- Systemic Sclerosis and Related Diseases
- Advanced Radiotherapy Techniques
- Inflammatory Myopathies and Dermatomyositis
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Radiomics and Machine Learning in Medical Imaging
- Lung Cancer Diagnosis and Treatment
- Eosinophilic Disorders and Syndromes
- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Medical Imaging Techniques and Applications
- Management of metastatic bone disease
- Dermatologic Treatments and Research
- Ultrasound and Hyperthermia Applications
- Dermatological and Skeletal Disorders
- Physiological and biochemical adaptations
- Atomic and Subatomic Physics Research
- Head and Neck Cancer Studies
- Endometrial and Cervical Cancer Treatments
- thermodynamics and calorimetric analyses
- Tumors and Oncological Cases
- Heat Transfer and Boiling Studies
- Skin Diseases and Diabetes
- Heterotopic Ossification and Related Conditions
- Mast cells and histamine
- Ultrasound in Clinical Applications
Johns Hopkins University
2021-2023
Johns Hopkins Medicine
2022-2023
Stanford University
2009-2021
Stanford Medicine
1996-2021
Palo Alto University
2011-2020
Kaiser Permanente Santa Clara Medical Center
2020
University of California, Los Angeles
1993-2014
UCLA Medical Center
2013
California State University Los Angeles
2008-2009
Yeungnam University
2005
Despite widespread implementation of policies to address mistreatment, the proportion medical students who experience mistreatment during clinical training is significantly higher than report mistreatment. Understanding barriers reporting from students' perspectives needed before effective interventions can be implemented improve learning environment.We explored reasons for not perceived or abuse experienced clerkships at David Geffen School Medicine UCLA (DGSOM).This was a sequential...
Background Peripheral blood leucocyte telomere length (PBL-TL) is associated with outcomes in patients idiopathic pulmonary fibrosis. Whether PBL-TL progression of systemic sclerosis-associated interstitial lung disease (SSc-ILD) unknown. Methods A retrospective observational cohort study was performed using prospectively collected data from 213 SSc followed at the University California San Francisco (UCSF) Scleroderma Center. measured by quantitative PCR DNA isolated peripheral blood....
Interstitial lung disease (ILD) is a frequent complication of systemic sclerosis (SSc), and ILD screening, characterization, monitoring are important for therapeutic decision-making prognostication. Lung ultrasonography (US) potential alternative imaging modality detection. In this study, our objective was to develop test novel US examination technique interpretation criteria detecting SSc-ILD.Lung acquisition performed by collecting short movies at 14 positions. SSc-ILD detection focused on...
Objective To determine the clinical phenotype and outcomes of patients with idiopathic inflammatory myopathies (IIMs) myocarditis. Methods Using Johns Hopkins Myositis Center Research Registry, we identified 31 adult IIM—out a total 3082 confirmed or suspected muscle disease—with an encounter code myocarditis from 2004 to 2021. Of these, 14 IIM were adjudicated have Information about demographics, autoantibodies, was retrospectively collected analyzed. Results myocarditis, median age at...
Objective The objective of this study is to evaluate racial/ethnic differences in disease manifestations and survival a US cohort patients with systemic sclerosis ( SS c), focus on Asian patients. Methods A retrospective was conducted among Kaiser Permanente Northern California adults an incident c diagnosis by rheumatologist from 2007 2016, confirmed chart review fulfill 2013 American College Rheumatology ACR )/European League Against Rheumatism EULAR ) classification criteria....
Objective To investigate the ability of ultrasound (US) compared to radiographs detect calcinosis in hands/wrists patients with systemic sclerosis (SSc), and assess US markers pathologic perfusion. Methods Patients SSc were evaluated for by radiograph US. The presence or absence was recorded patient, hand, anatomic zone; sensitivity specificity detection versus determined. Bilateral vascular measurements ulnar artery occlusion (UAO) finger pulp blood flow (FPBF) obtained. For each...
A dysregulated immune response plays a critical role in systemic lupus erythematosus (SLE) pathogenesis. Environmental factors such as viruses, including coronavirus 2 (COVID-19), have been described to play SLE presentation and exacerbation. These viruses trigger host’s humoral cellular immunities typically essential elimination of the viral infection. We present case Hispanic male who developed new-onset nephritis class II after COVID-19
Antifreeze proteins (AFPs) noncolligatively depress the freezing point of a solution and produce difference between melting points termed thermal hysteresis (TH). While mechanism enhancement effect is not well understood, various low-molecular-mass solutes including neutral salts have been identified to enhance TH activities AFPs. Here, monovalent on salting out an AFP from beetle Dendroides canadensis (DAFP-1) ice was treated using simple classical theory, relationship activity salt...
In the SENSCIS trial in patients with systemic sclerosis-associated interstitial lung disease (SSc-ILD), nintedanib reduced rate of decline forced vital capacity (FVC) (mL/year) over 52 weeks by 44% comparison placebo, manageable adverse events most patients. We analyzed efficacy and safety Asian race. Patients SSc-ILD were randomized to receive or placebo. The outcomes versus non-Asian Of 288 each treatment group, 62 (21.5%) group 81 (28.1%) placebo Asian; 90.2% enrolled countries. FVC was...
The aim of this study was to determine if correlations exist between quantitative parameters from dynamic contrast-enhanced (DCE) and diffusion-weighted (DW) MRI with National Comprehensive Cancer Network (NCCN) risk group, Gleason score (GS), maximum tumour diameter (MTD), pre-treatment prostate-specific antigen (PSA), clinical T stage prostate volume in cancer.We retrospectively reviewed 3T multiparametric reports on biopsy-proven cancer patients performed during radiation treatment...
Periarterial sympathectomy and arterial bypass are microsurgical techniques which the literature suggests can provide improvement in digital pain ulceration patients with systemic sclerosis (SSc) who have persistent symptoms despite medication management. This review summarizes relevant anatomy, medical therapies, operative techniques, surgical outcomes complications associated management of vascular manifestations SSc hand. Multidisciplinary collaboration between dermatology, rheumatology,...