- Congenital Heart Disease Studies
- Pulmonary Hypertension Research and Treatments
- Cardiac Structural Anomalies and Repair
- Cardiac Valve Diseases and Treatments
- Cardiac Arrhythmias and Treatments
- Coronary Artery Anomalies
- Congenital heart defects research
- Cardiac pacing and defibrillation studies
- Infective Endocarditis Diagnosis and Management
- Coronary Interventions and Diagnostics
- Vascular anomalies and interventions
- Cardiomyopathy and Myosin Studies
- Trypanosoma species research and implications
- Congenital Diaphragmatic Hernia Studies
- Streptococcal Infections and Treatments
- Tracheal and airway disorders
- Cardiac tumors and thrombi
- Viral Infections and Immunology Research
- Cardiovascular and Diving-Related Complications
- Cardiovascular Function and Risk Factors
- Mechanical Circulatory Support Devices
- Atrial Fibrillation Management and Outcomes
- Cardiovascular Effects of Exercise
- Cardiovascular Issues in Pregnancy
- Public Health in Brazil
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2015-2025
Universidade de São Paulo
2015-2024
Instituto do Coração
2010-2023
Hospital do Coração
1996-2023
Associação Fundo de Incentivo à Pesquisa
2009-2017
Centro Universitário das Faculdades Metropolitanas Unidas
2005-2012
University of Virginia
2011
Cambridge University Press
2009-2011
Versus Arthritis
2011
Universidade Estadual de Campinas (UNICAMP)
2008
Clinicians working in the field of congenital and paediatric cardiology have long felt need for a common diagnostic therapeutic nomenclature coding system with which to classify patients all ages acquired cardiac disease. A cohesive comprehensive nomenclature, suitable setting global standard multicentric analysis outcomes stratification risk, has only recently emerged, namely, The International Paediatric Congenital Cardiac Code. This review, will give an historical perspective on...
Background— Fetal atrioventricular (AV) block is an uncommon lesion with significant mortality. Because of the rarity this disorder, natural course, extensive evaluation untreated fetuses, and late follow-up remain unclear. Methods Results— Of 116 consecutive cases fetal AV studied from 1988 to 2006, only 1 was terminated, 75% were live births. Fifty-nine associated major structural heart disease, mainly left atrial isomerism (n=40), 26% neonatal survivors. 57 fetuses normal cardiac anatomy,...
Abstract An internationally approved and globally used classification scheme for the diagnosis of CHD has long been sought. The International Paediatric Congenital Cardiac Code (IPCCC), which was produced maintained by Society Nomenclature Heart Disease (the Society), is widely, but spawned many “short list” versions that differ in content depending on user. Thus, efforts to have a uniform identification patients with using single up-to-date coordinated nomenclature system continue be...
Abstract Substantial progress has been made in the standardization of nomenclature for paediatric and congenital cardiac care. In 1936, Maude Abbott published her Atlas Congenital Cardiac Disease, which was first formal attempt to classify heart disease. The International Paediatric Code ( IPCCC ) is now utilized worldwide most recently become component Eleventh Revision Classification Diseases ICD-11 ). recent publication 2017. This manuscript provides an updated 2021 version . Society...
Interventional cardiology for paediatric and congenital cardiac disease is a relatively young rapidly evolving field. As the profession begins to establish multi-institutional databases, universal system of nomenclature necessary field interventional disease. The purpose this paper present results efforts International Society Nomenclature Paediatric Congenital Heart Disease cardiovascular catheterisation disease, focusing both on procedural complications associated with cardiology. This...
Background Leptospirosis is a re-emerging zoonosis with protean clinical manifestations. Recently, the importance of pulmonary hemorrhage as lethal complication this disease has been recognized. In present study, five human necropsies leptospirosis (Weil's syndrome) extensive manifestations were analysed, and antibodies expressed in blood vessels cells involved ion water transport used, seeking to better understand pathophysiology lung injury associated disease. Principal Findings Prominent...
Standardization of the diagnostic routine for children with congenital heart disease associated pulmonary arterial hypertension (PAH‐CHD) is crucial, in particular since inappropriate assignment to repair cardiac lesions (e.g., surgical patients elevated vascular resistance) may be detrimental and poor outcomes. Thus, members Congenital Heart Disease Pediatric Task Forces Pulmonary Vascular Research Institute decided conduct a survey aimed at collecting expert opinion from different...
Substantial progress has been made in the standardization of nomenclature for paediatric and congenital cardiac care. In 1936, Maude Abbott published her Atlas Congenital Cardiac Disease, which was first formal attempt to classify heart disease. The International Paediatric Code (IPCCC) is now utilized worldwide most recently become component Eleventh Revision Classification Diseases (ICD-11). recent publication IPCCC 2017. This manuscript provides an updated 2021 version IPCCC.The Society...
Doxorubicin-induced cardiomyopathy (DOX-IC) is a significant and common complication in patients undergoing chemotherapy, leading to cardiac remodeling reduced heart function. We hypothesized that the intrapericardial injection of hydrogels derived from decellularized extracellular matrix (dECM) loaded with adipose tissue-derived stromal cells (ASC) their secretome dampens or reverses progression DOX-IC. DOX-IC was induced Wistar male rats through ten weekly intra-peritoneal injections...
Abstract Interventional cardiology for paediatric and congenital cardiac disease is a relatively young rapidly evolving field. As the profession begins to establish multi-institutional databases, universal system of nomenclature necessary field interventional disease. The purpose this paper present results efforts International Society Nomenclature Paediatric Congenital Heart Disease cardiovascular catheterisation disease, focusing both on procedural complications associated with cardiology....
To investigate the role played by Trypanosoma cruzi in pathogenesis of chronic chagasic cardiopathy, myocardiums 12 hearts from individuals who had this condition were mapped detail. Attempts made to associate histopathological lesions observed with presence parasitic antigens affected tissue. Samples 26 regions each heart submitted histological analysis and immunostained for T. cruzi. All cases showed at least one positive region antigens, but quantity antigen detected varied greatly. The...
This paper reports what is apparently the first observation of Mycoplasma pneumoniae in association with Chlamydia thrombosed ruptured atheromas. We performed electron microscopy and situ hybridization specimens from three patients who died acute myocardial infarction. These had typical symptoms ischemic syndrome. Mycoplasmas were present mainly lipid core plaque. Vulnerable atheromas are rich cholesterol may favor growth mycoplasmas, only microorganisms that require for survival. suggest...
OBJECTIVE: To verify the possible role of adventitial inflammation in atherosclerotic plaque vulnerability and coronary artery remodelling. METHODS: We compared mean numbers lymphocytes adventitia ruptured thrombosed stable equi-stenotic segments 34 patients who died due to acute myocardial infarction. also analysed microvessels, fibrosis external elastic membrane. RESULTS: In adventitia, microvessels/mm² were 69.5±88.3 60.9± 32.1 culprit lesions 16.4 ± 21.1 44.3±16.1 (p<0.05); within...
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MeCP2 plays a critical role in interpreting epigenetic signatures that command chromatin conformation and regulation of gene transcription. In spite MeCP2's ubiquitous expression, its functions have always been considered the context brain physiology. this study, we demonstrate alterations normal pattern expression cardiac skeletal tissues are detrimental for development. Overexpression mouse heart leads to embryonic lethality with septum hypertrophy dysregulated tissue produces severe...