A5021119255- Corneal surgery and disorders
- Brucella: diagnosis, epidemiology, treatment
- Corneal Surgery and Treatments
- Glaucoma and retinal disorders
- Hepatocellular Carcinoma Treatment and Prognosis
- Ocular Surface and Contact Lens
- Galectins and Cancer Biology
- Burkholderia infections and melioidosis
- Mesenchymal stem cell research
- Salmonella and Campylobacter epidemiology
- Animal Diversity and Health Studies
- Ophthalmology and Visual Impairment Studies
- Atherosclerosis and Cardiovascular Diseases
- Cancer, Stress, Anesthesia, and Immune Response
- Retinal and Macular Surgery
- Nasal Surgery and Airway Studies
- Education and Learning Interventions
- Advanced Text Analysis Techniques
- Morphological variations and asymmetry
- Connective tissue disorders research
- Ocular Infections and Treatments
- Liver Disease and Transplantation
- Hepatitis C virus research
- Web Data Mining and Analysis
- Monoclonal and Polyclonal Antibodies Research
Northwest A&F University
2021-2025
Chang Gung University
2025
Guangdong University of Foreign Studies
2024
The First Affiliated Hospital, Sun Yat-sen University
2023
Zhongshan Hospital
2023
Fudan University
2023
Sun Yat-sen University
2023
University of Liverpool
2019-2023
Ministry of Agriculture, Livestock, and Food Supply
2021-2022
Fujian Provincial Cancer Hospital
2016-2021
<title>Abstract</title> <italic>Brucella</italic> spp. are facultative intracellular bacteria that infect and induce brucellosis in a diverse range of mammalian hosts. The disease causes major global economic losses also is worldwide threat to public health security. Characterization bacterial host factors promote survival key for the prevention control brucellosis. In this study, we identified proteins involved <italic>Brucella abortus</italic> A19 RAW264.7 macrophage cells by liquid...
Abstract Background Rhinolaryngoscopes are one of the most widely used tools by otolaryngologists and speech-language pathologists in current clinical practice. However, there is limited data on adverse events associated with or caused use rhinolaryngoscopes. Objective In this study, we Manufacturer User Facility Device Experience (MAUDE) database aim providing insights that may assist better understanding limitations these devices selecting appropriate procedures for their specific setting....
This paper aims to present a novel full-eye biomechanical material model that incorporates the characteristics of ocular tissues at microstructural level, and use analyse age-related stiffening in tissue behaviour. The collagen content tissues, as obtained using X-ray scattering measurements, was represented by sets Zernike polynomials covered both cornea sclera, then used reconstruct maps fibril magnitude orientation on three-dimensional geometry eye globe. Fine-mesh finite-element (FE)...
To evaluate the impact of soft contact lens eye-fit on optical power by computational modelling and to produce correction maps for reversing this during design process.Finite element models spherical toric hydrogel lenses at varying nominal powers -20 D +20 D, base curves radii (R1b) 8.2, 8.5, 8.8 mm, overall diameters (d3) 14.5, 15.0, 15.5 mm were generated. Lenses fitted eye generated with human eyes' topography data. Combined eye-lens simulations run under boundary conditions tears'...
The aim of the study was to investigate possibility human umbilical cord mesenchymal stem cells (UC-MSCs) surviving and differentiating into hepatocyte-like in partially hepatectomized model rats. MSCs were isolated from cultured with collagenase digestion. Cell surface markers detected fifth generation UC-MSCs labeled PKH26. rats injected transplanted through portal vein. survival cells, differentiation conditions expression hepatic marker albumin observed at post-transplantation 1, 2 3...
This study aimed to analyse microstructure data on the density and orientation of collagen fibrils in whole eye globes propose an effective method for preparation use numerical simulations eye's biomechanical performance. Wide-angle X-ray scattering was applied seven healthy ex-vivo human eyes. Each dissected into anterior a posterior cup, radial incisions were used flatten tissue before characterisation. A developed obtained build realistic 3D maps fibril covering globe. At central cornea,...
To investigate the safety and efficacy of transcatheter arterial chemoembolization (TACE) with embospheres for treatment unresectable hepatocellular carcinoma (HCC).Patients HCC who were treated TACE followed by embosphere (Embo-TACE) or conventional (cTACE) between May 2010 March 2014 retrospectively included in this study. The Embo-TACE group received lipiodol chemotherapeutic agent emulsion, embospheres. cTACE gelatin sponge pellets. Time to progression (TTP), overall survival (OS),...
This study aims to estimate the reduction in collagen fibril density within central 6 mm radius of keratoconic corneas through processing microstructure and videokeratography data. Collagen distribution maps topography were obtained for seven six healthy corneas, topographic features assessed detect calculate area cone each eye. The was estimated with reference same region characteristic corneas. Together minimum thickness mean corneal refractive power, correlated fibrils. For considered,...
UVA/riboflavin corneal cross-linking (CXL) is a common used approach to treat progressive keratoconus. This study aims investigate the alteration of stiffness following CXL by mimicking inflation eye under in vivo loading conditions. Seven paired porcine globes were involved test examine behaviour. Cornea-only model was constructed using finite element method, without considering deformation contribution from sclera and limbus. Inverse analysis conducted calibrate non-linear material...
This study aims to estimate the material properties of porcine vitreous while testing it in close its natural physiological conditions. Eighteen eyes were tested within 48 h post-mortem. A custom-built computer-controlled test rig was designed support, load and monitor behaviour eye globes being subjected dynamic rotation cycles mimicking saccade movement. Specimens glued base a container, surrounded by gelatin, frozen cut half expose vitreous. After thawing, container concentric rotations...
We previously reported that in double deficient nude.xid mice B cells failed to develop and their bone marrow did not produce mature vitro. However, when progenitors from were placed on a preestablished normal stromal cell line (AC6) they differentiated into surface IgM+ cells. This raised the possibility of deficiency nude such incapable supporting maturation X-linked immune (xid) Here we ask whether have ability support xid lymphopoiesis. A primary layer derived supported differentiation...
Abstract Background Brucella 19 strain vaccines are widely used to prevent brucellosis in cattle. The vaccine antibodies generally acknowledged persist for less than 12 months after immunization. real rate of persistent may be a difference because different feeding management and immunization schedules. effect the correlation between persistence induced by field infection remains unclear northwest China. Results We revealed that A19 dairy herds more months. established PCR method identifying...
Abstract News recommendation is a form of smart technology designed to offer users news content that matches their interests according preferences and interests. Nevertheless, current methodologies exhibit significant limitations. Traditional models often rely on simple random negative sampling for training, an approach insufficiently captures the patterns users' clicking behavior, thereby undermining model's effectiveness. Furthermore, these systems face challenges in insufficient modeling...
(1) Background: One method of eradicating brucellosis is to cull cattle that test positive for antibodies 12 months after being vaccinated with the 19-strain vaccine. Variations in immunization regimens and feeding practices may contribute differences rate persistent antibodies. We conducted this study investigate real Brucella antibody field strains
Calf diarrhea is a prevalent and significant health issue in dairy farming, severely impacting feed intake, weight gain, survival rates young calves. This study aimed to investigate the microbial composition antibiotic resistance profiles of diarrheic calves provide insights into epidemiology management condition. The prevalence 1685 was analyzed. Rectal fecal samples were collected from five healthy Holstein on large farm Shaanxi Province, China. High-throughput 16S-rRNA sequencing PCR...
The study presents an averaged anterior eye geometry model combined with a localised material that is straightforward, appropriate and amenable for implementation in finite element (FE) modelling.
Occurrence of portal vein tumor thrombus (PVTT) worsens the outcomes hepatocellular carcinoma (HCC) and imparts high economic burden on society. Patients with risks having hypercoagulation are more likely to experience thrombosis. Herein, we examined how preoperative international normalized ratio (INR) was related incidence extent PVTT, associated survival in HCC patients following R0 liver resection (LR).Patients PVTT were enrolled from six major hospitals China. The overall (OS)...
To simulate numerically the collagen fibril reorientation observed experimentally in cornea.Fibril distribution corneal strip specimens was monitored using X-ray scattering while under gradually increasing axial loading. The data were analysed at each strain level order to quantify changes angular of fibrils with growth. resulting relationship between stain and adopted a constitutive model control mechanical anisotropy tissue material. outcome validated against experimental measurements...