Shuji Fujita

ORCID: 0000-0003-0127-0777
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About
Contact & Profiles
Research Areas
  • Cryospheric studies and observations
  • Winter Sports Injuries and Performance
  • Geology and Paleoclimatology Research
  • Climate change and permafrost
  • Polar Research and Ecology
  • MicroRNA in disease regulation
  • Arctic and Antarctic ice dynamics
  • Chromatin Remodeling and Cancer
  • Cancer Mechanisms and Therapy
  • Landslides and related hazards
  • Methane Hydrates and Related Phenomena
  • Enzyme-mediated dye degradation
  • Phytochemicals and Antioxidant Activities
  • Food Quality and Safety Studies
  • Postharvest Quality and Shelf Life Management
  • Carbohydrate Chemistry and Synthesis
  • Glycosylation and Glycoproteins Research
  • Biofuel production and bioconversion
  • Chemical Synthesis and Analysis
  • Isotope Analysis in Ecology
  • Fermentation and Sensory Analysis
  • Polyamine Metabolism and Applications
  • Atmospheric and Environmental Gas Dynamics
  • Spectroscopy and Chemometric Analyses
  • RNA modifications and cancer

National Institute of Polar Research
2015-2024

The Graduate University for Advanced Studies, SOKENDAI
2014-2024

Nippon Soken (Japan)
2024

Research Organization of Information and Systems
2011-2023

Saga University
2001-2016

Nakamura Gakuen University
2014

Tokyo University of Agriculture and Technology
2013

Fujita Health University
2010

Tokyo University of Science
2010

Gifu University
2010

Abstract. We present Bedmap2, a new suite of gridded products describing surface elevation, ice-thickness and the seafloor subglacial bed elevation Antarctic south 60° S. derived these using data from variety sources, including many substantial surveys completed since original Bedmap compilation (Bedmap1) in 2001. In particular, Bedmap2 ice thickness grid is made 25 million measurements, over two orders magnitude more than were used Bedmap1. most parts Antarctica landscape visible much...

10.5194/tc-7-375-2013 article EN cc-by ˜The œcryosphere 2013-02-28

Abstract. The EPICA (European Project for Ice Coring in Antarctica) Dome C drilling East Antarctica has now been completed to a depth of 3260 m, at only few meters above bedrock. Here we present the new EDC3 chronology, which is based on use 1) snow accumulation and mechanical flow model, 2) set independent age markers along core. These are obtained by pattern matching recorded parameters either absolutely dated paleoclimatic records, or insolation variations. We show that this time scale...

10.5194/cp-3-485-2007 article EN cc-by-nc-sa Climate of the past 2007-08-17

A two‐frequency radio echo sounding experiment was carried out at Dome Fuji, the second highest dome in East Antarctica, and along a 1150‐km‐long traverse line from to coast. The goal determine dominant causes of internal reflections investigate their possible changes with depth ranges regions. From (60 MHz 179 MHz) responses various sites, we distinguished four zones. Each zones is characterized by cause reflection as follows. In “P D ” zone, dielectric permittivity are mainly due density...

10.1029/1999jb900034 article EN Journal of Geophysical Research Atmospheres 1999-06-10

Abstract. The recovery of a 1.5 million yr long ice core from Antarctica represents keystone our understanding Quaternary climate, the progression glaciation over this time period and role greenhouse gas cycles in progression. Here we tackle question where such may still be found Antarctic sheet. We can show that old is most likely to exist plateau area East sheet (EAIS) without stratigraphic disturbance should able recovered after careful pre-site selection studies. Based on simple heat...

10.5194/cp-9-2489-2013 article EN cc-by Climate of the past 2013-11-05

Abstract. One-dimensional (1-D) ice flow models are used to construct the age scales at Dome C and Fuji drilling sites (East Antarctica). The poorly constrained glaciological parameters each site recovered by fitting independent markers identified within core. We reconstruct past accumulation rates, that larger than those modelled using classical vapour saturation pressure relationship during glacial periods up a factor 1.5. During Early Holocene, changes in reconstructed not linearly...

10.5194/cp-3-243-2007 article EN cc-by-nc-sa Climate of the past 2007-06-01

Abstract Purpose: To better understand microRNA miR-21 function in carcinogenesis, we analyzed expression patterns different stages of colorectal cancer development using situ hybridization (ISH). Experimental Design: Locked nucleic acid (LNA)/DNA probes and a biotin-free tyramide signal amplification system were used ISH analyses miRNA expression. Conditions for specific detection determined human cell lines miR-21–expressing lentiviral vectors. Expression was 39 surgically excised tumors...

10.1158/1078-0432.ccr-08-3257 article EN Clinical Cancer Research 2009-06-15

Abstract. Fabric (distribution of crystallographic orientations) along the full NEEM ice core, Greenland was measured in field by an automatic texture analyzer every 10 m, from 33 m down to 2461 depth. The fabric evolves a slightly anisotropic at top, toward strong single maximum about 2300 which is typical deformation pattern mostly driven uniaxial compression and simple shearing. A sharp increase strengthening rate observed Holocene Wisconsin (HW) climatic transition. From model we...

10.5194/tc-8-1129-2014 article EN cc-by ˜The œcryosphere 2014-07-01

Abstract. One of the key components this research has been mapping Antarctic bed topography and ice thickness parameters that are crucial for modelling flow hence predicting future loss ensuing sea level rise. Supported by Scientific Committee on Research (SCAR), Bedmap3 Action Group aims not only to produce new gridded maps international scientific community, but also standardize make available all geophysical survey data points used in producing Bedmap products. Here, we document latest...

10.5194/essd-15-2695-2023 article EN cc-by Earth system science data 2023-07-17

Polyphenol oxidase (EC 1.10.3.1, PPO) in the pulp of banana (Musa sapientum L.) was purified to 636-fold with a recovery 3.0%, using dopamine as substrate. The enzyme exhibited clear single band on polyacrylamide gel electrophoresis (PAGE) and sodium dodecyl sulfate (SDS)-PAGE. molecular weight estimated be about 41000 42000 by filtration SDS-PAGE, respectively. quickly oxidized dopamine, its K(m) value for 2.8 mM. optimum pH at 6.5, activity stable range 5-11 5 degrees C 48 h. had an...

10.1021/jf991037+ article EN Journal of Agricultural and Food Chemistry 2000-06-09

To investigate the viscosity structure of ice sheets induced by crystal orientation fabric (COF), we carried out a multipolarization plane and dual‐frequency radar survey in East Antarctica. Radar surveys were done along 670‐km‐long flow line from Dome Fuji toward coast two transverse lines 300‐km 20‐km length, respectively. The echoes highly dependent on polarization for depths between about 40 60% thickness lower reaches convergent sector approaching outlet glacier. When was perpendicular...

10.1029/2003jb002425 article EN Journal of Geophysical Research Atmospheres 2003-10-01

Abstract Crystal-orientation fabric (COF) has a large influence on ice-sheet flow. Earlier radar studies have shown that COF-based birefringence occurs within ice sheets. Radio-wave scattering in polar results from changing physical properties of permittivity and conductivity arise differing values density, acidity COF. We present an improved mathematical model can handle all these phenomena together. use this matrix-based to study the two-way propagation depolarized radio waves scatter at...

10.3189/172756506781828548 article EN Journal of Glaciology 2006-01-01

The chromatin remodeling complex SWI/SNF is an important epigenetic regulator that includes one Brm or BRG1 molecule as catalytic subunit. and do not function identically, so this can regulate gene expression either positively negatively, depending on the promoter to which it recruited. Notably, attenuation due posttranscription suppression occurs often in human tumor cells, event contributes their oncogenic potential. Here, we report 3'-untranslated region of mRNA has two sites are...

10.1158/0008-5472.can-10-2345 article EN Cancer Research 2010-12-29

Abstract. To better understand the spatio-temporal variability of glaciological environment in Dronning Maud Land (DML), East Antarctica, a 2800-km-long Japanese-Swedish traverse was carried out. The route includes ice divides between two ice-coring sites at Dome Fuji and EPICA DML. We determined surface mass balance (SMB) averaged over various time scales late Holocene based on studies snow pits firn cores, addition to radar data. find that large-scale distribution SMB depends elevation...

10.5194/tc-5-1057-2011 article EN cc-by ˜The œcryosphere 2011-11-28

The evolution of the structure a 112.59 m long firn core recovered at Dome Fuji, East Antarctica, was investigated in order to improve understanding densification and bubble formation processes, which are important for interpreting local insolation proxies used astronomical dating deep ice cores. Using selected samples, we measured physical properties including (1) relative dielectric permittivities both vertical horizontal planes, (2) bulk density resolution millimeters, (3)...

10.1029/2008jf001143 article EN Journal of Geophysical Research Atmospheres 2009-09-01

Abstract The surface mass balance (SMB) at Dome Fuji, East Antarctica, was estimated using 36 bamboo stakes (grid of 6 × 6, placed 20 m intervals) from 1995 to 2006. heights the stake tops snow were measured 0.5 cm resolution twice monthly in 1995, 1996, 1997 and 2003, once a year for rest study period. To account settling, average density base during measurements used converting stake-height data SMB. annual SMB 2006 Fuji 27.3 ± 1.5 kg −2 −1 . This result agrees well with AD 1260 1993 (26.4...

10.3189/002214308784409062 article EN Journal of Glaciology 2008-01-01

Abstract. The Toba eruption that occurred some 74 ka ago in Sumatra, Indonesia, is among the largest volcanic events on Earth over last 2 million years. Tephra from this has been spread vast areas Asia, where it constitutes a major time marker close to Marine Isotope Stage 4/5 boundary. As yet, no tephra associated with identified Greenland or Antarctic ice cores. Based new accurate dating of and accurately dated European stalagmites, event known occur between onsets interstadials (GI) 19...

10.5194/cp-9-749-2013 article EN cc-by Climate of the past 2013-03-19

The δD temperature proxy in Antarctic ice cores varies parallel with CO2 through glacial cycles. However, these variables display a puzzling asynchrony. Well-dated records of Southern Ocean will provide crucial information because the is likely key regulating variations. Here, we perform multiple isotopic analyses on an core and estimate variations at this site oceanic moisture source over past 720,000 years, which extend longest by 300,000 years. affected large local insolation that are...

10.1038/s41467-018-03328-3 article EN cc-by Nature Communications 2018-02-28

Abstract. The isotopic compositions of oxygen and hydrogen in ice cores are invaluable tools for the reconstruction past climate variations. Used alone, they give insights into variations local temperature, whereas taken together can provide information on climatic conditions at point origin moisture. However, recent analyses snow from shallow pits indicate that signal become erased very low accumulation regions, due to processes reworking. signal-to-noise ratio decreases then only be...

10.5194/tc-10-837-2016 article EN cc-by ˜The œcryosphere 2016-04-15

ABSTRACT In order to better understand the densification of polar firn, firn cores from three sites within ~10 km Dome Fuji, Antarctica, were investigated using surrogates density: dielectric permittivities ε v and h at microwave frequencies with electrical fields in vertical horizontal planes respectively. Dielectric anisotropy Δ (= − ) was then examined as a surrogate anisotropic geometry firn. We find that layered is explained result complex effects two phenomena commonly occur sites....

10.1017/jog.2016.16 article EN cc-by-nc-nd Journal of Glaciology 2016-02-01
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