- Advanced Radiotherapy Techniques
- Lung Cancer Diagnosis and Treatment
- Glioma Diagnosis and Treatment
- Management of metastatic bone disease
- Medical Imaging Techniques and Applications
- Meningioma and schwannoma management
- Hepatocellular Carcinoma Treatment and Prognosis
- Brain Metastases and Treatment
- Vascular Malformations Diagnosis and Treatment
- Radiation Therapy and Dosimetry
- Head and Neck Cancer Studies
- Advances in Oncology and Radiotherapy
- Lung Cancer Treatments and Mutations
- Lung Cancer Research Studies
- Radiation Dose and Imaging
- Endometrial and Cervical Cancer Treatments
- Effects of Radiation Exposure
- Pituitary Gland Disorders and Treatments
- Radiomics and Machine Learning in Medical Imaging
- Advanced X-ray and CT Imaging
- Hematopoietic Stem Cell Transplantation
- Nonmelanoma Skin Cancer Studies
- Cancer Diagnosis and Treatment
- Dermatologic Treatments and Research
- Renal cell carcinoma treatment
University of Ilorin
2025
Texas Tech University Health Sciences Center
2017-2024
Texas Tech University
2017-2024
University Hospital and Clinics
2006-2024
University Medical Center
2006-2024
The University of Texas Southwestern Medical Center
2011-2021
Southwestern Medical Center
2009-2020
Covenant Health System
2019
Radiation Oncology Associates
2006-2016
Simmons University
2015
Surgical resection is standard therapy in stage I non-small-cell lung cancer (NSCLC); however, many patients are inoperable due to comorbid diseases. Building on a previously reported phase trial, we carried out prospective II trial using stereotactic body radiation (SBRT) this population.Eligible included clinically staged T1 or T2 (< = 7 cm), N0, M0, biopsy-confirmed NSCLC. All had medical problems that precluded lobectomy. SBRT treatment dose was 60 66 Gy total three fractions during 1 2...
Patients with stage IV non-small-cell lung cancer (NSCLC) who progress through first-line therapy have poor progression-free survival (PFS) and overall (OS), most commonly failing in original sites of gross disease. Cytoreduction stereotactic body radiation (SBRT) may help systemic agents delay relapse.Patients our single arm phase II study had NSCLC no more than six extracranial disease failed early chemotherapy were able to receive SBRT concurrent erlotinib until progression. After...
Abstract Background Advanced radiotherapeutic treatment techniques limit the cognitive morbidity associated with whole-brain radiotherapy (WBRT) for brain metastasis through avoidance of hippocampal structures. However, achieving durable intracranial control remains challenging. Methods We conducted a single-institution single-arm phase II trial hippocampal-sparing whole irradiation simultaneous integrated boost (HSIB-WBRT) to metastatic deposits in adult patients metastasis. Radiation...
Total body irradiation is an important part of the conditioning regimens frequently used to prepare patients for allogeneic hematopoietic stem cell transplantation (SCT). Volumetric-modulated arc therapy enabled total (VMAT-TBI), alternative conventional TBI (cTBI), a novel radiotherapy treatment technique that has been implemented and investigated in our institution. The purpose this study (1) report six-year clinical experience terms planning strategy delivery time (2) evaluate outcomes...
An indexed rotational immobilization system was developed for supine total body irradiation (TBI). Treatment plans had multi-isocentric volumetric modulated arc therapy (VMAT) beams to the upper and parallel-opposed fields lower body, with a 12 Gy prescription dose >90% of mean lung ∼8 Gy. In end-to-end test, point measurements <10% error. Compared conventional TBI, VMAT-based TBI technique increased by ∼1.0–1.5 decreased Overall treatment time ∼1.5 h, similar TBI.
<b><i>Background:</i></b> Skull base paragangliomas (SBP) are locally expansile tumors that can be treated with stereotactic radiotherapy favorable results. This report describes the results of 31 patients SBP CyberKnife delivering a total dose 25 Gray in five fractions. <b><i>Methods:</i></b> All five-fraction at single institution were identified between 2007 and 2013. Tumor volumetric analyses performed to assess responses radiotherapy....
Renal Cell Carcinoma (RCC) is a common malignancy world-wide that rising in incidence. Up to 10% of RCC patients present with inferior vena cava (IVC) tumor thrombus (IVC-TT). Although surgery the only treatment proven efficacy for IVC-TT, surgical management advanced (level III and IV) IVC-TT difficult high morbidity mortality, offers poor survival outcome. Currently, there are no options setting recurrent or unresectable IVC-TT. Even though may be resistant conventionally fractionated...
The objective of this study is to develop an automatic segmentation strategy for efficient and accurate metastatic brain tumor delineation on contrast-enhanced T1-weighted (T1c) magnetic resonance images (MRI) stereotactic radiosurgery (SRS) applications. proposed four-step metastases comprised pre-processing, initial contouring, contour evolution, triage. First, T1c are preprocessed remove the skull. Second, created using a multi-scaled adaptive threshold-based bounding box super-voxel...
The retroperitoneal margin is a common site of positive surgical margins in patients with resectable pancreatic cancer. Preoperative margin-intensive therapy (MIT) involves delivery single high dose ablative radiotherapy (30 Gy) focused on this surgically inaccessible margin, utilizing stereotactic techniques an effort to reduce local failure following surgery. In study, we investigated the motion regional organs at risk (OAR) 4DCT, evaluated dosimetric effects abdominal compression (AC)...
Radiosurgery is an established technique to treat cerebral arteriovenous malformations (AVMs). Obliteration of larger AVMs (> 10-15 cm3 or diameter > 3 cm) in a single session challenging with current radiosurgery platforms due toxicity. We present novel multistage stereotactic (SRS) for large intracranial (AVM) using the Gamma Knife system.Eighteen patients AVMs, which were previously treated staged SRS on Cyberknife platform, retrospectively selected this study. The contoured and divided...
Leukemia cutis, a form of extramedullary leukemia involving the skin, is poor prognostic marker and indicator imminent hematologic relapse chemotherapeutic resistance in patients. Although total skin electron beam radiotherapy commonly recommended for patients with its role effectiveness remains unclear. Here we describe 19-month-old infant acute myelogenous first diagnosed at 15 months age. It relapsed her 18 age, associated raised hyperpigmented lesions on chest scalp. Radiation treatment...
We aimed to evaluate changes in thyroid gland size during the treatment of malignancies outside head and neck with chemotherapy and/or external beam radiation. performed a retrospective review records adult patients treated at our institution radiation chest taxanes, alkylating agents, topoisomerase II inhibitor. Neck computed tomography (CT) images were used calculate volume before after therapy, using Vitrea® software or volumetric ellipsoid method. Thirty-seven included. After treatment,...