A5055991332- Viral Infections and Vectors
- Vector-borne infectious diseases
- Mosquito-borne diseases and control
- Vector-Borne Animal Diseases
- Insect and Pesticide Research
- Dermatological diseases and infestations
- Insect-Plant Interactions and Control
- Malaria Research and Control
- Physiological and biochemical adaptations
- Insect behavior and control techniques
- Insect and Arachnid Ecology and Behavior
- Insect symbiosis and bacterial influences
- Neurobiology and Insect Physiology Research
- Insect Resistance and Genetics
- Toxin Mechanisms and Immunotoxins
- Diphtheria, Corynebacterium, and Tetanus
- Forest Insect Ecology and Management
- Entomological Studies and Ecology
- Insect Pest Control Strategies
- Virology and Viral Diseases
- Plant Virus Research Studies
- Public Health Policies and Education
- Viral Infections and Outbreaks Research
- Forensic Entomology and Diptera Studies
- Microbial infections and disease research
Connecticut Agricultural Experiment Station
2015-2025
Mayo Clinic Hospital
2019
Queen Elizabeth Hospital Birmingham
2018
Mayo Clinic in Arizona
2016-2018
Yale University
1997-2018
University of Newcastle Australia
2016
University of Tennessee at Chattanooga
2015
Experimental Station
2013-2014
University of Chester
2010-2013
University of Minnesota
1982-2011
An up-to-date handbook on conceptual and methodological issues relevant to the study of industrial organizational behavior. Chapters contributed by leading experts from academic business communities cover substantive at both individual level, in theoretical practical terms.
The mid‐shaft circumferences of the humerus and femur are closely related to body weight in living terrestrial vertebrates. Because these elements frequently preserved subfossil fossil vertebrate skeletal materials, relationship can be used estimate extinct When allometric equations applied dinosaurs, weights calculated for some giant sauropods ( Brachiosaurus ) found lighter than previous estimates.
Abstract To evaluate the role of Culex mosquitoes as enzootic and epidemic vectors for WNV, we identified source vertebrate blood by polymerase chain reaction amplification sequencing portions cytochrome b gene mitochondrial DNA. All Cx. restuans 93% pipiens acquired from avian hosts; salinarius fed frequently on both mammals (53%) birds (36%). Mixed-blood meals were detected in 11% 4% pipiens, respectively. American robin was most common (38%) (37%). crow represented <1% none restuans....
Effects of starvation were investigated in two specices spiders to gain insight on how these predators deal with an unpredictable food supply. Comparison weights and body dimensions individuals from field populations those known nutritional status showed that lack is a problem for both species. Adult survival times under conditions averaged 208 days the wolf spider, Lycosa lenta, 276 cribellate web—builder, Filistata hibernalis. Potential adult life spans fed estimated be 305 L. lenta...
Outer surface protein C (OspC) is a differentially expressed major lipoprotein of Borrelia burgdorferi. ospC swiftly upregulated when spirochetes leave the Ixodes scapularis tick gut, migrate to salivary gland, and exit arthropod vector. Here we show that OspC strongly binds suggesting role for in spirochete adherence this tissue. In vivo studies using murine model Lyme borreliosis showed while F(ab)2 fragments did not influence either viability or gene expression, they interfere with B....
West Nile (WN) virus, a mosquito-transmitted virus native to Africa, Asia, and Europe, was isolated from two species of mosquitoes, Culex pipiens Aedes vexans , brain tissues 28 American crows, Corvus brachyrhynchos one Cooper's hawk, Accipiter cooperii in Connecticut. A portion the genome isolates four different hosts sequenced analyzed by comparative phylogenetic analysis. Our Connecticut were similar another most closely related WN Romania (2.8 3.6 percent difference). If established...
Outer surface protein C (OspC) is a differentially expressed major lipoprotein of Borrelia burgdorferi. ospC swiftly upregulated when spirochetes leave the Ixodes scapularis tick gut, migrate to salivary gland, and exit arthropod vector. Here we show that OspC strongly binds suggesting role for in spirochete adherence this tissue. In vivo studies using murine model Lyme borreliosis showed while F(ab)2 fragments did not influence either viability or gene expression, they interfere with B....
Two hundred and ten isolations of West Nile virus (WNV) were obtained from 17 mosquito species in six genera statewide surveillance conducted Connecticut June through October, 1999–2003. Culex pipiens (86), salinarius (32), restuans (26), Culiseta melanura Aedes vexans (12) implicated as the most likely vectors WNV region based on isolation data. was abundant July September is involved early season enzootic transmission late epizootic amplification wild bird populations. Epidemic to humans...
New data on the allometric relationship of skeletal mass to body birds and mammals indicate that avian skeleton is not proportionately lighter than mammals. Pneumatization may make some bones lighter, but leg are more robust those This results in an internal redistribution rather a reduction mass.
Borrelia burgdorferi outer surface protein (Osp) A has been used as a Lyme disease vaccine that blocks transmission: OspA antibodies of immune hosts enter ticks during blood feeding and destroy spirochetes before transmission to the host can occur. B. produce in gut unfed Ixodes scapularis ticks, many repress production process. This preferential expression suggests may have an important function vector. Here we show mediates spirochete attachment tick by binding I. protein. The domains...
Borrelia burgdorferi, the causative agent of Lyme disease, was isolated from liver a passerine bird, Catharus fuscescens (veery), and larval Ixodes dammini (tick) feeding on Pheucticus ludovicianus (rose-breasted grosbeak) Geothlypis trichas (common yellowthroat). In indirect immunofluorescence antibody tests, isolates reacted with polyclonal monoclonal (H5332) antibodies. Studies DNA composition veery isolate strain cultured an I. larva indicated that both were B. burgdorferi not anserina...
In the United States, Ixodes scapularis ticks overwinter in Northeast and Upper Midwest transmit agent of human granulocytic anaplasmosis, Anaplasma phagocytophilum, among other pathogens. We now show that presence A. phagocytophilum I. increases their ability to survive cold. identified an antifreeze glycoprotein, designated IAFGP, demonstrated via RNAi knockdown studies importance IAFGP for survival a cold environment. Transfection also increased viability yeast cells subjected...
Abstract West Nile (WN) virus causes fatal meningoencephalitis in laboratory mice, thereby partially mimicking human disease. Using this model, we have demonstrated that mice deficient γδ T cells are more susceptible to WN infection. TCRδ−/− elevated viral loads and greater dissemination of the pathogen CNS. In wild-type expanded significantly during infection, produced IFN-γ ex vivo assays, enhanced perforin expression by splenic cells. Adoptive transfer reduced susceptibility these virus,...
Dengue virus (DENV), a flavivirus of global importance, is transmitted to humans by mosquitoes. In this study, we developed in vitro and vivo models saliva-mediated enhancement DENV infectivity. Serine protease activity Aedes aegypti saliva augmented infectivity proteolyzing extracellular matrix proteins, thereby increasing viral attachment heparan sulfate proteoglycans inducing cell migration. A serine inhibitor reduced vivo, marked 100-fold reduction load murine lymph nodes. screen...