A5020275475- Head and Neck Cancer Studies
- Advanced Radiotherapy Techniques
- Lung Cancer Diagnosis and Treatment
- Esophageal Cancer Research and Treatment
- Prostate Cancer Diagnosis and Treatment
- Medical Imaging Techniques and Applications
- Cancer Diagnosis and Treatment
- MRI in cancer diagnosis
- Esophageal and GI Pathology
- Management of metastatic bone disease
- Prostate Cancer Treatment and Research
- Head and Neck Surgical Oncology
- Gastric Cancer Management and Outcomes
- Oral health in cancer treatment
- Salivary Gland Tumors Diagnosis and Treatment
- Radiation Therapy and Dosimetry
- Hepatocellular Carcinoma Treatment and Prognosis
- Radiomics and Machine Learning in Medical Imaging
- Brain Metastases and Treatment
- Effects of Radiation Exposure
- Ear and Head Tumors
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Adrenal and Paraganglionic Tumors
- Breast Cancer Treatment Studies
- Cerebrovascular and Carotid Artery Diseases
Gifu University Hospital
2019-2025
Gifu University
2020-2023
Asahi University
2021
Aichi Cancer Center
2014-2019
Gifu Prefectural General Medical Center
2018-2019
Proton (Malaysia)
2011-2014
Southern Tohoku General Hospital
2011-2014
We examined the efficacy and toxicity of proton beam therapy (PBT) for treating advanced cholangiocarcinoma.The clinical data outcomes 28 cholangiocarcinoma patients treated with PBT between January 2009 August 2011 were retrospectively examined. The Kaplan-Meier method was used to estimate overall survival (OS), progression-free (PFS), local control (LC) rates, log-rank test analyze effects different treatment variables on survival. Acute late toxicities assessed using National Cancer...
Setting the echo time to zero allows for acquisition of bone images that were otherwise difficult obtain with conventional MRI and clear visualization CT-like MR images. This technique is mainly useful detecting compression fractures; however, studies examining tumours have been lacking. Furthermore, no reports date investigated usefulness evaluating before after radiotherapy (RT) tumours. Therefore, plain CT (T1/T2-weighted image MRI) performed under same conditions radiation therapy...
Abstract The effect of proton beam therapy ( PBT ) on various cancers is controversial. We aimed to evaluate the efficacy and safety with alternating chemoradiotherapy ACRT for patients stage I–III esophageal cancer. Two cycles systemic chemotherapy a continuous infusion 5‐fluorouracil (5‐ FU days 1–5 5h nedaplatin NDP day 6 were accompanied by thoracic irradiation using X‐ray . During first half treatment, X‐rays delivered prophylactic area. second beams used irradiate involved field. To...
High Charlson comorbidity index values have been reported to be associated with shorter overall survival in various types of cancer. We investigated whether were correlated patients resectable sinonasal tract squamous cell carcinoma.Seventy-nine carcinoma treated curative intent. The calculated by the summation weight scores 19 medical conditions (other than carcinoma) before treatment. rate was analyzed according Kaplan-Meier method. Univariate and multivariate analyses performed using...
Abstract Background The efficacy of intensity‐modulated radiotherapy (IMRT) for cervical esophageal cancer has not been determined. Methods Eighty patients with treated definitive chemoradiotherapy from 2002 to 2014 were analyzed. Overall survival (OS), failure patterns, and toxicity incidence compared between the IMRT (N = 32) 3D conformal (RT; N 48) groups. Results median follow‐up was 35.9 months. 3‐year OS IMRT, RT, total groups 81.6%, 57.2%, 66.6%, respectively. Pulmonary observed IMRT....
Evidence has suggested that radiation therapy with a lower dose per fraction may be reasonable option for the treatment of centrally located non-small cell lung cancer (NSCLC). The aim this study was to evaluate safety and efficacy two proton beam (PBT) protocols stage I NSCLC determine prognostic factors.This included patients clinically diagnosed NSCLC. Based on location tumor, one PBT administered. Patients peripherally tumors were given 66 Gy relative biological effectiveness (RBE) over...
Standard treatment for progressive gastric cancer with bleeding includes hemostatic radiotherapy (RT); however, the only prospective study using a fixed dose fractions during RT did not introduce re-irradiation. Therefore, we determined utility of including re-irradiation cancer.In this study, 31 patients and were treated an initial 20 Gy/5 whole stomach salvage 15 partial stomach. Patients achieving hemostasis, defined as stable hemoglobin level within 30 days following irradiation,...
Abstract Bone-modifying agents (BMAs) are frequently used for the treatment of bone metastases. Both BMA and radiation therapy (RT) effective; however, there few studies that have evaluated efficacy combination treatment. We effectiveness RT + in breast cancer-induced osteolytic metastasis as compared to alone. A total 43 lesions 25 patients were evaluated. The median follow-up period was 18 (range, 2–90) months. None treated with chemotherapy or molecular targeted drugs during evaluating...
The present study aimed to clarify the incidence and clinical outcomes of nasopharyngeal carcinoma (NPC) in Chubu region Japan from 2006 2015, compared with previous reports. A retrospective analysis was conducted based on medical records 40 hospitals located central Japanese main island, a population around 22.66 million individuals. This designed line two studies into NPC same area Japan. We recruited patients diagnosed across this over 10-year period (2006-2015) using questionnaire about...
To analyze the clinical outcome of concurrent chemoradiotherapy in superficial esophageal cancer patients.We retrospectively analyzed data for 123 patients with who received external beam radiotherapy without intracavitary brachytherapy plus systemic chemotherapy during 1998-2015. Elective nodal irradiation was not performed. The dosage to planning treatment volume 60 Gy 30 fractions. main measure overall survival.Patient characteristics were as follows: median age, 66 (41-83) years;...
In this retrospective cohort study, we evaluated the incidence of vascular events from carotid artery atherosclerosis after radiotherapy indication for laryngeal and hypopharyngeal cancer. From January 2007 to December 2016, investigated 111 laryngeal/hypopharyngeal cancer patients who underwent curative were followed up ≥1 year (median follow-up duration, 60 months). We atherosclerosis, defined as a transient ischemic attack or an atherothrombotic cerebral infarction, undergoing treatment...
A retrospective analysis was performed to evaluate the clinical efficacy of definitive chemoradiotherapy including intensity-modulated radiotherapy for patients with hypopharyngeal cancer. Previously untreated 204 cancer were treated chemoradiotherapy. Of note, 66–70 Gy delivered primary and involved nodes 36–54 prophylactic lymph node using standard fractionated radiotherapy. One hundred forty-six received induction chemotherapy as a larynx preservation strategy, followed by or without...
Intensity-modulated radiotherapy is useful for cervical oesophageal carcinoma (CEC); however, increasing low-dose exposure to the lung may lead radiation pneumonitis. Nevertheless, an irradiation technique that avoids lungs has never been examined due high difficulty of dose optimization. In this study, we efficacy helical tomotherapy can restrict beamlets passing virtual blocks during optimization computing (block plan) in reducing dose. Fifteen patients with CEC were analysed. The...
ObjectiveTo evaluate the clinical outcomes of intensity-modulated radiotherapy for patients with oropharyngeal carcinoma.
Abstract A low modulation factor ( MF ) maintaining a good dose distribution contributes to the shortening of delivery time and efficiency treatment plan in helical tomotherapy. The purpose this study was reduce using initial values upper limit . First, patients with head neck cancer (293 cases) or prostate (181 treated between June 2011 July 2015 were included analysis values. value defined as average actual value, UL according following equation: = 2 × standard deviation + Next, designed...
Nausea and vomiting are two of the most distressing adverse events cancer radiotherapy. The aim this study was to examine control rate risk factors associated with nausea in patients cervical receiving radiotherapy.This retrospective examined who received radiotherapy alone or concomitant cisplatin. Patients were not administered antiemetic premedication, while weekly cisplatin (40 mg/m2) therapy comprising granisetron dexamethasone. Risk for non-complete response (CR) identified using...
Abstract Background Radiobiological daily changes within tumors are considered to be quite different between stereotactic radiotherapy (SRT) (e.g., 50 Gy in 4 fractions) and conventional 60 30 fractions). We aim assess the optimal interval of irradiation SRT compare outcomes with at two- three-day intervals for patients one five brain metastases (BM). Methods This study is conducted as a multicenter open-label randomized phase II trial. Patients aged 20 or older BM, less than 3.0 cm...
<h3>Objective</h3> The aim of this study was to compare the outcomes and toxicities radical hysterectomy (RH) definitive chemoradiation (CRT) for International Federation Gynecology Obstetrics (FIGO) stage IIB cervical cancer. <h3>Materials Methods</h3> A retrospective analysis performed on FIGO patients who underwent RH with adjuvant radiotherapy (surgery group) or intended receive CRT (CRT group). distributions disease-free survival (DFS) overall (OS) were calculated using Kaplan-Meier...
Polymorphous low-grade adenocarcinoma is a rare malignant tumor that mainly occurs in salivary glands, particularly the hard palate. To date, surgery has been most commonly used treatment method with aim of achieving negative margins resection. Here, we report case 51-year-old woman who presented painless growing mass her oral cavity Rouviere's lymph node metastasis. Laboratory data showed severe anemia because bleeding from tumor. We inserted two catheters into bilateral external carotid...