A5033859720- DNA Repair Mechanisms
- Pediatric health and respiratory diseases
- Optical Coherence Tomography Applications
- Immune responses and vaccinations
- Retinal Diseases and Treatments
- Olfactory and Sensory Function Studies
- Respiratory viral infections research
- Viral gastroenteritis research and epidemiology
- Stress Responses and Cortisol
- CRISPR and Genetic Engineering
- Epigenetics and DNA Methylation
- Carcinogens and Genotoxicity Assessment
- Neuroendocrine regulation and behavior
- Glaucoma and retinal disorders
- Gut microbiota and health
- Plant Genetic and Mutation Studies
Medical University of Vienna
2009-2022
We present a multi-functional optical coherence tomography (OCT) imaging approach to study retinal changes in the very-low-density-lipoprotein-receptor (VLDLR) knockout mouse model with threefold contrast. In retinas of VLDLR mice spontaneous retinal-chorodoidal neovascularizations form, having an appearance similar choroidal and (CNV RNV) neovascular age-related macular degeneration (AMD) or angiomatous proliferation (RAP). For this longitudinal study, were imaged every 4 6 weeks starting...
Training of the innate immune system with orally ingested bacterial extracts was demonstrated to have beneficial effects on infection clearance and disease outcome. The aim our study identify cellular molecular processes responsible for these immunological benefits. We used a murine coronavirus (MCoV) A59 mouse model treated activating extract Broncho-Vaxom (BV) OM-85. Tissue samples were analysed qPCR, RNA sequencing, histology, flow cytometry. After BV OM-85 treatment, interstitial...
Hygiene management protocols in laboratory mouse husbandries worldwide most commonly employ soiled bedding-exposed sentinel mice to monitor the occurrence of infections colonies. Using this approach, repeatedly receive a mixture used bedding, supplied by variety cages defined hygienic unit for period several months. Hereby, microorganisms shed bedding can infect animals and be detected subsequent health monitoring procedures. However, murine excrements carry more than only microorganisms....