A5010541472- Meningioma and schwannoma management
- Glioma Diagnosis and Treatment
- Intracranial Aneurysms: Treatment and Complications
- Neurofibromatosis and Schwannoma Cases
- Traumatic Brain Injury and Neurovascular Disturbances
- Trigeminal Neuralgia and Treatments
- Spinal Fractures and Fixation Techniques
- Fetal and Pediatric Neurological Disorders
- Cerebrospinal fluid and hydrocephalus
- Neurosurgical Procedures and Complications
- Neonatal and fetal brain pathology
- MicroRNA in disease regulation
- Brain Metastases and Treatment
- Facial Nerve Paralysis Treatment and Research
- Intracerebral and Subarachnoid Hemorrhage Research
- Vascular Malformations Diagnosis and Treatment
- Cancer-related molecular mechanisms research
- Circular RNAs in diseases
- Spinal Dysraphism and Malformations
- Moyamoya disease diagnosis and treatment
- Caveolin-1 and cellular processes
- Adenosine and Purinergic Signaling
- Acute Ischemic Stroke Management
- Head and Neck Surgical Oncology
- Spine and Intervertebral Disc Pathology
Bursa Uludağ Üni̇versi̇tesi̇
2012-2025
Loma Linda University
2018-2020
Neurological Surgery
2017-2019
University of Wisconsin–Madison
2017-2019
Düzce Üniversitesi
2019
Medical Education Institute
2017-2018
Accreditation Council for Graduate Medical Education
2017-2018
Highland Community College - Illinois
2017
Sivas State Hospital
2016
SurveyMonkey (United States)
2016
The effects of Olea europaea leaf extract (OLE) phenolics, including oleuropein (OL), hydroxytyrosol (HT), tyrosol (TYR), and rutin against glioblastoma (GB), independently in combination with temozolomide (TMZ), were investigated T98G A172 cells. Cell growth was assessed by WST-1, real-time cell analysis, colony formation, cycle distribution assays. A dual acridine orange propidium iodide (AO/PI) staining annexin V assay determined viability. sphere-forming assay, an intracellular oxidative...
OBJECTIVE Cystic vestibular schwannomas (CVSs) are a subgroup of (VSs) that reported to be associated with unpredictable clinical behavior and unfavorable postoperative outcomes. The authors aimed review their experience microsurgical treatment CVSs in terms extent resection facial nerve (FN) function compare these outcomes those solid counterparts. METHODS Two hundred-eleven VS patients were treated surgically between 2006 2017. Tumors defined as cystic when preoperative neuroimaging...
Abstract Background Cardiac arrest survivors suffer from neurological dysfunction including cognitive impairment. Cerebral mast cells, the key regulators of neuroinflammation contribute to neuroinflammation-associated dysfunction. Mast cell tryptase was demonstrated have a proinflammatory effect on microglia via activation microglial protease-activated receptor-2 (PAR-2). This study investigated potential anti-neuroinflammatory inhibition and underlying mechanism PAR-2/p-p38/NFκB signaling...
Glioblastoma represents extreme anaplasia in astrocytic tumors.In spite of this aggressiveness, extracranial metastasis glioblastoma is very rare and has been documented only a few patients the literature.In article, 30-year-old woman with secondary associated distant was presented.In September 2008, an intracranial lesion left frontal region diagnosed by magnetic resonance imaging (MRI) after admission to hospital headache seizure subsequently resected.The histology revealed anaplastic...
Global cerebral ischemia-induced neuroinflammation causes neurofunctional impairment following cardiac arrest. Previous studies have demonstrated that the activation of protease-activated receptor-2 (PAR-2) contributes to neuroinflammation. In present study, we aimed determine potential treatment effect PAR-2 inhibition against in setting asphyxial CA (ACA) rats.A total 116 adult, male Sprague-Dawley rats were randomly divided into Sham (n = 18) and ACA 98) groups. Time course, short-term...
to 55 95% in later stages (20).The procedure is generally useful for unilateral nociceptive pain.The percutaneous technique was introduced by Mullan 1963 (17).In 1965, Rosomoff et al. used radiofrequency (RF) current produce a lesion (23).Kanpolat described the usage of 9).However, broad use intraspinal narcotics has affected spinal cord ablation procedures, but CT-guided cervical cordotomy (PCC) still most effective patients with intractable pain.AIm: To evaluate safety and effectiveness...
Objective: This study was designed to conduct molecular classification based on IDH1/2, TERT, ATRX, and DAXX changes in pediatric adult primary glioblastoma (GB) analyze the potential interaction of LncRNA MALAT1 determined homogeneous subgroups.Methods: We analyzed expression profiles ATRX/DAXX using qRT-PCR method IDH TERT mutation status DNA sequencing analysis 85 GB patients.Results:IDH1 observed 5 (5.88%) 65 (76.47%) patients. ATRX were detected 18 (21.18%) 7 (8.24%) loss associated...
ObjectiveThe appropriate treatments for the different molecular subgroups of medulloblastomas are challenging to determine. Hence, this study aimed examine expression profiles long non-coding RNAs (LncRNAs) determine a marker that may be important treatment selection in these subgroups.MethodsChanges LncRNAs tissues patients with medulloblastoma, which classified into four according their clinical characteristics and gene profiles, were examined via reverse transcription polymerase chain...
Dural arteriovenous fistulas (DAVFs) of the sphenoparietal sinus are extremely rare. In present report, we describe a 46-year-old male patient who presented with headache, pulsatile tinnitus on right side, and single course focal seizure starting 2 months after closed head injury causing temporal occipital bone fractures. Cranial magnetic resonance imaging which was obtained 11 showed white matter necrosis in frontal lobe while digital subtraction angiography (DSA) revealed right-sided DAVF...
Surgical access to the petroclival region poses a challenge neurosurgeons. A wide range of approaches has been demonstrated in past. In this video, authors present 69-year-old male patient who presented with 3-month history worsening left-sided numbness. The tumor was totally removed 2 sessions via anterior transpetrosal and retrosigmoid approaches, respectively. demonstrate separate skull base resect meningioma discuss pitfalls problems management for challenging meningiomas. suggest that...