A5027969166- Cardiovascular Function and Risk Factors
- Non-Invasive Vital Sign Monitoring
- Blood Pressure and Hypertension Studies
- Heart Failure Treatment and Management
- Heart Rate Variability and Autonomic Control
- Hemodynamic Monitoring and Therapy
- Liver Disease Diagnosis and Treatment
- Circadian rhythm and melatonin
- Cardiac pacing and defibrillation studies
- Acute Ischemic Stroke Management
- Infective Endocarditis Diagnosis and Management
- Atrial Fibrillation Management and Outcomes
- Cardiovascular and exercise physiology
- Adipose Tissue and Metabolism
- Antimicrobial Resistance in Staphylococcus
- Diet and metabolism studies
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Liver Diseases and Immunity
- Liver Disease and Transplantation
- Mitochondrial Function and Pathology
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Bacterial Identification and Susceptibility Testing
- Phagocytosis and Immune Regulation
- Parvovirus B19 Infection Studies
Hadassah Medical Center
2020-2025
Hebrew University of Jerusalem
2021-2025
University Medical Center
2024
Shaare Zedek Medical Center
2019
Diuretics are a mainstay therapy for congestive heart failure (CHF); however, over one-third of patients develop diuretic resistance. Second-generation artificial intelligence (AI) systems introduce variability into treatment regimens to overcome the compensatory mechanisms underlying loss effectiveness diuretics. This open-labeled, proof-of-concept clinical trial sought investigate ability improve resistance by implementing algorithm-controlled therapeutic regimens.Ten CHF with were...
Personal protective equipment (PPE) is crucial for infection prevention and effective only when worn correctly consistently. Health organizations often use education or inspections to mitigate non-compliance, but these are costly have limited success. This study developed a novel on-device, AI-based computer vision system monitor healthcare worker PPE adherence in real time. Using custom-built image dataset of 7142 images 11 participants wearing various combinations (mask, gloves, gown), we...
Intradialytic hypotension (IDH) is a severe complication of hemodialysis (HD) with significant impact on morbidity and mortality. In this study, we used wearable device for the continuous monitoring hemodynamic vitals to detect changes during HD attempted identify IDH. End-stage kidney disease patients were continuously monitored 15 min before starting session until after completion session, measuring heart rate (HR), noninvasive cuffless systolic diastolic blood pressure (SBP DBP), stroke...
Anticoagulants are a cornerstone of treatment in atrial fibrillation. Nowadays, direct oral anticoagulants (DOACs) extensively used for this condition developed countries. However, DOAC may be inappropriate certain patient populations, such as: patients with chronic kidney disease whom concentrations dangerously elevated; frail elderly an increased risk falls; significant drug–drug interactions (DDI) affecting either concentration or effect; at the extremes body mass “abnormal” volume...
Recent technological developments enable big data-driven insights on diurnal changes. This study aimed to describe the trajectory of multiple and advanced parameters using a medical-grade wearable remote patient monitor.Parameters were monitored for 24 h in 256 ambulatory participants who kept living their normal life. Parameters included heart rate, blood pressure, stroke volume, cardiac index, systemic vascular resistance, oxygen saturation, respiratory rate. Diurnal variations evaluated,...
Adropin is a peptide that was suggested to have role in cirrhosis. The present study aimed determine the ability use serum adropin levels improve their prediction accuracy as an adjunct current scores. In single-center, proof-of-concept study, were determined thirty-three cirrhotic patients. data analyzed correlation with Child-Pugh and MELD-Na scores, laboratory parameters, mortality. higher among patients died within 180 days (1,325.7 ng/dL vs. 870.3 ng/dL, p = 0.024) inversely correlated...
There are no clear guidelines for diuretic administration in heart failure (HF), and reliable markers needed to tailor treatment. Continuous monitoring of multiple advanced physiological parameters during diuresis may allow better differentiation patients into subgroups according their responses. In this study, 29 HF were monitored outpatient intravenous diuresis, using a noninvasive wearable multi-parameter monitor. Analysis changes these the course aimed recognize with different response...
Background The traditional classification of left ventricular hypertrophy (LVH), which relies on geometry, fails to correlate with outcomes among patients increased LV mass (LVM). Objectives To identify unique clinical phenotypes LVM using unsupervised cluster analysis, and explore their association outcomes. Methods Among the UK Biobank participants, was defined as index ≥72 g/m 2 for men, ≥55 women. Baseline demographic, clinical, laboratory data were collected from database. Using Ward's...
Abstract Background The traditional classification of left ventricular hypertrophy (LVH) solely based on geometry disregards associated comorbidities and clinical characteristics. We aimed to identify unique phenotypes LVH using unsupervised cluster analysis explore their association with outcomes. Methods From UK Biobank (UKBB) participants available mass (LVM) estimations, we identified those meeting CMR-based criteria for increased LVM: LVM index ≥ 72 g/m2 males 55 females. Baseline...
Retinal vascular occlusions are a significant cause of visual impairment in older adults, resulting ischemic retinal damage and sudden vision loss. This study evaluates the retinal, optic nerve head (ONH), choroidal capillary networks chronic acute-on-chronic hypoxia compared to normal controls using optical coherence tomography angiography (OCT-A).
Many trauma patients die from hemorrhagic shock in the military and civilian settings. Although two-thirds of victims reasons other than exsanguination, such as consequent cytokine storm, anti-inflammatory therapies failed to be utilized. Apoptotic cell-based treatments enhance innate ability exert systemic immunomodulation demonstrated several clinical applications hence might present a novel approach treatment.
Metabolic dysfunction-associated steatohepatitis is an advanced form of nonalcoholic fatty liver disease and a leading cause end-stage transplantation. Insulin resistance inflammation underlie the pathogenesis disease.