William T. Li

ORCID: 0000-0003-0202-4850
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About
Contact & Profiles
Research Areas
  • Orthopedic Infections and Treatments
  • Orthopaedic implants and arthroplasty
  • Total Knee Arthroplasty Outcomes
  • Bone fractures and treatments
  • Hip and Femur Fractures
  • Anesthesia and Pain Management
  • Opioid Use Disorder Treatment
  • MicroRNA in disease regulation
  • Inflammatory mediators and NSAID effects
  • Bacterial biofilms and quorum sensing
  • Spinal Fractures and Fixation Techniques
  • Gastrointestinal disorders and treatments
  • Vascular Tumors and Angiosarcomas
  • Nail Diseases and Treatments
  • Oral and Maxillofacial Pathology
  • Pediatric Hepatobiliary Diseases and Treatments
  • Cervical and Thoracic Myelopathy
  • Vascular Procedures and Complications
  • Orthopedic Surgery and Rehabilitation
  • Dental Anxiety and Anesthesia Techniques
  • Molecular Biology Techniques and Applications
  • Drug-Induced Adverse Reactions
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Infectious Diseases and Mycology
  • Radiology practices and education

University of Pittsburgh Medical Center
2021-2025

University of Pittsburgh
2023

Rothman Institute
2019-2021

Thomas Jefferson University
2018-2021

Rothman Orthopaedics
2019-2021

Thomas Jefferson University Hospital
2019-2020

Orthopedic Institute
2019

Philadelphia University
2019

ABSTRACT Biofilm‐associated implant‐related bone and joint infections are clinically important due to the extensive morbidity, cost of care socioeconomic burden that they cause. Research in field biofilms has expanded past two decades, however, there is still an immense knowledge gap related many clinical challenges these biofilm‐associated infections. This subject was assigned Biofilm Workgroup during second International Consensus Meeting on Musculoskeletal Infection held Philadelphia USA...

10.1002/jor.24229 article EN Journal of Orthopaedic Research® 2019-01-24

Background: Revision total joint arthroplasty (TJA) has a higher rate of periprosthetic infection (PJI) compared with primary TJA, possibly as the result increased allogeneic blood transfusion. Tranexamic acid (TXA) is gaining popularity in revision TJA to minimize loss and need for transfusion; however, its effect on PJI reduction yet be investigated. The hypothesis this study was that administration TXA during protective against subsequent PJI. Methods: A prospectively maintained...

10.2106/jbjs.19.00925 article EN Journal of Bone and Joint Surgery 2020-06-19

Soft tissue sarcomas (STS) are rare malignant tumors often associated with poor outcomes and high local recurrence rates. Current tools for intraoperative definitive margin assessment include frozen section permanent pathology, respectively. Indocyanine green dye (ICG) is a historically safe fluorophore that has demonstrated efficacy in the surgical management of both breast gastrointestinal cancers. The utility ICG sarcoma surgery primarily been studied pre-clinical mouse models warrants...

10.3390/cancers15030582 article EN Cancers 2023-01-18

Background: Concerns for missed diagnoses have led to increased ordering of diagnostic imaging. Patients with suspected musculoskeletal tumors may undergo nondiagnostic and unnecessary imaging studies before referral a oncologist. This can result in patients receiving excessive radiation exposures, accruing costs, delays treatment, an burden on healthcare systems. Purpose: The purposes this study were (1) internally rate the usefulness tests completed oncology undergoing evaluation using...

10.5435/jaaosglobal-d-25-00015 article EN cc-by-nc-nd JAAOS Global Research and Reviews 2025-03-24

Introduction: The purpose of our study is to directly compare the rates instability after revision total hip arthroplasty (THA) between a modular dual mobility (DM) and conventional polyethylene single-bearing surface. Methods: We retrospectively reviewed consecutive series patients who underwent THA from 2012 2016 at single institution with minimum 2 years follow-up. Rates re-revision, dislocation, complications, short-form (SF-12) scores were compared DM groups. To control for confounding...

10.5435/jaaos-d-19-00532 article EN Journal of the American Academy of Orthopaedic Surgeons 2019-12-04

Robotic-arm assisted total knee arthroplasty (rTKA) was developed to provide for increased accuracy of component placement compared with conventional manual TKA (mTKA). Whether or not rTKA is cost-effective in a bundled payment model has yet be addressed. The purpose this comparative study evaluate the short-term clinical outcomes and mTKA. We retrospectively reviewed series 4,086 consecutive primary performed by one five surgeons across six different hospitals at our institution from...

10.1055/s-0040-1718603 article EN The Journal of Knee Surgery 2020-10-27

Background: Small bowel cancers, specifically duodenal cancer, occur at very low rates but require aggressive surgical resection when diagnosed. An even rarer finding is the presence of intestinal malrotation. Case Presentation: We present unique case a patient with both cancer and partial malrotation undergoing pancreaticoduodenectomy. discuss challenges faced techniques used to successfully perform in this circumstance. Conclusion: Understanding review imaging crucial preparing for tumor condition.

10.1089/pancan.2018.0005 article EN Journal of Pancreatic Cancer 2018-06-01

<h3>ABSTRACT</h3> <h3>Background:</h3> Postoperative C5 palsy is a common complication following cervical decompression, occurring more frequently after posterior-based procedures. It has been theorized that this the result of nerve stretch resulting from spinal cord drift with these As such, it thought to be less anterior decompression and fusion (ACDF). However, no consensus reached on its true etiology. The purpose study assess rate ACDF determine whether any radiographic or demographic...

10.14444/8029 article EN The International Journal of Spine Surgery 2021-04-01

Abstract Twenty‐four dogs with OS underwent limb amputation. Serum, tumour, and normal bone were harvested at time of surgery. RNA was extracted gene expression performed using quantitative polymerase chain reaction (qPCR). Tissue blood copper concentrations also determined spectrophotometry. Compared to bone, tumour samples had significantly higher expressions antioxidant 1 chaperone (ATOX1, p = .0003). levels than that serum ( &lt; .010) .038). Similar our previous observations in mouse...

10.1111/vco.12903 article EN cc-by-nc-nd Veterinary and Comparative Oncology 2023-05-06

It is traditionally believed that presence of fungal infection in the nail or skin patients a risk factor for subsequent infection. The literature devoid any evidence to confirm refute this belief. This study examined possible relationship between superficial mycoses and periprosthetic joint (PJI) undergoing total arthroplasty (TJA).This single-centre, retrospective who underwent primary TJA 2000 2018. 55 with nail, at time were identified variable number matching up 1:5 ratio was performed...

10.1177/11207000211037316 article EN Hip International 2021-09-12
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