ramadan. Methods: The present was based three-step modified Delphi method....
Diabetes mellitus and depression are comorbidities that can be caused by each other. Brain-derived neurotrophic factor (BDNF) functions as a neuronal growth factor. It maintains the functional integrity of nervous system.
Low serum 25 hydroxyvitamin D (25 OH D) is common among chronic kidney disease (CKD) patients. This cross-sectional study looking for the different factors associated with pre-dialysis CKD. 1624 adult stage 3-5 CKD patients were studied beside 200 normal control subjects. All candidates tested body mass index (BMI), estimated glomerular filtration rate (eGFR), calcium (Ca), phosphorus (P), parathormone (PTH), D, albumin, and uric acid (UA), urine albumin/creatinine ratio (ACR). Multivariate...
One of the most significant consequences systemic lupus erythematosus (SLE) is nephritis (LN). Visfatin, an adipokine that significantly expressed in visceral fat and a marker endothelial dysfunction chronic kidney disease, has multiple proinflammatory actions. We aimed to evaluate state serum visfatin SLE patients detect its possible correlation with disease's activity effects on affection. Fifty active LN, 50 inactive lupus, healthy people had their levels tested. Chemical immunological...
Systemic lupus erythematosus (SLE) is an inflammatory autoimmune disease characterized by production of a number antinuclear antibodies. Podocyte injury important feature and can be detected several markers including podocalyxin. We aimed to evaluate the impact SLE on urinary levels podocalyxin determine its relationship renal biopsy, proteinuria, activity in nephritis (LN) patients. Sixty individuals were recruited; 30 patients with LN as well healthy volunteers they subjected full history,...
Systemic lupus erythematosus (SLE) is a multisystem chronic autoimmune disease characterized by tissue inflammation. There increased cardiovascular mortality in cases with SLE. Endothelial dysfunction an early stage of atherosclerosis, which can be reversed early. We aimed to study noninvasive assessment endothelial Egyptian patients Three hundred individuals were recruited; 100 SLE nephritis (LN), free LN as well healthy volunteers. The vascular function was evaluated through...
Abstract Background and Aims There is uncertainty regarding the best indication, device type, frequency, length of time, kind replacement fluid, criteria for ceasing therapeutic plasma exchange (TPE) various disorders. TPE an intrusive technique that has potential to save lives, but it also a risk unfavorable outcomes complications, necessitating close supervision by professional teams. In intensive care unit (ICU), there are three categories indications TPE: (1) absolute, well-established,...
Serum 25-hydroxyvitamin D (25(OH)D) negatively correlates with serum phosphorus level of stage 3a-5 chronic kidney disease (CKD) patients. So far, no explanation has been provided for this negative association. To confirm association and determine if relationship is mediated through other known co-morbid factors. One hundred (57 male 43 female) pre-dialysis CKD patients were selected. Estimated glomerular filtration rate (eGFR), calcium (Ca), (P), 25(OH)D, parathyroid hormone (PTH), intact...
Diabetic nephropathy (DN) is the most common cause of end-stage renal disease. Urinary pigment epithelium-derived factor (PEDF) has also been shown to suppress expression fibrogenic, pro-inflammatory, and angiogenic factors, thus contributing pathological changes in early DN. We aimed study role urinary PEDF as a biomarker for detection chronic kidney disease progression patients with type 2 diabetes mellitus (T2DM). Sixty T2DM were recruited addition 20 nondiabetic healthy volunteers. using...
Abstract Introduction Systemic lupus erythematosus is an autoimmune multisystem disease; renal affection one of its most common manifestations. The effect environmental factors on nephritis flares not fully understood. Methods This a retrospective study that included 200 patients with flares. All had confirmed diagnosis histopathological examination. Lupus were defined by either (1) nephritic flare: as increased proteinuria or serum creatinine concentration; abnormal urinary sediment...