A5033360798- Liver Disease Diagnosis and Treatment
- Diet and metabolism studies
- Diabetes Treatment and Management
- Adipokines, Inflammation, and Metabolic Diseases
- Vitamin D Research Studies
- Autophagy in Disease and Therapy
- Hepatitis C virus research
- Diet, Metabolism, and Disease
- Pancreatitis Pathology and Treatment
- Cardiovascular Health and Disease Prevention
- Advanced Glycation End Products research
- Bariatric Surgery and Outcomes
- Cardiovascular Disease and Adiposity
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diabetic Foot Ulcer Assessment and Management
- MicroRNA in disease regulation
- Diabetes and associated disorders
- Wound Healing and Treatments
- Bee Products Chemical Analysis
- Dialysis and Renal Disease Management
- Circular RNAs in diseases
- Biomarkers in Disease Mechanisms
- Laser Applications in Dentistry and Medicine
- Muscle and Compartmental Disorders
- Diabetes Management and Education
Cairo University
2015-2025
Ain Shams University
2019-2024
Diabetes Australia
2021
The wound-healing process in diabetic foot is affected by pro and anti-inflammatory markers, any disruption the inflammatory reaction interferes with tissue homeostasis, leading to chronic non-wound healing. This study aimed determine diagnostic value effect of CRP, IL-6, TNF, HbA1c on initiation progression ulcers. ELISA was used quantify 205 patients diabetes, 105 were free. prevalence also evaluated. area under curve (AUC) calculated using receiver operating characteristic (ROC) analyze...
Purpose: Few data are available on the positive impact of photo-biomodulation (PBM) using low-level laser therapy as a complementary treatment for improving cognitive function and optimizing hemoglobin (Hb) level oxygen carrying capacity in anemic elderly patients consequently quality-of-life. The present study aimed to evaluate new, safe, easy therapeutic approach improve Alzheimer's disease-related symptoms that interfere with whole life activities social interaction patients. Patients...
Insulin resistance (IR) is very common among chronic kidney disease (CKD) patients. Disturbance in mineral and bone metabolism (MBD) seems to play a role the pathogenesis of insulin resistance. Fibroblast growth factor-23 (FGF23) evolving as most important link between MBD many pathologic sequences CKD. The aim was evaluate IR pre-dialysis CKD patients looking for possible association A total 100 stage 3–5 were selected beside 20 normal control subjects. Homeostatic model assessment...
Transcription factor 7-like 2 (TCF7L2) variants are known risk factors of type diabetes (T2DM).However, this association is not consistent among different populations. The current study aimed at investigating the relationship between rs 7903146, 12255372 TCF7L2 and susceptibility to T2DM metabolic parameters in a cohort Egyptian diabetic patients. This case control included 60 patients matched unrelated healthy controls. Genotyping was performed by using Real Time-PCR. frequency genotypes,...
Spleen may be enlarged in patients with metabolic syndrome (MS). Many factors that are encountered MS were incriminated as etiology of the splenomegaly. The aim this study was to assess spleen longitudinal diameter (SLD) and investigate possible affecting size. included 60 30 healthy controls. Assessment full medical history, anthropometric measurements, abdominal ultrasound identify SLD hepatic steatosis carried out. Liver enzymes, lipid profile, interleukin-10 (IL-10) measured. Fatty liver...
The main aim of this study was to assess the expression level circulating long non-coding RNA maternally expressed gene 3 (lncRNA-MEG3), microRNA (miR-125a-5P), chemokine C-X-C motif ligand13 (CXCL13), and nuclear factor kappa-light-chain-enhancer activated B cells (NF-kB) in immune thrombocytopenia (ITP) cases its relation disease severity treatment response. This case-control included 45 patients newly diagnosed as ITP healthy subjects. We assessed complete blood count, antinuclear...
There is less data regarding the changes in body mass index (BMI) after treating hepatitis C virus (HCV) patients with new direct-acting antiviral agents (DAAs). This study aimed to assess BMI chronic HCV treated DAAs Egypt and explore other factors influencing this change.The of who received therapy one Egypt's specialized viral treatment centers were retrospectively analyzed. In addition routine clinical laboratory workup, weight during monitored was calculated. Viral load measured at 12...
Poor glycemic control is a risk factor for micro and macrovascular complications of diabetes. The aim this study was to assess the prevalence factors related suboptimal diabetes in group patients with type 2 mellitus (T2DM). This cross-sectional descriptive conducted Al Qassim region, Saudi Arabia. Two hundred T2DM were enrolled. Demographic, social, self-care behavior data collected. A thorough clinical evaluation done. Glycated hemoglobin, lipid, kidney profile results recorded....
The wound-healing process in diabetic foot is affected by pro and anti-inflammatory markers, any disruption the inflammatory reaction interferes with tissue homeostasis, leading to chronic non-wound healing. This study aimed determine diagnostic value effect of CRP, IL-6, TNF, HbA1c on initiation progression ulcers. ELISA was used quantify 205 patients diabetes, 105 were free. prevalence also evaluated. area under curve (AUC) calculated using receiver operating characteristic (ROC) analyze...
Type 2 diabetes (T2DM) represents a major risk factor for atherosclerosis that is the underlying cause of most cardiovascular diseases. Identifying reliable predictive biomarkers are needed to improve long-term outcome in diabetic patients. Autophagy plays pivotal role pathogenesis atherosclerosis. Beclin1 key regulatory protein autophagy and has been localized human atherosclerotic lesions. However, relation serum level patients with not clarified yet.To assess relationship between carotid...
To determine the association between serum osteocalcin and carotid intima media thickness (CIMT) in a group of post-menopausal females with type 2 diabetes (T2DM).This cross-sectional study enrolled 75 postmenopausal women T2DM 40 age matched healthy females. Age, body mass index, blood pressure were recorded for all subjects. Laboratory tests including fasting glucose (FBG), glycated hemoglobin (HbA1c) lipid profile measured. Serum was measured using ELISA. Bone mineral density (BMD) by...
Background: Obesity, insulin resistance, and diabetes are major risk factors for nonalcoholic fatty liver disease (NAFLD). This study aims to evaluate the association between different grades of NAFLD abdominal subcutaneous fat thickness with homeostasis model assessment resistance (HOMA-IR). Methods: In this pilot study, 59 obese nondiabetic participants were enrolled. Total cholesterol, Hb A1c , HOMA-IR measured. Abdominal in midline just below xiphoid process front left lobe (LSFT)...
Abstract Aims Early detection of retinal microangiopathy in patients with prediabetes may reduce diabetic retinopathy complications. The aim this study was to assess early macular vascular changes prediabetics before development over diabetes using OCTA and fundus photography. Methods In cross-sectional study, 66 prediabetic individuals normal controls underwent clinical, laboratory, photography evaluation followed by imaging examine for the foveal avascular zone, area capillary...
Obesity is associated with metabolic and cardiovascular co-morbidities. It important to determine the factors derangement in obesity. Autophagy plays a major role pathogenesis of syndrome. MicroRNA-30a targets beclin1, main regulator autophagy.We assess circulating microRNA-30a serum beclin1 women metabolically unhealthy obesity (MUO), healthy (MHO) non-obese control their relationship different clinical variables obesity.This cross-sectional study included 34 MHO, MUO, 20 women. Blood...
Abstract Background Thyroid imaging reporting and data system (TI-RADS) is assessment of risk stratification thyroid nodules, using a score. A novel ACR (American College Radiology) TI-RADS has been recently suggested by American Radiology. But, the utility in for lesion needs further evaluation. Aim Of this study was to evaluate classification discriminating benign from other lesions as detected fine needle aspiration cytology (FNAC). Methods This retrospective included all patients...
Cyclophilin D (CypD) is a mitochondrial matrix protein involved in liver steatosis and fibrosis vitro. However, the role of CypD development fatty humans has not been determined. To measure serum level patients with type 2 diabetes (T2DM) nonalcoholic disease (NAFLD) to assess its relation presence hepatic this group patients. In cross-sectional study, 30 NAFLD were compared without age- sex-matched healthy subjects. Abdominal ultrasound was used diagnose NAFLD. Serum measured using ELISA....
To evaluate vascular endothelial growth factor (VEGF) levels in hepatocellular carcinoma patients before and after transcatheter arterial chemoembolization (TACE) percutaneous ethanol injection (PEI) its relation to treatment response. A total of 40 with unrespectable hepatocelluar were assessed clinically. Twenty suitable be treated by TACE, while other 20 PEI. Serum VEGF measured 1 month each procedure ELISA. Response was according Union Internationale Contre le Cancer evaluation criteria...