- Liver Disease Diagnosis and Treatment
- Gallbladder and Bile Duct Disorders
- Gastrointestinal Bleeding Diagnosis and Treatment
- Pancreatic and Hepatic Oncology Research
- Long-Term Effects of COVID-19
- Gastric Cancer Management and Outcomes
- Hepatitis C virus research
- COVID-19 and Mental Health
- Dietary Effects on Health
- COVID-19 Clinical Research Studies
- Cancer-related molecular mechanisms research
- Genetic factors in colorectal cancer
- Cancer Cells and Metastasis
- Liver Disease and Transplantation
- Hepatocellular Carcinoma Treatment and Prognosis
- Pancreatitis Pathology and Treatment
- Epigenetics and DNA Methylation
- Global Health and Surgery
- Cancer-related Molecular Pathways
- Pediatric Hepatobiliary Diseases and Treatments
- Colorectal Cancer Screening and Detection
- Complement system in diseases
- Gastrointestinal disorders and treatments
- COVID-19 and healthcare impacts
- Hepatitis B Virus Studies
Zagazig University
2016-2025
Collaborative Group (United States)
2023
Umm al-Qura University
2022
GTx (United States)
2018
Assiut University
2014
Objectives The long-term consequences of COVID-19 infection on the gastrointestinal tract remain unclear. Here, we aimed to evaluate prevalence symptoms and post-COVID-19 disorders gut–brain interaction after hospitalisation for SARS-CoV-2 infection. Design GI-COVID-19 is a prospective, multicentre, controlled study. Patients with without diagnosis were evaluated hospital admission 1, 6 12 months post hospitalisation. Gastrointestinal symptoms, anxiety depression assessed using validated...
The eradication rate of Helicobacter pylori following the standard triple therapy is declining. This study was conducted to test whether addition Lactobacillus reuteri improves rates as well clinical and pathological aspects in H. infection.
INTRODUCTION: Gastrointestinal (GI) symptoms in coronavirus-19 disease (COVID-19) have been reported with great variability and without standardization. In hospitalized patients, we aimed to evaluate the prevalence of GI symptoms, factors associated their occurrence, variation at 1 month. METHODS: The GI-COVID-19 is a prospective, multicenter, controlled study. Patients COVID-19 diagnosis were recruited hospital admission asked for after month, using validated Symptom Rating Scale...
ABSTRACT Background The severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) pandemic has highlighted the potential exacerbation of gastrointestinal symptoms in patients with disorders gut‐brain interaction (DGBIs). However, distinct symptom trajectories and psychological burden post‐COVID‐19 DGBIs compared pre‐existing irritable bowel (IBS)/functional dyspepsia (FD) non‐DGBI controls remain poorly understood. Objectives To examine long‐term progression comorbidities DGBI, IBS/FD...
Introduction: Toxoplasma gondii is an intracellular protozoan that may disrupt the traditional cell barriers against cancer, allowing accumulation of oncogenic mutations over time. Our research aimed to explore relationship between T. infection and tumor development.
 Methodology: The anti-T. IgG IgM antibodies were tested for156 patients with tumors (51 breast 20 hepatoma, larynx carcinoma, squamous carcinoma bone, 16 lymphoma, 13 brain tumor, 4 bladder cancer 12 benign uterine tumor)...
Background. Depression and cognitive impairment are two common mental public health problems especially among elderly. In this study, we determined the prevalence of these their associations with sociodemographic factors hospitalized elderly in Egypt. To achieve this, 200 medical inpatients were included cross-sectional study. Methods. Comprehensive geriatric assessment was done for every participant. Sociodemographic variables assessed by interviews patients family members. Depressive...
Collaborative research consists of an equal partnership researchers from diverse backgrounds who pursue mutually interesting and beneficial questions to achieve a common purpose via the coordination activities sharing knowledge, competencies, resources, information, resulting in new scientific knowledge [1,2].Hence, collaboration could involve continuum organisational levels ranging individual institutions, organisations, or even communities different disciplines geographical locations...
BACKGROUND: Epithelial-mesenchymal transition (EMT) is one of the main events in colorectal cancer (CRC) spread. Snail-1 a zinc transcription factor that mediates EMT tumor cells probably by down-regulation E-cadherin and claudin-1. OBJECTIVES: To detect expression epithelia l markers (claudin-1 E-cadherin) mesenchymal (snail-1 vimentin) primary colon. Also, to select stage II patients high risk can benefit from postoperative adjuvant chemotherapy. METHODS: Reverse transcription-polymerase...
Abstract Papillary thyroid carcinoma (PTC) is considered the most prevalent malignancy. The association between Hashimoto’s thyroiditis (HT) and PTC still unclear. We aimed to examine clinicopathological impact of immunohistochemical staining FOXP3 Cytokeratin 19 in concomitant HT their correlation with patients' outcome survival. Eighty biopsies obtained from patients were immunostained by CK19.The treated radioactive iodine (I 131 ) followed up. CK19 expression detected 45% 80% studied...
Aim: Cryptosporidiosis causes colon dysplasia. This research aimed to evaluate the effect of a novel combination between artesunate and nitazoxanide on intensity infection resulting intestinal Materials & methods: Subjects were divided into five groups. Artesunate was used alone, then combined with nitazoxanide. Results: The highest efficacy in reducing oocyst shedding obtained from therapy (68.5, 75.9, 99%) after 7, 14 21 days. histopathology infected colonic mucosa showed marked...
Background: hepatitis C is an inflammatory liver disease caused by the infection (HCV), and without treatment, almost 50% will progress to cirrhosis. Hepatocellular carcinoma (HCC) most frequent type of primary cancer fourth leading cause cancer-related mortality. Aim study: objective this study was evaluate serum level vitronectin (VTN) compared AFP determine their role as diagnostic prognostic markers HCV-related diseases. Subject Methods: involved 52 HCV patients from which 26 were...
The current coronavirus disease 2019 (COVID-19) pandemic has affected routine endoscopy service across the gastroenterology community. This led to suspension of provision for elective cases.
Background and study aim Bile duct injuries are not infrequently seen during hepatobiliary surgery, particularly after liver transplantation cholecystectomy. The current aims to figure out the frequency of postcholecystectomy biliary (PCBI) role early versus late endoscopic retrograde cholangiopancreatography (ERCP) in their management. Patients methods Totally 960 cases operated by both laparoscopic open cholecystectomy were evaluated study. In total, 942 our institutes, ( n = 925) 17)...
Abstract The chance of getting colorectal cancer (CRC) is higher in people with chronic ulcerative colitis (UC). impact parasitic infections on UC underappreciated. purpose this study was to look into the effect intestinal protozoal dysplastic changes generated by UC. research included 152 adult patients histologically confirmed and healthy controls. Fecal samples were examined for presence parasites fecal calprotectin (FC). enzyme-linked immunosorbent assay measured serum anti-p53...