A5045392497- Lower Extremity Biomechanics and Pathologies
- Osteoarthritis Treatment and Mechanisms
- Total Knee Arthroplasty Outcomes
- Knee injuries and reconstruction techniques
- Immunodeficiency and Autoimmune Disorders
- Bone fractures and treatments
- Reproductive Health and Technologies
- Nuclear and radioactivity studies
- Bone Tissue Engineering Materials
- Sperm and Testicular Function
- Risk Perception and Management
- Connective tissue disorders research
- Hemophilia Treatment and Research
- Reproductive Biology and Fertility
- Orthopaedic implants and arthroplasty
- Risk and Safety Analysis
- Monoclonal and Polyclonal Antibodies Research
University of Leeds
2020-2024
University of Bristol
2021
Osteochondral grafts are used for repair of focal osteochondral lesions. Autologous the gold standard treatment; however, limited graft availability and donor site morbidity restrict use. Therefore, there is a clinical need different sources/materials which replicate natural cartilage function. Chitosan has been proposed this application. The aim study was to assess biomechanics biotribology bioresorbable chitosan/chitosan-nano-hydroxyapatite construct (OCC), implanted in an vitro porcine...
Haemophilia A (HA) is a blood clotting disorder caused by various genetic deficiencies in the factor VIII (FVIII) encoding F8 gene. Patients receiving FVIII replacement therapy are at risk of developing neutralizing antibodies (FVIII inhibitors) rendering ineffective. Immunological tolerance towards can be achieved through immune induction (ITI) protocols some patients but this lengthy and costly desensitization programme. Long-term eradication inhibitors HA could antigen-specific...
A human cadaveric specimen-specific knee model with appropriate soft tissue constraints was developed to appropriately simulate the biomechanical environment in knee, order pre-clinically evaluate and tribological performance of interventions. Four knees were studied a natural simulator under force control conditions anterior posterior (AP) tibial rotation (TR) axes, using virtual springs replicate function tissues. The most spring for each determined by comparing kinematic outputs terms AP...
No AccessJournal of Urology1 Jun 1987Modulation Motility in Reactivated Human Sperm Models William Sanderson, and John D. McConnell SandersonWilliam Sanderson More articles by this author , McConnellJohn View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)76006-5AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "Modulation Models." The Journal Urology, 137(6), p. 318A © 1987 American Urological Association...