Mohamed‐Naguib Wifi

ORCID: 0000-0002-3403-7106
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About
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Research Areas
  • Liver Disease Diagnosis and Treatment
  • COVID-19 Clinical Research Studies
  • Liver Disease and Transplantation
  • Hepatitis C virus research
  • Long-Term Effects of COVID-19
  • COVID-19 and healthcare impacts
  • Pancreatic and Hepatic Oncology Research
  • Hepatitis B Virus Studies
  • Diabetes and associated disorders
  • Gastrointestinal disorders and treatments
  • Gastrointestinal Bleeding Diagnosis and Treatment
  • Dermatological and COVID-19 studies
  • Pancreatitis Pathology and Treatment
  • Nutrition and Health in Aging
  • Diet, Metabolism, and Disease
  • Eosinophilic Disorders and Syndromes
  • Liver Diseases and Immunity
  • Pediatric Hepatobiliary Diseases and Treatments
  • Circular RNAs in diseases
  • Global Healthcare and Medical Tourism
  • Immune Response and Inflammation
  • Diabetic Foot Ulcer Assessment and Management
  • SARS-CoV-2 and COVID-19 Research
  • Cancer-related molecular mechanisms research
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms

Cairo University
2017-2024

Zagazig University
2017

Assiut University
2017

Beni-Suef University
2017

<title>Abstract</title> <bold>Background</bold> Long-standing diabetes mellitus (DM) can lead to macrovascular and microvascular complications including autonomic neuropathy, which disrupts gut motility. Gastroparesis (GP) is defined as delayed gastric emptying of solids (with or without liquids) in the absence any mechanical obstruction. The gold standard test for diagnosis gastroparesis scintigraphy (GS) using a solid meal. poses diagnostic therapeutic challenges, significantly impact...

10.21203/rs.3.rs-6067249/v1 preprint EN 2025-04-10

AIMTo evaluate the accuracy of elastography score combined to strain ratio in diagnosis solid pancreatic lesions (SPL). METHODSA total 172 patients with SPL identified by endoscopic 5962

10.3748/wjg.v23.i32.5962 article EN cc-by-nc World Journal of Gastroenterology 2017-01-01

Toll-like receptors (TLRs) are innate immune that mediate the inflammatory response in diabetes mellitus (DM). The aim of this study is to evaluate association TLR2 and TLR9 gene polymorphism patients with type 2 DM (T2DM) diabetic foot (DF). included 90 subjects divided into group I (30 T2DM DF), II no evidence III (normal control subjects). (1350 T/C, rs3804100) (1237 rs5743836) genotyping was performed by polymerase chain reaction–restriction fragment length (PCR-RFLP) technique for all...

10.1097/md.0000000000006760 article EN cc-by-nc Medicine 2017-04-01

Although the frequent respiratory affection in COVID-19, it is well established that could be presented with a wide variation of gastrointestinal symptoms; however, effect on pancreas remains unclear.We report case female patient, who was diagnosed COVID-19 infection. A week later, patient developed an attack acute pancreatitis. Other causes pancreatitis were excluded. Therefore, this attributed to SARS-COV2 infection.The raises awareness about possibility COVID-19. Also emphasize importance...

10.1186/s43162-021-00039-y article EN cc-by The Egyptian Journal of Internal Medicine 2021-03-01

Liver metastases might not be detected by computed tomography (CT) and magnetic resonance imaging (MRI) due to their small size, but they can EUS. Furthermore, EUS-FNA has a significant impact on improving the diagnostic accuracy of The purpose this study was assess feasibility EUS in detection occult hepatic focal lesions at time primary tumor staging, seen CT or MRI.This prospective included 730 patients who underwent for staging sampling gastrointestinal, pancreatic, thoracic malignancy....

10.4103/eus-d-20-00178 article EN Endoscopic Ultrasound 2021-01-01

There is less data regarding the changes in body mass index (BMI) after treating hepatitis C virus (HCV) patients with new direct-acting antiviral agents (DAAs). This study aimed to assess BMI chronic HCV treated DAAs Egypt and explore other factors influencing this change.The of who received therapy one Egypt's specialized viral treatment centers were retrospectively analyzed. In addition routine clinical laboratory workup, weight during monitored was calculated. Viral load measured at 12...

10.5152/tjg.2019.18514 article EN The Turkish Journal of Gastroenterology 2019-08-15

Cyclophilin D (CypD) is a mitochondrial matrix protein involved in liver steatosis and fibrosis vitro. However, the role of CypD development fatty humans has not been determined. To measure serum level patients with type 2 diabetes (T2DM) nonalcoholic disease (NAFLD) to assess its relation presence hepatic this group patients. In cross-sectional study, 30 NAFLD were compared without age- sex-matched healthy subjects. Abdominal ultrasound was used diagnose NAFLD. Serum measured using ELISA....

10.2147/ijgm.s322986 article EN cc-by-nc International Journal of General Medicine 2021-08-01

The current study aimed to evaluate the efficacy of different DAAs regimens in treatment chronic hepatitis C (CHC) Egyptian patients who failed achieve SVR after their with SOF-based regimens.This was a retrospective observational multicenter that included CHC cure on were re-treated using regimen and allocated according national guidelines for C. Primary outcome assess SVR12 rate among prior non-responders retreatment second course DAAs.Our 172 [age: 51.2 ± 11.3, 58.7% men]. Included...

10.1016/j.ijid.2020.04.022 article EN cc-by-nc-nd International Journal of Infectious Diseases 2020-04-20

Abstract Background Esophagitis dissecans superficialis (EDS) is a rare desquamative esophageal condition with wide range of presentations, from asymptomatic cases to those severe, life-threatening symptoms. EDS has strong association several conditions, such as autoimmune diseases, smoking, and certain medications, although it can also occur without any apparent cause (idiopathic). Diagnosis involves comprehensive approach, including clinical assessment (history examination), endoscopic...

10.1186/s43162-024-00345-1 article EN cc-by The Egyptian Journal of Internal Medicine 2024-08-09

Hepatitis C virus (HCV) is a common disease in Egypt with high socioeconomic burden and extra-hepatic manifestations as QT prolongation, but previous studies included mainly patients advanced liver disease, so this study, we aimed to delineate the prevalence of prolongation early-stage HCV patients. The study 874 early cirrhosis; Child’s class A, 57 (6.5%) had prolonged interval corrected (QTc). There was significant higher proportion cirrhotic QTc group (31.6%) vs. normal (11.5%). 424.39 ±...

10.1186/s43044-019-0016-0 article EN cc-by The Egyptian Heart Journal 2019-09-06

Liver cirrhosis and hepatocellular carcinoma (HCC) are consequences of chronic hepatitis C virus (HCV) infection. HCC is one the fastest rising causes cancer-related mortality. This dismal prognosis related to late diagnosis with currently available screening methods. The aim our study was evaluate diagnostic power serum growth differentiation factor (GDF) 15 in detection its ability distinct from Egyptian patients. Ninety participants were included study; 30 patients HCV-cirrhosis,...

10.4103/ejim.ejim_39_18 article EN cc-by The Egyptian Journal of Internal Medicine 2019-03-01

Abstract Background Colonic Dieulafoy’s lesions (DLs) are an extremely rare cause of acute gastrointestinal bleeding. However, it could be presented from self-limiting, mild bleeding episodes up to recurrent, massive life-threatening hemorrhage. Case presentation We present a case 9-year-old female with recurrent attacks hematochezia. The colonoscopy showed actively at the rectosigmoid colon that was successfully managed endoscopically by application two hemoclips. Conclusion A prompt and...

10.1186/s43162-023-00231-2 article EN cc-by The Egyptian Journal of Internal Medicine 2023-06-26

Abstract Background COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the newly developed worldwide outbreak of disease with a high rate mortality especially among elderly and multiple co-morbid personnel. Asymptomatic COVID-19-infected patients are well-known source transmission infection. The risk exposure to secretions and/or feces hardly avoidable during endoscopic procedure; also, aerosol droplets take up an hour disperse, so...

10.1186/s43162-020-00029-6 article EN cc-by The Egyptian Journal of Internal Medicine 2020-11-25

Abstract The therapeutic usage of EUS is being developed. EUS-guided biliary drainage (EUSBD) a recognized viable replacement for percutaneous transhepatic (PTBD) in severe cases with the obstructive disease having ERCP failure due to cannulation or those surgically altered anatomies, such as hepatico-jejunal anastomosis following Billroth II reconstruction, Roux-en-Y limb, Whipple procedure, gastric bypass, inaccessible papilla because duodenal inflammatory structure.

10.1186/s43162-022-00151-7 article EN cc-by The Egyptian Journal of Internal Medicine 2022-08-04

Abstract Mallory–Weiss tear is a rare complication that could result following cardiopulmonary resuscitation, leading to vigorous upper gastrointestinal bleeding. We illustrate case of an 84-year-old male patient, admitted the hospital for investigation lung nodules and bilateral pleural effusion. The patient developed cardiac arrest during aspiration, resuscitation was done, which followed shortly by attack acute Urgent endoscopy revealed mucosal with submucosal oozing blood two large...

10.4103/azmj.azmj_55_21 article EN cc-by-nc-sa Al-Azhar Assiut Medical Journal 2021-07-01
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