- Renal Transplantation Outcomes and Treatments
- Organ Transplantation Techniques and Outcomes
- Dialysis and Renal Disease Management
- Renal Diseases and Glomerulopathies
- Liver Disease Diagnosis and Treatment
- Chronic Kidney Disease and Diabetes
- Extracellular vesicles in disease
- Parasites and Host Interactions
- Hepatitis C virus research
- Muscle and Compartmental Disorders
- HIV/AIDS drug development and treatment
- Systemic Lupus Erythematosus Research
- Kidney Stones and Urolithiasis Treatments
- Renal and Vascular Pathologies
- MicroRNA in disease regulation
- Organ and Tissue Transplantation Research
- Metabolism, Diabetes, and Cancer
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Pregnancy and preeclampsia studies
- Tissue Engineering and Regenerative Medicine
- Mosquito-borne diseases and control
- Pharmacological Effects and Toxicity Studies
- Vitamin D Research Studies
- Research on Leishmaniasis Studies
- Pediatric Urology and Nephrology Studies
Cairo University
1995-2023
Cairo University hospitals
2022
Bio-products from stem/progenitor cells, such as extracellular vesicles, are likely a new promising approach for reprogramming resident cells in both acute and chronic kidney disease. Forty CKD patients stage III IV (eGFR 15-60 mg/ml) have been divided into two groups; twenty treatment group "A" matching placebo "B". Two doses of MSC-derived vesicles had administered to "A". Blood urea, serum creatinine, urinary albumin creatinine ratio (UACR) estimated glomerular filtration rate (eGFR) used...
To assess the impact of multiple access tracts during percutaneous nephrolithotomy (PCNL) on short- and midterm renal function, to determine risk factors predicting function deterioration and/or recoverability.Patients undergoing PCNL with punctures were prospectively enrolled. Preoperative evaluation included dimercaptosuccinic acid diethylenetriaminepentaacetic renography. Patients classified according baseline into patients normal (<1.4 mg/dL) serum creatinine (group A) elevated (≥1.4 B)....
Fibroblast growth factor-23 (FGF-23) has been linked to vascular calcification, ventricular hypertrophy and mortality in chronic kidney disease (CKD), although these links may not be direct independent. Similar grave outcomes are associated with inflammation oxidative stress CKD. Recently, accumulating evidence components of phosphate homeostasis stress. The interaction between the triad inflammation, FGF-23 cardiovascular is underinvestigated.We studied 65 patients stage 5 CKD on...
We studied serious renal disease in Egypt by registering all 155 patients coming to the nephrology service at University of Cairo during a period 62 days 1993. The presented with severe uremic symptoms. Admission creatinine and urea levels were high, 804 μmol/l 64 mmol/l. Fifteen percent died; 115 underwent dialysis. Sixty chronic failure; 53 acute failure, but 24 these later found have end-stage failure. Of 29 true 11 (38%) had pre-renal failure 7 (24%) postrenal Twenty-one followed up...
This prospective study reports the design and results obtained after EMPODaT project implementation. was funded by Tempus programme of European Commission with objective to implement a common postgraduate on organ donation transplantation (ODT) in six selected universities from Middle East/North Africa (MENA) countries (Egypt, Lebanon Morocco). The consortium, coordinated University Barcelona, included Spain, Germany, Sweden France. first phase perform an analysis current situation...
Tacrolimus (TAC) is the mainstay of immunosuppressive regimen for kidney transplantations. Its clinical use complex due to high inter-individual variations which can be partially attributed genetic at metabolizing enzymes CYP3A4 and CYP3A5. Two single nucleotide polymorphisms (SNPs), CYP3A4*22 CYP3A5*3, have been reported as important causes differences in pharmacokinetics that affect efficacy and/or toxicity TAC.Investigating effect CYP3A5*3 SNPs individually combination on TAC...
Abstract Introduction Systemic lupus erythematosus is an autoimmune multisystem disease; renal affection one of its most common manifestations. The effect environmental factors on nephritis flares not fully understood. Methods This a retrospective study that included 200 patients with flares. All had confirmed diagnosis histopathological examination. Lupus were defined by either (1) nephritic flare: as increased proteinuria or serum creatinine concentration; abnormal urinary sediment...