A5057688373- Dementia and Cognitive Impairment Research
- Health Systems, Economic Evaluations, Quality of Life
- Alzheimer's disease research and treatments
- Migration, Health and Trauma
- Intensive Care Unit Cognitive Disorders
- Chronic Disease Management Strategies
- Frailty in Older Adults
- Sleep and related disorders
- Schizophrenia research and treatment
- Circadian rhythm and melatonin
- Interpreting and Communication in Healthcare
- Diet and metabolism studies
- Migration and Labor Dynamics
- Vagus Nerve Stimulation Research
- Nutrition and Health in Aging
- Olfactory and Sensory Function Studies
- Pharmaceutical Practices and Patient Outcomes
- Aging and Gerontology Research
- Palliative Care and End-of-Life Issues
- Vaccine Coverage and Hesitancy
- Global Health Workforce Issues
- Long-Term Effects of COVID-19
- Advanced Chemical Sensor Technologies
- Consumer Attitudes and Food Labeling
- Pain Management and Placebo Effect
Stockholm University
2023-2025
Karolinska Institutet
2023-2025
Sapienza University of Rome
2016-2023
Several chronic diseases accelerate cognitive decline; however, it is still unknown how different patterns of multimorbidity influence individuals' trajectories across the continuum.We aimed to investigate impact and specific on transitions stages (normal cognition, impairment, no dementia [CIND], dementia) death.We included 3122 dementia-free individuals from Swedish National study Aging Care in Kungsholmen. Using fuzzy c-means cluster analysis, multimorbid participants were classified into...
Background and purpose The phenomenon of dementia amongst migrants ethnic minorities represents an emerging concern for European healthcare systems, posing additional challenges in terms clinical approach, access to care resource utilization. aim the present study was estimate cases immigrant older subjects living Europe each country. Methods estimated (i.e. 65+) Union ( EU ‐28) Free Trade Association member states were calculated by multiplying number (obtained through data provided...
Abstract INTRODUCTION We quantified the association of mild (ie, involving one or two body systems) and complex ≥3 multimorbidity with structural brain changes in older adults. METHODS included 390 dementia‐free participants aged 60+ from Swedish National Study on Aging Care Kungsholmen who underwent magnetic resonance imaging at baseline after 3 and/or 6 years. Using linear mixed models, we estimated between total tissue, ventricular, hippocampal, white matter hyperintensities volumes....
We explored the variations of blood biomarkers Alzheimer's disease (AD) by chronic diseases and systemic inflammation.
Abstract Introduction Approximately 2 million people in Italy are currently living with dementia or mild cognitive impairment (MCI), and 4 involved as family members caregivers. Considering the significant impact of dementia, Italian Ministry Health entrusted National Institute (Istituto Superiore di Sanità) development a guideline within Guideline System (Sistema Nazionale Linee Guida, SNLG) on diagnosis treatment MCI. The main objective was to provide evidence-based recommendations aimed...
INTRODUCTION: Chronic pain is a debilitating condition that impacts over 17 million people around the world. While spinal cord stimulation (SCS) promising therapy, patient selection remains challenging due to an inability predict who will experience relief. METHODS: Patients were scheduled for permanent SCS implant surgery their chronic back and/or leg recruited study. Pain outcome data (e.g., Numeric Rating Scale, Catastrophizing Scale) collected preoperatively and 3 months after surgery....
Diet can impact cognitive aging, but comprehensive data from human studies is lacking and the underlying biological mechanisms are still not fully understood. To investigate associations between two dietary patterns consistently linked to inflammation brain health [the Mediterranean diet (MDS) inflammatory potential of (EDII)] five blood-based biomarkers Alzheimer´s disease (AD) in a sample dementia-free community-dwelling older adults. We used cross-sectional Swedish National Study on Aging...
Abstract Evidence regarding the clinical validity of blood biomarkers Alzheimer’s disease (AD) in general population is limited. We estimated hazard and predictive performance six AD for incident all-cause dementia—the ratio amyloid-β 42 to 40 levels tau phosphorylated at T217 (p-tau217), T181 (p-tau181), total tau, neurofilament light chain (NfL), glial fibrillary acidic protein (GFAP)—in a cohort 2,148 dementia-free older adults from Sweden, who were followed up 16 years. In multi-adjusted...
The term sundowning is used to describe the emergence or worsening of neuropsychiatric symptoms in late afternoon early evening people with dementia.Our aim was evaluate sundowning's prevalence and clinical manifestations among patients attending a tertiary memory clinic investigate its neuropsychological correlates.Patients dementia our were enrolled study. Sundowning identified through specifically designed questionnaire. Sociodemographic features sundowners non-sundowners compared,...
More than 500,000 dementia cases can be estimated among migrants living in Europe. There is the need to collect "real world" data on preparedness of healthcare services support inclusion public health response dementia. The present study aimed (i) estimate number referred Italian memory clinics (Centers for Cognitive Disorders and Dementia [CCDDs]) (ii) identify possible barriers resources provision diversity-sensitive care.A survey all CCDDs was conducted between December 2020 April 2021....
We aimed to explore the awareness and preparedness of dementia caregivers people with mild cognitive deficits on how prevent COVID-19 infection cope indirect consequences pandemic. A total 139 patient-caregiver dyads received a telephone survey 109 completed survey. The majority respondents reported having moderate-to-good knowledge typical manifestations COVID-19. Conversely, only few them were informed atypical presentations recognize emergency warning signs. Filling gaps in most...