A5053960294- Advanced Radiotherapy Techniques
- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Lung Cancer Diagnosis and Treatment
- Breast Cancer Treatment Studies
- Management of metastatic bone disease
- Head and Neck Cancer Studies
- Global Cancer Incidence and Screening
- Medical Imaging Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Advances in Oncology and Radiotherapy
- Effects of Radiation Exposure
- Lung Cancer Treatments and Mutations
- Cancer Diagnosis and Treatment
- Mitochondrial Function and Pathology
- Cancer Risks and Factors
- Biotin and Related Studies
- Esophageal Cancer Research and Treatment
- Economic and Financial Impacts of Cancer
- Cancer survivorship and care
- Hepatocellular Carcinoma Treatment and Prognosis
- Spinal Fractures and Fixation Techniques
- Cancer-related Molecular Pathways
- Spine and Intervertebral Disc Pathology
- Cancer Treatment and Pharmacology
Michigan Healthcare Professionals
2019-2024
Radiation Oncology Institute
2019-2024
Northwestern University
2024
Mayo Clinic Hospital
2024
Huntsman Cancer Institute
2024
University of Utah
2024
University of California, San Diego
2024
Genesis HealthCare
2023
The Barbara Ann Karmanos Cancer Institute
2018-2022
21st Century Oncology (United States)
2019-2022
To evaluate the tolerability of escalating doses stereotactic body radiation therapy in treatment localized prostate cancer.Eligible patients included those with Gleason score 2 to 6 prostate-specific antigen (PSA) ≤ 20, 7 PSA 15, T2b, size 60 cm(3), and American Urological Association (AUA) 15. Pretreatment preparation required an enema placement a rectal balloon. Dose-limiting toxicity (DLT) was defined as grade 3 or worse GI/genitourinary (GU) by Common Terminology Criteria Adverse Events...
Importance Hypofractionated radiation therapy (RT) for prostate cancer has been associated with greater acute grade 2 gastrointestinal (GI) toxic effects compared conventionally fractionated RT. Objective To evaluate whether a hyaluronic acid rectal spacer could (1) improve dosimetry and (2) affect or higher GI hypofractionated Design, Setting, Participants This randomized clinical trial was conducted from March 2020 to June 2021 among 12 centers within the US, Australia, Spain, 6-month...
Randomized trials have established the long-term safety and efficacy of hypofractionated whole-breast radiotherapy, but little is known about acute toxic effects experienced by patients treated with hypofractionation as compared conventional fractionation, particularly in real-world settings from patient's own perspective.To evaluate prospectively collected data on patient-reported outcomes a cohort varying radiation fractionation schemes practices collaborating Michigan Radiation Oncology...
<h3>Importance</h3> Understanding whether physicians accurately detect symptoms in patients with breast cancer is important because recognition of facilitates supportive care, and clinical trials often rely on physician assessments using Common Toxicity Criteria for Adverse Events (CTCAE). <h3>Objective</h3> To compare the patient-reported outcomes (PROs) who received radiotherapy from January 1, 2012, to March 31, 2020, physicians' CTCAE assess underrecognition symptoms. <h3>Design,...
The purpose of this study is to compare the cost-effectiveness two external beam radiation therapy techniques for treatment low- intermediate-risk prostate cancer: stereotactic body (SBRT) and intensity-modulated (IMRT).A Markov decision analysis model with probabilistic sensitivity was designed various disease states a 70-year-old patient organ-confined cancer evaluate options.The Monte Carlo simulation revealed that mean cost quality-adjusted life-years (QALYs) SBRT IMRT were $22,152 7.9...
DAB2IP (DOC-2/DAB2 interactive protein) is a member of the RAS-GTPase-activating protein family. It often downregulated in metastatic prostate cancer and has been reported as possible prognostic marker to predict risk aggressive cancer. In this study, we furnish several lines evidence indicating that human PC3 cells deficient (shDAB2IP) exhibit increased clonogenic survival response ionizing radiation (IR) compared with control expressing an endogenous level (shVector). Radioresistance was...
Purpose: Castration-sensitive prostate cancer (CSPC) is a complex and heterogeneous condition encompassing range of clinical presentations. As new approaches have expanded management options, clinicians are left with myriad questions controversies regarding the optimal individualized CSPC. Materials Methods: The US Prostate Cancer Conference (USPCC) multidisciplinary panel was assembled to address challenges management. first annual USPCC meeting included experts in urology, medical...
Background: Management strategies for metastatic castration-resistant prostate cancer (mCRPC) have rapidly shifted in recent years. As novel imaging and therapeutic approaches made their way to the clinic, providers are encountering increasingly challenging clinical scenarios, with limited guidance from current literature. Materials Methods: The US Prostate Cancer Conference (USPCC) is a multidisciplinary meeting of experts intended address many challenges management. At first annual USPCC...
The retroperitoneal margin is a common site of positive surgical margins in patients with resectable pancreatic cancer. Preoperative margin-intensive therapy (MIT) involves delivery single high dose ablative radiotherapy (30 Gy) focused on this surgically inaccessible margin, utilizing stereotactic techniques an effort to reduce local failure following surgery. In study, we investigated the motion regional organs at risk (OAR) 4DCT, evaluated dosimetric effects abdominal compression (AC)...