Vascular calcification has detrimental consequences on chronic kidney disease (CKD) patients, yet its pathogenesis is not fully understood. Fibroblast growth factor-23 (FGF-23) involved in the regulation of mineral metabolism which may turn affect vascular calcification. Data relationship between FGF-23 and peripheral calcification, using conventional radiographs, are conflicting, less known about relation to aortic We conducted this study investigate a standard haemodialysis setting.The...

Fibroblast growth factor-23 (FGF-23) has been linked to vascular calcification, ventricular hypertrophy and mortality in chronic kidney disease (CKD), although these links may not be direct independent. Similar grave outcomes are associated with inflammation oxidative stress CKD. Recently, accumulating evidence components of phosphate homeostasis stress. The interaction between the triad inflammation, FGF-23 cardiovascular is underinvestigated.We studied 65 patients stage 5 CKD on...

Insulin resistance (IR) is very common among chronic kidney disease (CKD) patients. Disturbance in mineral and bone metabolism (MBD) seems to play a role the pathogenesis of insulin resistance. Fibroblast growth factor-23 (FGF23) evolving as most important link between MBD many pathologic sequences CKD. The aim was evaluate IR pre-dialysis CKD patients looking for possible association A total 100 stage 3–5 were selected beside 20 normal control subjects. Homeostatic model assessment...

Systemic inflammation is a recognized feature in chronic kidney disease (CKD). The role of systemic the pathogenesis vascular calcification was recently settled. FGF23 accused as direct stimulus inflammation. This finding explains strong association to and increased mortality among CKD.

Serum 25-hydroxyvitamin D (25(OH)D) negatively correlates with serum phosphorus level of stage 3a-5 chronic kidney disease (CKD) patients. So far, no explanation has been provided for this negative association.To confirm association and determine if relationship is mediated through other known co-morbid factors.One hundred (57 male 43 female) pre-dialysis CKD patients were selected. Estimated glomerular filtration rate (eGFR), calcium (Ca), (P), 25(OH)D, parathyroid hormone (PTH), intact...

<b><i>Background:</i></b> Recent studies have demonstrated negative associations of serum uric acid (SUA) with 25 hydroxy vitamin D (25 [OH] vit D) among CKD patients. <b><i>Objective:</i></b> The aim the study was to look for impact hypouricemic therapy using allopurinol on level (OH) in <b><i>Cases and Methods:</i></b> Seventy-two stage 3–5 patients were selected this study. Patients SUA above 7 mg/dL allocated (group...

Background Patients with diabetic kidney disease (DKD) are at increased risk to develop post-contrast acute injury (AKI). Diabetic patients under dipeptidyl peptidase 4 inhibitors (DPP4Is) experience a lower propensity AKI. We speculated that linagliptin as single agent or in combination allopurinol may reduce the incidence of AKI stage 3–5 chronic (CKD) underlying DKD.Methods Out 951 DKD eligible for this study, 800 accepted sign informed consent. They were randomly allocated equal groups...

Many of the mineral metabolite abnormalities encountered in chronic kidney disease (CKD) patients were found also associated with acute injury (AKI). In last decade, sclerostin was to intimately affect bone metabolism CKD patients. Nothing is known about AKI. We looked for serum level AKI comparison normal control subjects and if there an impact on metabolic derangement, endothelial function or clinical outcome. This a cross sectional case observational study 219 cases (group I) beside age...

The non-calcium-based phosphate binder sevelamer hydrochloride was developed to provide chronic kidney disease patients with a polymer capable of managing hyperphosphatemia without an increase in the calcium load. These beneficial effects were postulated as mechanism decreased progression vascular calcification observed such compounds. Our objective investigate effect low-dose against carbonate binders on coronary artery score ( CCS) and fibroblast growth factor 23 FGF23) level receiving...

Many of the mineral metabolite abnormalities encountered in chronic kidney disease (CKD) patients were found also associated with acute injury (AKI). In last decade, sclerostin was to intimately affect bone metabolism CKD patients. Nothing is known about AKI. We looked for serum level AKI comparison normal control subjects and if there an impact on metabolic derangement, endothelial function or clinical outcome. This a cross sectional case observational study 219 cases (group I) beside age...

Abstract: This study aims to determine the presence of Newcastle Disease (ND) virus antibody titers and percentage monocyte cells in native chickens (Gallus domesticus) at a farm Permata Village, Tilongkabila Subdistrict, Bone Bolango Regency. The method used this research is qualitative descriptive. Antibody titer data were obtained from results HI (Haemagglutination Inhibition) test, while was determined using 10% Giemsa staining with parallel track counting.The showed that out 50 samples,...

Low serum 25 hydroxyvitamin D (25 OH D) is common among chronic kidney disease (CKD) patients. This cross-sectional study looking for the different factors associated with pre-dialysis CKD. 1624 adult stage 3-5 CKD patients were studied beside 200 normal control subjects. All candidates tested body mass index (BMI), estimated glomerular filtration rate (eGFR), calcium (Ca), phosphorus (P), parathormone (PTH), D, albumin, and uric acid (UA), urine albumin/creatinine ratio (ACR). Multivariate...

The impact of hepatitis virus infection on arterial calcification (AC) was not studied.To study the prevalence, severity and distribution AC in incident hemodialysis patients with B C viral infection.172 stage 5 CKD adults (98 male 74 female) were included; 58 them seronegative for both (SN group), 48 positive (HBV group) 66 (HCV group). Beside histopathology obtained samples, all these cases examined body mass index (BMI), serum calcium (Ca), phosphorus (P), alkaline phosphatase (AP),...

The impact of hepatitis virus infection on arterial calcification (AC) was not studied. To study the prevalence, severity and distribution AC in incident hemodialysis patients with B C viral infection. 172 stage 5 CKD adults (98 male 74 female) were included; 58 them seronegative for both (SN group), 48 positive (HBV group) 66 (HCV group). Beside histopathology obtained samples, all these cases examined body mass index (BMI), serum calcium (Ca), phosphorus (P), alkaline phosphatase (AP),...

Background: Despite the high prevalence of diabetes mellitus in Egypt, real and epidemiology gestational (GDM) Upper Egypt is still lacking. Objective: This study aims to determine risk factors GDM among pregnant women evaluate foetal maternal outcomes this disease. Methods: prospective cohort was conducted between July 2014 2018. Universal screening for all attending primary health care clinics done using Diabetes Pregnancy Study Group India (DIPSI) criteria. Those with were followed up...

Background: Loin pain is frequently not associated with any urinary abnormality.Musculoskeletal abnormalities are uncommon as alternative cause of flank pain.Osteomalacia the ribs was infrequently encountered pain.Vitamin D deficiently has been reported common problem worldwide special predilection to Middle East area.Objective: In this study, we looked for vitamin deficiency in patients tenderness over tips lowermost ribs.Cases and methods: Out 783 presenting unilateral or bilateral a...

<b><i>Introduction:</i></b> Arterial calcification (AC) is a common complication in chronic kidney disease (CKD) patients that starts to develop before these need renal replacement therapy. In patients, can involve tunica intima or media. This study has looked for the prevalence, severity, and distribution of arterial wall incident hemodialysis through intraoperative biopsy obtained during creation arteriovenous vascular access hemodialysis....