A5041638115- Gestational Diabetes Research and Management
- Obesity, Physical Activity, Diet
- Birth, Development, and Health
- Gastric Cancer Management and Outcomes
- Genetic Associations and Epidemiology
- Cardiovascular Health and Risk Factors
- Adipose Tissue and Metabolism
- Pregnancy and preeclampsia studies
- Breastfeeding Practices and Influences
- Poverty, Education, and Child Welfare
- Child Nutrition and Water Access
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Regulation of Appetite and Obesity
- Early Childhood Education and Development
- Lipid metabolism and biosynthesis
- Nutritional Studies and Diet
- Hormonal and reproductive studies
- Metastasis and carcinoma case studies
- Gastrointestinal Tumor Research and Treatment
- Infant Nutrition and Health
- Nitric Oxide and Endothelin Effects
- Child Abuse and Trauma
- Sodium Intake and Health
- Hepatitis Viruses Studies and Epidemiology
- Metabolomics and Mass Spectrometry Studies
Shenzhen Maternity and Child Healthcare Hospital
2024-2025
Shenzhen Institutes of Advanced Technology
2023-2025
Chinese Academy of Sciences
2023-2025
Shenzhen University Health Science Center
2025
Jinan University
2021-2023
Peking University
2006-2022
Chinese PLA General Hospital
2022
Tulane University
2020-2022
Chinese People's Liberation Army
2022
Maternal and Child Health Care Hospital of Bao'an
2022
Abstract Background Recent studies suggest potential interactions of air pollutants with dietary factors and genetic susceptibility on mortality risk; however, evidence from prospective is still lacking. We aimed to assess the association between pollution mortality, investigate modification effects a healthy diet susceptibility. Methods A total 386 937 participants were enrolled 2006 2010 followed up 2018 in UK Biobank study. The annual average pollutant concentrations particulate matter...
BACKGROUND Gastric cancer (GC) is a heavy burden in China. Nutritional support for GC patients closely related to postoperative rehabilitation. However, the role of early oral feeding after laparoscopic radical total gastrectomy unclear and high-quality research evidence scarce. AIM To prospectively explore safety, feasibility short-term clinical outcomes patients. METHODS This study was prospective cohort conducted between January 2018 December 2019 based high-volume tertiary hospital A 206...
No consensus has yet been reached concerning whether there were significant differences in the vaginal microbiota according to maternal gestational diabetes mellitus (GDM) status. This study aimed compare of women with GDM and normal blood glucose before after delivery prospectively evaluate influence on dynamic changes from antepartum postpartum. included 20 patients 31 average pregnant who gave birth at Shenzhen Baoan Women's Children's Hospital. Vaginal secretions samples collected one...
The human lipidomic profile reflects lipid metabolism, including the early phase of pathophysiological changes associated with diseases. An investigation association between plasma and adolescent obesity might provide new insights into biological mechanisms obesity. Therefore, we aimed to investigate lipidome in Chinese adolescents using lipidomics.Using a combination liquid chromatography electrospray ionization tandem mass spectrometry, quantified 328 species from 24 classes subclasses 100...
Abstract Aims The present study aimed to prospectively evaluate the influence of gestational diabetes mellitus (GDM) on gut microbiota in 1- and 6-month-old offspring, as well dynamic changes from 1 6 months age. Methods Seventy-three mother-infant dyads (34 GDM vs 39 non-GDM) were included this longitudinal study. Two fecal samples collected for each infant at home by parents month age (“M1 phase”) again (“M6 phase”). Gut profiled 16S rRNA gene sequencing. Results Although no significant...
Hyphae, 2 to 8 days postinoculation (dpi), and haustoria, 5 dpi, were isolated from Uromyces appendiculatus infected bean leaves (Phaseolus vulgaris cv. Pinto 111) a separate cDNA library prepared for each fungal preparation. Approximately 10,000 hyphae 2,700 haustoria clones sequenced both the 5' 3' ends. Assembly of all sequences yielded 3,359 contigs 927 singletons. The U. compared with sequence data other rust fungi, Phakopsora pachyrhizi, fabae, Puccinia graminis. included large number...
Effects of MC4R variants in previous Chinese population studies were inconsistent. Gene-environment interactions might influence the effect on obesity, which was still unclear. We performed study to clarify association near gene with obesity-related phenotypes and gene-environment children adolescents. Two common (rs12970134 rs17782313) genotyped 2179 adolescents aged 7-18 years Beijing China. Associations between together analyzed. The A-alleles rs12970134 nominally associated risk...
The data about quality of care more than 70 countries were available from UNICEF but little was known China. We examined the status and explored its associations with developmental outcomes in Chinese children. A cross-sectional study probability proportional to size sampling method conducted 8 counties rural total 1927 children assessed on development using Ages Stages Questionnaires-Chinese (ASQ-C) based normative data. Nutritional derived anthropometric following WHO guidelines....
The meta-analyses of genome-wide association studies identified several waist-hip ratio (WHR) related loci in individuals European ancestry. Since the pattern fat distribution and relationship between glucose metabolism disturbance Chinese are different from those Europeans, present study aimed to explore individual cumulative effects WHR-related on glycemic phenotypes children.A total 2030 children were recruited two independent studies. Eleven single nucleotide polymorphisms (SNPs)...
Hepatocellular carcinoma (HCC) is one of the most common cancers in world. The landscape HCC's molecular alteration signature has been explored over last few decades. Even so, more comprehensive research still needed to improve understanding tumorigenesis and progression HCC, as well identify potential biomarkers for malignancy. In this research, a bioinformatics analysis was conducted based on publicly available databases from both Cancer Genome Atlas (TCGA) program gene expression omnibus...
Abstract Background Maternal gestational diabetes mellitus (GDM) had long-term influences on the health of their children. However, GDM oral microbiota, which was closely related to and systemic in offspring, were less documented. The present study aimed explore microbiota neonates born mothers with is differentially colonized compared those without GDM, whether any such differences persist 1 month age. Methods Oral samples collected from children ( n = 20) 34) at birth again an average age...
The associations among maternal depressive symptoms (MDS), mother-child interactions and early child development are poorly understood. This study aimed to explore the role of on between MDS development. A cross-sectional with a multistage sampling method was conducted in rural areas Central Western China. MDS, outcomes (communication, gross motor function, fine problem solving personal social skills) were assessed by Edinburgh Postpartum Depression Scale, Chinese version Ages Stages...
Operation is the primary therapeutic option for patients with distal gastrectomy. Braun anastomosis usually performed after Billroth II reconstruction, which wildly applied on gastrectomy because it believed to benefit patients. However, studies are needed confirm that.
<b><i>Objective: </i></b>This study aimed to examine associations of three single-nucleotide polymorphisms (SNPs) with obesity-related phenotypes in Chinese children. These SNPs were identified by a recent genome-wide association (GWA) among European Given that varied genetic backgrounds across different ethnicity may result association, it is necessary these ethnic population. <b><i>Methods: </i></b>A total 3,922 children, including 2,191...