A5100775507- Air Quality and Health Impacts
- Cleft Lip and Palate Research
- Climate Change and Health Impacts
- Fluid Dynamics and Turbulent Flows
- Corporate Finance and Governance
- Ovarian function and disorders
- Nutritional Studies and Diet
- Cardiovascular Health and Risk Factors
- Urban Heat Island Mitigation
- Building Energy and Comfort Optimization
- Reproductive Biology and Fertility
- Global Health Care Issues
- Sleep and related disorders
- Liver Disease Diagnosis and Treatment
- COVID-19 epidemiological studies
- Pregnancy and preeclampsia studies
- Folate and B Vitamins Research
- Energy and Environment Impacts
- Genetic Associations and Epidemiology
- Noise Effects and Management
- Assisted Reproductive Technology and Twin Pregnancy
- Health, Environment, Cognitive Aging
- Cardiovascular Health and Disease Prevention
- Obesity, Physical Activity, Diet
- Nutrition, Genetics, and Disease
Peking University
2017-2025
Wuhan Polytechnic University
2025
Shanghai University of Engineering Science
2025
Zhejiang University
2024-2025
Peking University Third Hospital
2022-2024
Education University of Hong Kong
2024
Lingnan Normal University
2022-2024
China Aerospace Science and Industry Corporation (China)
2024
China Three Gorges University
2022-2024
Research Institute of Petroleum Exploration and Development
2019-2024
Little is known about the relation between long-term joint exposure to various ambient air pollutants and incidence of heart failure (HF). We aimed assess association with HF risk examine modification effect genetic susceptibility.
Elevated plasma homocysteine (Hcy) levels have been indicated as a strong and modifiable risk factor of ischemic stroke; the previous studies shown that exposure to Hcy activates cultured microglia. However, whether neurotoxicity involves microglia activation following brain ischemia underlying mechanisms remains incompletely understood.The cerebral damage was evaluated by staining with 2,3,5-triphenyltetrazolium chloride, hematoxylin-eosin, Fluoro Jade B. The state assessed via...
Background Air pollution has been related to incidence of type 2 diabetes (T2D). We assessed the joint association various air pollutants with risk T2D and examined potential modification by obesity status genetic susceptibility on relationship. Methods findings A total 449,006 participants from UK Biobank free at baseline were included. Of all study population, 90.9% white 45.7% male. The had a mean age 56.6 (SD 8.1) years old body mass index (BMI) 27.4 4.8) kg/m . Ambient pollutants,...
Abstract Background Recent studies suggest potential interactions of air pollutants with dietary factors and genetic susceptibility on mortality risk; however, evidence from prospective is still lacking. We aimed to assess the association between pollution mortality, investigate modification effects a healthy diet susceptibility. Methods A total 386 937 participants were enrolled 2006 2010 followed up 2018 in UK Biobank study. The annual average pollutant concentrations particulate matter...
OBJECTIVE Circulating vitamin D concentrations have been associated with the risk of type 2 diabetes (T2D), but results are inconsistent. Emerging evidence suggests that metabolism is linked to sleep behaviors. We investigated prospective association between serum 25-hydroxyvitamin (25OHD) and incident T2D whether such was modified by RESEARCH DESIGN AND METHODS The study included 350,211 individuals free in UK Biobank. Serum 25OHD (nmol/L) were measured. Five behaviors including duration,...
Abstract The elevated level of the amino acid metabolite homocysteine (Hcy) is known as a risk factor for ischemic stroke. molecular mechanisms responsible neurotoxicity Hcy remain largely unknown in brains. previous studies have shown that decreases proliferation and viability neural stem cells (NSCs) vivo vitro. Autophagy required maintenance NSCs homeostasis. In current study, we hypothesized toxic effect on may involve changes autophagy following cerebral ischemia/reperfusion injury....
Background The effects of ambient particulate matter (PM) pollution on pneumonia in adults are inconclusive, and few scientific data a national scale have been generated low- or middle-income countries, despite their much higher PM concentrations. We aimed to examine the association between levels hospital admissions for Chinese adults. Methods findings A nationwide time series study was conducted China 2014 2017. Information daily 2014–2017 collected from database Urban Employee Basic...
Abstract Background Individual unhealthy sleep behaviours have been associated with increased risks of all‐cause mortality and deaths due to cardiovascular disease (CVD) or cancer. The evidence regarding the association patterns these is limited. Objective To examine associations all‐cause, CVD cancer in a large prospective cohort. Methods This cohort study included 283,443 adults from UK Biobank without at baseline. We created healthy score combining five individual behaviours. Results...
Abstract Purpose Predictively diagnosing infectious diseases helps in providing better treatment and enhances the prevention control of such diseases. This study uses actual data from a hospital. A multiple disease diagnostic model (MIDDM) is designed for conducting multi-classification so as to assist clinical infectious-disease decision-making. Methods Based on hospital medical records December 2012 2020, deep learning research constructed. The includes 20,620 cases covering seven types...
Few large multicity studies have assessed acute effect of tropospheric ozone pollution on pneumonia risk. We aimed to examine the relation between day-to-day changes in concentrations and hospital admissions for China. conducted a national time-series study 184 major Chinese cities from 2014 2017. City-specific was evaluated using an over-dispersed generalized additive model. Random-effects meta-analysis pool city-specific estimates. Two-pollutant models were fitted test robustness...
Background: Knee osteoarthritis (KOA) provides many challenges on the healthcare system. However, few studies have reported epidemiology, particularly in a large population. Our study aimed to estimate prevalence, incidence, trends, and patterns of diagnosed KOA China. Methods: This was longitudinal study. We used health insurance claims 17.7 million adults from 2008–2017 identify people with KOA. Trends prevalence incidence were analyzed using joinpoint regression. Results: identified...
The association of tea or coffee consumption with gout is inconsistently reported. Few prospective studies have explored their dose-response relationship. Therefore, we aimed to quantitatively investigate the between tea, and risk developing gout.The study included 447 658 participants in UK Biobank who were initially free gout. Tea assessed at baseline. We used Cox proportional hazards models estimate associations tea/coffee incident gout, restricted cubic spline added evaluate...
Abstract The proficiency of phyllosphere microbiomes in efficiently utilizing plant-provided nutrients is pivotal for their successful colonization plants. methylotrophic capabilities Methylobacterium/Methylorubrum play a crucial role this process. However, the precise mechanisms facilitating efficient remain elusive. In present study, we investigate significance methanol assimilation shaping success mutualistic relationships between methylotrophs and A set strains originating from...
To explore the multimorbidity prevalence and patterns among middle-aged older adults from China. Data on thirteen chronic diseases were collected 2,097,150 participants aged over 45 years between January 1st 2011 December 31st 2015 Beijing Medical Claim for Employees. Association rule mining hierarchical cluster analysis applied to assess patterns. Multimorbidity was 51.6% 81.3% in groups, respectively. The most prevalent disease pair that of osteoarthritis rheumatoid arthritis (OARA) with...