A5009171979- Blood properties and coagulation
- Breastfeeding Practices and Influences
- Digestive system and related health
- Infant Nutrition and Health
- Pharmacological Effects of Natural Compounds
- Virus-based gene therapy research
- Meat and Animal Product Quality
- Reproductive Health and Contraception
- Diet, Metabolism, and Disease
- Carcinogens and Genotoxicity Assessment
- Liver Disease Diagnosis and Treatment
- Veterinary Oncology Research
- Adipose Tissue and Metabolism
- Animal Diversity and Health Studies
- Reproductive System and Pregnancy
- Eicosanoids and Hypertension Pharmacology
- Ukraine: War, Education, Health
- Maternal and Perinatal Health Interventions
- Skin and Cellular Biology Research
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Protease and Inhibitor Mechanisms
- Muscle metabolism and nutrition
- Protein purification and stability
- Receptor Mechanisms and Signaling
Cairo University
2001-2024
King Abdulaziz University
2012-2020
Tokyo Institute of Technology
1994-2001
Eisai (Japan)
1995
National Water Research Center
1969-1970
Al-Azhar University
1969
Journal Article Elastase Inhibitor Elafin Is a New Type of Proteinase Which Has Transglutaminase-Mediated Anchoring Sequence Termed "Cementoin" Get access Kiyomitsu Nara, Nara *Department Biological Sciences, Tokyo Institute TechnologyNagatsuta 4259, Midori-ku, Yokohama 227 Search for other works by this author on: Oxford Academic PubMed Google Scholar Shiho Ito, Ito Teizo Yohko Suzuki, Suzuki Magdy A. Ghoneim, Ghoneim Shinro Tachibana, Tachibana **Tsukuba Research Laboratories, Eisai Co.,...
Abstract The current study was carried out to evaluate the potency of curcumin and chlorophyllin as natural antioxidants reduce oxidative stress markers induced by cyclophosphamide (CP) benzo[a]pyrene [B(a)P] which were used free radical inducers. For this purpose, 126 male albino rats used. animals assigned into 4 main groups: negative control group; oxidant-treated group (subdivided two subgroups: cyclophosphamide- treated benzo[a]pyrene-treated group); curcumin-treated...
Excessive production of free radicals can result in tissue damage, which mainly involves generation hydroxyl radical and other oxidants. Such radical-induced cell damage appears to play a major role the pathogenesis many diseases. Probiotics have been used therapeutically modulate immunity, improve digestive processes, lower cholesterol, treat rheumatoid arthritis, prevent cancer. The proposed research was designed evaluate changes oxidative antioxidative profile addition metabolic-related...
This study aimed to evaluate the levels of thyroid hormones and lactate dehydrogenase (LDH) isoenzymes in obese and/or diabetic patients.Forty male subjects categorized into four equal groups; group 1: Non control subjects, 2: Subjects suffering from type 2 diabetes mellitus (T2DM), 3: Obese (BMI ≥ 30 kg/m2) 4: thatwere had (T2DM). Liver, kidney, lipid, hormones, total LDH were determined.There was a significant increase TSH level (p<0.001) as compared with highly obtained groups versus...
Background: The current trend globally is the utilization of natural products as therapeutic agents given its minimum side effects.
 leaves Stevia contain several active ingredient compounds such rebaudioside. extract have been used for many
 purposes. Active oxygen radicals can induce base modifications, DNA breakage, and intracellular protein crosslink's. This study was
 done to evaluate potential stevia antibacterial antioxidants actions.
 Materials methods:...
Probiotics are known as living, nonpathogenic microorganisms that colonize the intestine and provide benefit to host. The present study aims measure one important energy metabolism-related enzyme activity in blood of rabbits fed on probiotics recommended concentration. In addition, it also for evaluation expression level lactate dehydrogenase (LDH) using reverse transcriptase-polymerase chain reaction (RT-PCR) technique. Two groups used: control group receiving normal standardized diet other...
BackgroundNephrotoxicity occurs as a side effect of treating solid tumor with single dose cisplatin anticancer drug because the increase in oxidative stress. In this study, free radicals scavenging capacity thymoquinone (TQ) and vitamin E were tested to decrease stress resulted from treatment male rats.Material methodsSixty rats divided into 6 groups. The 1st group was negative control (G1) intraperitoneally injected only once saline 40 20 mg/kg body weight (b.w.) four 2nd (G2) positive...
The effects of glucagon injection and infusion glucose volatile fatty acids were studied in one-humped camels. Twenty adult male camels divided into four equal groups. first group was infused with physiological saline served as a control. second injected single dose glucagon, the third (50%) sterile saline, fourth acid (VFA) mixture. In first, groups, sampling performed before beginning infusions (control time), at 15, 30, 60 120 min post-infusion. Plasma concentrations monitored 5, 10, 20,...
SUMMARY Histidine-tagged green fluorescent protein (His 6 -Xpress-GFP), a widely used probe, was found to be good substrate for transglutaminase, an enzyme that catalyzes covalent crosslinking of proteins. GFP alone did not serve as but its derivative His -Xpress-GFP readily crosslinked through the Gln and Lys residues present in short N-terminal extension -Xpress). sensitive enough detect transglutaminase activity guinea pig liver homogenates. The could also staining on histological tissue...
Summary: The ETB receptor has been found to be predominantly expressed in the vascular endothelium of various bovine tissues by immunostaining with a highly specific antiserum that does not cross-react ETA. examined include lung, trachea, kidney, adrenal gland, pituitary and cerebellum. widespread localization endothelial lining suggests there is an ETB-mediated autocrine system endothelin, which plays important role regulation functions cells.
The primary and gene structures tissue distribution of porcine SPAI-2, a protein that belongs to the WAP superfamily has sodium-potassium ATPase inhibitory activity, were determined by molecular cloning Northern analysis. A full-length cDNA clone was isolated from duodenum library. insert encoded polypeptide 187 amino acids, which is composed three domains: hydrophobic presequence 21 prosegment 105 acids ending with Asp126, mature SPAI-2 sequence 61 beginning Pro127. contained 16 repeats...
Mutations in the p53 tumour suppressor gene have been associated with chemical carcinogens. Natural antimutagens are promising modulators for reducing cancer risk. The present study was carried out to assess protective efficacy of some natural against alterations. We investigated ability curcumin (100 mg/kg BW) and chlorophyllin (3 pretreatment, three times per week successive weeks, inhibit mutations induced by intraperitoneal injection a single dose 40 BW cyclophosphamide (CP). Forty male...
SPAI, originally isolated as a sodium/potassium-ATPase inhibitor and now considered to be proteinase of unknown specificity based on its similarity elafin (an elastase inhibitor), is new type plasma protein that has transglutaminase substrate domain, which serves an anchoring sequence covalently cross-linked at target sites. To determine the source we carried out in situ hybridization immunohistochemistry using antisense cRNA probe antiserum against recombinant respectively. Since previous...
Beim männlichen Blasenkarzinompatienten hat der orthotope Blasenersatz während letzten Jahre unbestreitbar weiter an Popularität gewonnen. Die Gründe sind sicherlich vielschichtig. Einige wenige seien beispielhaft herausgehoben: