Luíz Felipe Pinho Moreira

ORCID: 0000-0003-0179-4976
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About
Contact & Profiles
Research Areas
  • Cardiac Structural Anomalies and Repair
  • Cardiac Valve Diseases and Treatments
  • Cardiac pacing and defibrillation studies
  • Mechanical Circulatory Support Devices
  • Congenital Heart Disease Studies
  • Transplantation: Methods and Outcomes
  • Cardiomyopathy and Myosin Studies
  • Aortic Disease and Treatment Approaches
  • Cardiac Arrhythmias and Treatments
  • Cardiac Ischemia and Reperfusion
  • Cardiovascular Function and Risk Factors
  • Cardiac and Coronary Surgery Techniques
  • Cardiac, Anesthesia and Surgical Outcomes
  • Pulmonary Hypertension Research and Treatments
  • Science and Science Education
  • Pharmaceutical industry and healthcare
  • Tissue Engineering and Regenerative Medicine
  • Organ Donation and Transplantation
  • Organ Transplantation Techniques and Outcomes
  • Cardiac electrophysiology and arrhythmias
  • Coronary Artery Anomalies
  • Ethics in Clinical Research
  • Cardiac Arrest and Resuscitation
  • Electrospun Nanofibers in Biomedical Applications
  • Meta-analysis and systematic reviews

Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2016-2025

Instituto do Coração
2009-2025

Universidade de São Paulo
2015-2024

University of Tennessee Health Science Center
2020-2024

Universidade Federal de Pernambuco
2024

Universidade de Brasília
2024

University of Arizona
2024

Universidade Federal do Pará
2023

Health Affairs
2022

Instituto Evandro Chagas
2021

Correspondencia: Luiz Felipe P. Moreira • Av. Dr. Eneas Carvalho Aguiar, 44 2o andar, Bloco 2, Sala 13 Cerqueira Cesar 05403-000 Sao Paulo, SP Brasil Email: lfelipe@cardiol.br Los Arquivos Brasileiros de Cardiologia han sido a lo largo mas 60 anos uno los principales medios divulgacion las investigaciones cientificas en el area enfermedades cardiovasculares nuestro Pais. Figurando todas bases datos internacionales y siendo vehiculado tres idiomas con acceso libre su contenido integral traves...

10.1590/s0066-782x2010001100001 article ES cc-by-nc Arquivos Brasileiros de Cardiologia 2010-07-01

Esta atualizacao da Diretriz de Insuficiencia Cardiaca Cronica (IC) - 2012 surge para reavaliar as recomendacoes atraves uma avaliacao criteriosa das pesquisas (considerando-se a qualidade dos estudos), fundamental que se atinja esse proposito. Para tanto, foi dada enfase ao efeito em desfechos morte, CONSORT (Consolidated Standards of Reporting Trials), descricao qualitativa e quantitativa otimizacao medicacao, populacao realmente incluida, metanalises somente estudos CONSORT,...

10.1590/s0066-782x2012000700001 article PT cc-by-nc Arquivos Brasileiros de Cardiologia 2012-07-01

The effectiveness of heart failure disease management programs in patients under cardiologists' care over long-term follow-up is not established.We investigated the effects a program with repetitive education and telephone monitoring on primary (combined death or unplanned first hospitalization quality-of-life changes) secondary end points (hospitalization, death, adherence). REMADHE [Repetitive Education Monitoring for ADherence Heart Failure] trial randomized, prospective, parallel...

10.1161/circheartfailure.107.744870 article EN Circulation Heart Failure 2008-05-29

Forty-four patients seen between 1975 and 1985 with anorectal strictures complicating Crohn's disease have been reviewed to determine the natural history outcome of surgical treatment. Proctitis was present in 98 per cent, 93 cent had sever perianal disease. The site rectal 22, anal 15 11 (4 a stricture at 2 sites). Initial treatment by excision alone 6, dilatation 33, 5 needed no all. Single effective 15, 8 required two dilatations 10 repeated necessary. Proctocolectomy eventually 19...

10.1002/bjs.1800750711 article EN British journal of surgery 1988-07-01

Decellularized-organ-derived extracellular matrix (dECM) has been used for many years in tissue engineering and regenerative medicine. The manufacturing of hydrogels from dECM allows to make use the pro-regenerative properties ECM and, simultaneously, shape material any necessary way. objective present project was investigate differences between cardiovascular tissues (left ventricle, mitral valve, aorta) with respect generating their interaction cells 2D 3D. left aorta porcine hearts were...

10.3389/fbioe.2020.00520 article EN cc-by Frontiers in Bioengineering and Biotechnology 2020-05-29

Disclosure of potential conflicts interest (COIs) is used by biomedical journals to guarantee credibility and transparency the scientific process. Conflict disclosure, however, not systematically nor consistently dealt with journals. Recent joint editorial efforts paved way towards implementation uniform vehicles for COI disclosure. This paper provides a comprehensive perspective on classical COI-related issues. New insights into current policies practices among European Society Cardiology...

10.1093/eurheartj/ehr464 article EN European Heart Journal 2012-03-01

The number of Brazilian scientific publications in the field Cardiology and Cardiovascular Sciences international indexing journals, different from other areas Medicine, has remained largely stable over past eight years. This situation does not reflect significant increase senior researchers studies carried out several fields activity that constitute our medical specialty. We currently observe development Postgraduate Programs, as well opening new research centers focused on study...

10.5935/abc.20160109 article EN cc-by-nc Arquivos Brasileiros de Cardiologia 2016-01-01

The purpose of this study was to prospectively assess the effect dynamic cardiomyoplasty in patients with symptomatic chronic heart failure. Since first procedure performed 1985, has been developed for use aging population countries made failure a growing public health concern. Heart transplantation is appropriate or available only small proportion these because limited donor supply. Effective alternatives are needed. Eight centers North and South America 68 procedures between May 1991...

10.1016/s0735-1097(96)00298-7 article EN cc-by-nc-nd Journal of the American College of Cardiology 1996-11-01

Abstract Transforming growth factor-β1 (TGF-β1) is a potent inducer of fibroblast to myofibroblast differentiation and contributes the pro-fibrotic microenvironment during cardiac remodeling. Fibroblast factor-2 (FGF-2) factor secreted by adipose tissue-derived stromal cells (ASC) which can antagonize TGF-β1 signaling. We hypothesized that TGF-β1-induced abrogated FGF-2 ASC conditioned medium (ASC-CMed). Our experiments demonstrated treatment-induced into myofibroblasts, as evidenced...

10.1038/s41598-018-34747-3 article EN cc-by Scientific Reports 2018-11-05

In this study, we investigated the acid (HCl) and alkali (KOH) chemical activation of açaí seeds (Euterpe Oleraceae, Mart.) pre-treatment before pyrolysis at temperatures 350–450 °C in order to assess how reactions proceed when affected by temperature. Chemical composition bio-oil aqueous phase were determined GC-MS FT-IR. The bio-char is characterized XRD. For with KOH, XRD analysis identified presence Kalicinite (KHCO3), dominant crystalline bio-char, while an amorphous was bio-chars for...

10.3390/en16073162 article EN cc-by Energies 2023-03-31

Doxorubicin-induced cardiomyopathy (DOX-IC) is a significant and common complication in patients undergoing chemotherapy, leading to cardiac remodeling reduced heart function. We hypothesized that the intrapericardial injection of hydrogels derived from decellularized extracellular matrix (dECM) loaded with adipose tissue-derived stromal cells (ASC) their secretome dampens or reverses progression DOX-IC. DOX-IC was induced Wistar male rats through ten weekly intra-peritoneal injections...

10.1038/s41598-025-87939-z article EN cc-by-nc-nd Scientific Reports 2025-01-28
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