Xiaofeng Lu

ORCID: 0000-0003-0160-0078
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About
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Research Areas
  • X-ray Diffraction in Crystallography
  • Crystallization and Solubility Studies
  • Metal-Organic Frameworks: Synthesis and Applications
  • Analytical Chemistry and Chromatography
  • Analytical chemistry methods development
  • Magnetism in coordination complexes
  • Covalent Organic Framework Applications
  • Molecular Sensors and Ion Detection
  • Organic and Molecular Conductors Research
  • Microfluidic and Capillary Electrophoresis Applications
  • Electrochemical sensors and biosensors
  • Bone Metabolism and Diseases
  • Analytical Chemistry and Sensors
  • Circadian rhythm and melatonin
  • Crystallography and molecular interactions
  • Adsorption and biosorption for pollutant removal
  • Oral microbiology and periodontitis research
  • Mesoporous Materials and Catalysis
  • Extraction and Separation Processes
  • Perovskite Materials and Applications
  • Cholinesterase and Neurodegenerative Diseases
  • Chemical Synthesis and Characterization
  • Catalytic Processes in Materials Science
  • Nanopore and Nanochannel Transport Studies
  • Sulfur Compounds in Biology

Union Hospital
2020-2025

Huazhong University of Science and Technology
2020-2025

Wuhan University
2020-2025

Hubei Zhongshan Hospital
2020-2025

State Key Laboratory of Pollution Control and Resource Reuse
2025

Nanjing University
2025

Lanzhou Institute of Chemical Physics
2017-2024

Guangxi University
2024

Chinese Academy of Sciences
2012-2024

Union Hospital
2021-2024

Abstract Background Inflammatory responses in the CNS mediated by activated glial cells play an important role host-defense but are also involved development of neurodegenerative diseases. Resveratrol is a natural polyphenolic compound that has cardioprotective, anticancer and anti-inflammatory properties. We investigated capacity resveratrol to protect microglia astrocyte from inflammatory insults explored mechanisms underlying different inhibitory effects on astrocytes. Methods A murine...

10.1186/1742-2094-7-46 article EN cc-by Journal of Neuroinflammation 2010-08-17

Bone‑related diseases comprise a large group of common diseases, including fractures, osteoporosis and osteoarthritis (OA), which affect number individuals, particularly the elderly. The progressive destruction loss alveolar bone caused by periodontitis is specific type loss, has high incidence markedly reduces quality life patients. With existing methods prevention treatment, mortality bone‑related are still gradually increasing, creating significant financial burden to societies worldwide....

10.3892/ijmm.2021.4915 article EN cc-by-nc-nd International Journal of Molecular Medicine 2021-03-17

Acetylcholinesterase (AChE) plays crucial roles in numerous physiological processes such as cell differentiation, apoptosis, and nerve tissue developments. Hence, it is highly necessary to design a fluorescent probe for monitoring AChE activity complex living organisms. In this work, near-infrared (NIR) off-on (CyN) was developed detection. CyN exactly synthesized by introducing an N,N-dimethyl carbamyl moiety hemicyanine (CyOH). can "light up" strong NIR fluorescence through cleavage...

10.1021/acssensors.9b01717 article EN ACS Sensors 2019-12-25

Abstract The utilization of optimal orthodontic force is crucial to prevent undesirable side effects and ensure efficient tooth movement during treatment. However, the sensitivity existing detection techniques not sufficient, criteria for evaluating have been yet established. Here, by employing 3D finite element analysis methodology, we found that apical distal region (A-D region) mesial roots particularly sensitive in rats. Tartrate-resistant acidic phosphatase (TRAP)-positive osteoclasts...

10.1038/s41368-024-00284-1 article EN cc-by International Journal of Oral Science 2024-02-28

A metal organic framework (MOF-235) was fabricated by a simple solvothermal method and utilized as an adsorbent for the selective removal of electron-rich conjugated dyes.

10.1039/c9nj03370j article EN New Journal of Chemistry 2019-01-01

Herein, a novel, fusiform-like magnetic metal–organic framework material (Fe<sub>3</sub>O<sub>4</sub>-NH<sub>2</sub>@MOF-235) was fabricated by facile two-step solvothermal approach.

10.1039/c9nj01988j article EN New Journal of Chemistry 2019-01-01

We reporte the double-layer hydrogel-coated mesoporous silica material as a new stationary phase for liquid chromatography. The method of combining physical coating and chemical was to apply hydrogel on surface silica, finally, type chromatography with in situ functional obtained. This hydrogel-functionalized also exhibits certain temperature responsiveness. Experimental results show that this response is mainly due changes hydrogen bonding between analyte at different temperatures column...

10.1021/acs.analchem.1c03514 article EN Analytical Chemistry 2021-11-24

Abstract Bone regeneration remains a great clinical challenge. Low intensity near-infrared (NIR) light showed strong potential to promote tissue regeneration, offering promising strategy for bone defect regeneration. However, the effect and underlying mechanism of NIR on remain unclear. We demonstrated that in rat skull model was significantly accelerated with low-intensity stimulation. In vitro studies stimulation could osteoblast differentiation mesenchymal stem cells (BMSCs) MC3T3-E1...

10.1038/s41368-022-00207-y article EN cc-by International Journal of Oral Science 2022-11-14

Introduction Allergic rhinitis (AR) remains a kind of nasal hypersensitivity illness with considerable surge in incidence across the globe. Plasminogen activator inhibitor type 2 (SERPINB2) is an inflammatory mediator that can be also activated by aryl hydrocarbon receptor (AhR), nuclear modulates response to environmental stimuli. This work was devoted investigation into role SERPINB2 AR and its relationship AhR. Methods In human epithelial cells (HNEpCs) stimulated interleukin-4 (IL-4) or...

10.1159/000543410 article EN International Archives of Allergy and Immunology 2025-02-08
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