A5076453597- Renal Transplantation Outcomes and Treatments
- Organ Transplantation Techniques and Outcomes
- Organ Donation and Transplantation
- Transplantation: Methods and Outcomes
- Blood groups and transfusion
- Cardiac, Anesthesia and Surgical Outcomes
- Enhanced Recovery After Surgery
- Complement system in diseases
- Adipokines, Inflammation, and Metabolic Diseases
- Organ and Tissue Transplantation Research
- Adipose Tissue and Metabolism
- Vaccine Coverage and Hesitancy
- Xenotransplantation and immune response
- Pregnancy and Medication Impact
- Renal Diseases and Glomerulopathies
- Hemoglobinopathies and Related Disorders
- Peroxisome Proliferator-Activated Receptors
- Cardiac Valve Diseases and Treatments
- Cardiac and Coronary Surgery Techniques
- Reproductive Health and Technologies
Instituto de Medicina Integral Professor Fernando Figueira
2013-2024
Instituto de Tecnologia de Pernambuco
2015
Faculdade Pernambucana de Saúde
2013
Hôpital Saint-Louis
2008-2010
The clinical importance of preexisting HLA antibodies at the time transplantation, identified by contemporary techniques, is not well understood. We conducted an observational study analyzing association between donor-specific (HLA-DSA) and incidence acute antibody-mediated rejection (AMR) survival patients grafts among 402 consecutive deceased-donor kidney transplant recipients. detected HLA-DSA using Luminex single-antigen assays on peak reactive current sera. All had a negative...
This study analyzes the influence of preformed DSA, identified by HLA-specific ELISA assays, on graft survival and evaluates incidence antibody-mediated rejection (AMR) in patients with without pregraft desensitization. Kidney at 8 years was significantly worse DSA (n = 43) than those 194)(p 0.03). The AMR is 9-fold higher (p < 0.001) their non-DSA 0.005). prevalence for detected historic serum 32.3% nondesensitized 41.7% desensitized patients. risk more elevated strongly positive (score...
The authors present their experience with 160 patients who underwent coronary artery saphenous vein bypass revascularization without cardiopulmonary bypass. distal sutures were performed interruption of the flow any devices for perfusion artery: proximal made tangential clamping aorta.
Since the pioneering work of Patel and Terazaki, presence an anti-donor anti-body IgG isotype, as demonstrated by a lymphocytotoxic assay on T cells, has been contraindication to transplantation, due very high rate graft loss reported (>80% in first few weeks posttransplant). The advent more sensible specific techniques detection anti-HLA antibodies (such ELISA or Luminex techniques) questioned this dogma, with number reports showing that despite donor-specific antibody (DSA), could be done...
Recent studies have shown that angiotensin-converting enzyme 2 (ACE2)/angiotensin (Ang) -(1-7)/Mas axis activation is able to improve the metabolic profile, enhance glucose tolerance and insulin sensitivity, parameters, counteract deleterious effects of Ang II. The endogenous ACE on profile mice are poorly studied. In this study, 12 weeks old male were treated with activator (diminazene aceturate, DIZE, 1 mg/kg/day, gavage) or saline (control) for 30 days followed by tests, sensitivity blood...
Successful renal transplant and consequent good graft function depend on a surgical technique, an anesthetic that ensures the hemodynamic stability of receiver, appropriate conditions recipient. Several factors can interfere with perfusion compromise its viability. The objective this study was to evaluate perioperative associated delayed (DGF) in transplantation patients.This is historical cohort patients who underwent between 2011 2013. Three hundred ten transplants were analyzed. DGF...
Background. The discard of expanded criteria donor (ECD) kidneys is unacceptably high, considering the growing demand for transplantation. Using machine perfusion may reduce rate, increase number transplants, and mortality on waiting list. Methods. We developed a 5-y Markov model to simulate incorporating pulsatile into current government-funded healthcare system. compared universal use static cold storage all with selective ECD kidneys. Real-life data were used compose cohort...
Objetivo: A utilização de órgãos doadores com injúria renal aguda (DIRA) parece estar associada a bons resultados, porém é necessário comprovar essa eficiência. Métodos: Foram analisados retrospectivamente os transplantes renais realizados na UGT-IMIP entre 11/2007 12/2012. categorização da amostra foi realizada acordo o tipo doador em critério ótimo (DCO), expandido (DCE), DIRA e vivo (DV). comparados nos quatro grupos, sobrevida do enxerto (SE) aos três meses um ano, clearance CR (CLCR3m)...
Lefaucheur, C.1; Loupy, A.2; Hill, G. S.2; Andrade, J.3; Antoine, Charron, D.3; Suberbielle, C.3; Glotz, D.1 Author Information