A5047476753- Advanced Chemical Sensor Technologies
- Gas Sensing Nanomaterials and Sensors
- Biosensors and Analytical Detection
- Olfactory and Sensory Function Studies
- Biochemical Analysis and Sensing Techniques
- Analytical Chemistry and Chromatography
- Analytical Chemistry and Sensors
- Mass Spectrometry Techniques and Applications
- Insect Pheromone Research and Control
- Metabolomics and Mass Spectrometry Studies
- Vibrio bacteria research studies
- Salmonella and Campylobacter epidemiology
- Advanced Sensor and Energy Harvesting Materials
- Yersinia bacterium, plague, ectoparasites research
- Antimicrobial Peptides and Activities
- Identification and Quantification in Food
- Conducting polymers and applications
- SARS-CoV-2 detection and testing
- interferon and immune responses
- Neuroscience and Neural Engineering
- Immune Response and Inflammation
- Aquaculture disease management and microbiota
- Gene expression and cancer classification
- Heavy Metal Exposure and Toxicity
- Parkinson's Disease Mechanisms and Treatments
Technion – Israel Institute of Technology
2016-2025
Tumour growth is accompanied by gene and/or protein changes that may lead to peroxidation of the cell membrane species and, hence, emission volatile organic compounds (VOCs). In this study, we investigated ability a nanosensor array discriminate between breath VOCs characterise healthy states and most widespread cancer in developed world: lung, breast, colorectal, prostate cancers. Exhaled alveolar was collected from 177 volunteers aged 20–75 years (patients with colon, cancers controls)....
This article reports on a noninvasive approach in detecting and following-up individuals who are at-risk or have an existing COVID-19 infection, with potential ability to serve as epidemic control tool. The proposed method uses developed breath device composed of nanomaterial-based hybrid sensor array multiplexed detection capabilities that can detect disease-specific biomarkers from exhaled breath, thus enabling rapid accurate diagnosis. An exploratory clinical study this was examined...
Upper digestive endoscopy with biopsy and histopathological evaluation of the material is standard method for diagnosing gastric cancer (GC). However, this procedure may not be widely available screening in developing world, whereas developed countries frequently used without major clinical gain. There a high demand simple non-invasive test selecting individuals at increased risk that should undergo endoscopic examination. Here, we studied feasibility nanomaterial-based breath identifying GC...
A cross-reactive array of polycyclic aromatic hydrocarbons and single wall carbon nanotube bilayers was designed for the detection volatile organic compounds (tentatively, hexanal 5-methyl-undecane) that identify presence disease in exhaled breath patients with multiple sclerosis. The sensors showed excellent discrimination between hexanal, 5-methyl-undecane, other confounding compounds. Results obtained from a clinical study consisting 51 volunteers could discriminate sclerosis healthy...
Analysis of volatile organic compounds (VOCs) is a promising approach for non-invasive, fast and potentially inexpensive diagnostics. Here, we present new methodology profiling the body chemistry by using fraction molecules in various fluids. Using mass spectrometry cross-reactive nanomaterial-based sensors array, demonstrate that simultaneous VOC detection from breath skin would provide complementary, non-correlated information body's metabolites profile. Eventually with further wide...
The current review provides an assessment of the exhalation kinetics volatile organic compounds (VOCs) that have been linked with cancer. Towards this end, we evaluate various physicochemical properties, such as 'breath:air' and 'blood:fat' partition coefficients, 112 VOCs suggested over past decade potential markers With these data, show cancer VOC concentrations in blood fat span 12 8 orders magnitude, respectively, order to provide a specific counterpart concentration exhaled breath...
To the Editor: Detecting active tuberculosis (TB) remains a major global public health challenge [1]. The tuberculin skin test does not distinguish latent from TB [2]. interferon-γ release assays have similar limitations [3]. Acid-fast bacilli staining of sputum has high false-negative rate (up to 50%) [4]. Nucleic acid amplification tests (NAATs), such as GeneXpert MTB/RIF (Cepheid, Sunnyvale, CA, USA), are accurate but require good infrastructure and necessity obtain quality sample,...
Sodium is a prominent prognostic biomarker for assessing health status, such as dysnatremia. As of now, detection and monitoring sodium levels in the human body carried out by means laborious bulky laboratory equipmentand/or offline analysis various fluids. Herein, an innovative stretchable, skin-conformal fast-response microneedle extended-gate FET biosensor reported real-time interstitial fluids minimally invasive along with high sensitivity, low limit detection, excellent...
Cardiac monitoring after heart surgeries is crucial for health maintenance and detecting postoperative complications early. However, current methods like rigid implants have limitations, as they require performing second complex removal, increasing infection inflammation risks, thus prompting research improved sensing technologies. Herein, we introduce a nanosensor platform that biodegradable, biocompatible, integrated with multifunctions, suitable use cardiac monitoring. The device has two...
Multiple sclerosis (MS) is the most common chronic neurological disease affecting young adults. MS diagnosis based on clinical characteristics and confirmed by examination of cerebrospinal fluids (CSF) or magnetic resonance imaging (MRI) brain spinal cord both. However, neither current diagnostic procedures are adequate as a routine tool to determine state. Thus, biomarkers needed. In study, novel approach that could meet these expectations presented. The noninvasive analysis volatile...
ABSTRACT Vibrio cholerae is the etiological agent of cholera. Its natural reservoir aquatic environment. To date, practical typing V. mainly serological and requires about 200 antisera. Simple sequence repeats (SSR), also termed VNTR (for variable number tandem repeats), provide a source high genomic polymorphism used in bacterial typing. Here we describe an SSR-based method that combines variation highly mutable SSR loci, with shorter, relatively more stable mononucleotide repeat (MNR) for...
Breath-gas analysis has demonstrated that concentration profiles of volatile organic compounds (VOCs) could be used for detecting a variety diseases, among them gastric cancer (GC) and peptic ulcer disease (PUD). Here, we explore how geographical variation affects the disease-specific changes in chemical composition breath samples, as compared to control states (less severe conditions). Alveolar exhaled samples from 260 patients were collected at two remotely different geographic locations...
The aim was to derive a breath-based classifier for gastric cancer using nanomaterial-based sensor array, and validate it in large screening population.A new training algorithm the diagnosis of derived from previous breath samples patients with healthy controls clinical setting, validated blinded manner population.The 99 342 controls, population 726 people. calculated set had 82 per cent sensitivity, 78 specificity 79 accuracy. correctly classified all three 570 723 cancer-free population,...