Maria Deza Leon

ORCID: 0000-0003-0245-2177
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About
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Research Areas
  • Kawasaki Disease and Coronary Complications
  • HIV/AIDS Research and Interventions
  • Respiratory viral infections research
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Inflammasome and immune disorders
  • Viral Infections and Outbreaks Research
  • Time Series Analysis and Forecasting
  • HIV/AIDS oral health manifestations
  • Blood Coagulation and Thrombosis Mechanisms
  • Tracheal and airway disorders
  • Venous Thromboembolism Diagnosis and Management
  • Autoimmune and Inflammatory Disorders Research
  • HIV Research and Treatment
  • Medication Adherence and Compliance
  • Diabetes Management and Research
  • COVID-19 Impact on Reproduction
  • T-cell and B-cell Immunology
  • Delphi Technique in Research
  • Long-Term Effects of COVID-19
  • HIV-related health complications and treatments
  • COVID-19 Clinical Research Studies
  • Pneumonia and Respiratory Infections
  • Parvovirus B19 Infection Studies
  • HIV, Drug Use, Sexual Risk
  • Asthma and respiratory diseases

Children's Mercy Hospital
2025

Cincinnati Children's Hospital Medical Center
2023-2024

Children's Hospital of Michigan
2020-2021

Universidad Peruana Cayetano Heredia
2019

Johns Hopkins Medicine
2016

Johns Hopkins University
2016

Universidad de Costa Rica
2006

National Institutes of Health
1986

National Institute of Neurological Disorders and Stroke
1982

This study was conducted to assess the clinical spectrum, management, and outcome of SARS-CoV-2-related multisystem inflammatory syndrome in children (MIS-C). We reviewed medical records with MIS-C diagnosis seen at Children's Hospital Michigan Detroit between April June 2020. Thirty-three were identified including 22 who required critical care (group 1) 11 less intense inflammation 2). Children group 1 older (median 7.0 years) than those 2 2.0 years). Abdominal pain present 68% patients 1....

10.1007/s00431-021-03935-1 article EN other-oa European Journal of Pediatrics 2021-01-16

Abstract Background Acute bronchiolitis due to respiratory syncytial virus (RSV) is the leading cause of hospitalizations in infants United States. Most available data on RSV epidemiology were obtained from hospital cohorts or medically attended illnesses, focusing symptomatic children. We examined PREVAIL Cohort (2017–2020) healthy, term Cincinnati, Ohio understand infections a birth cohort under weekly surveillance. Table 1 Medical attendance by age group, Cohort, Ohio, 2017–2020 Methods...

10.1093/ofid/ofae631.906 article EN cc-by Open Forum Infectious Diseases 2025-01-29

A cross-sectional study was performed among seropositive individuals who sought HIV treatment at an outpatient clinic in San Jose, Costa Rica, to determine the prevalence, predictors, and reasons for nonadherence antiretroviral. structured, face-to-face interview administered 88 patients. The primary outcome of adherence measured as taking 100% medications within 3 days prior interview. number risk factors, including demographic information, knowledge, logistics regimen, management skills...

10.1089/108729104323076034 article EN AIDS Patient Care and STDs 2004-05-01

Devastating epizootics of simian hemorrhagic fever (SHF) have been iatrogenically initiated in captive colonies macaque monkeys by strains SHF virus emanating from asymptomatic persistently infected patas monkeys. We found that can be cleared their infection superinfection with which cause acute infections this species. All 20 animals subjected to procedure within 3 months. These were shown free the most sensitive vitro and vivo tests currently available periodic serum these over several...

10.3181/00379727-181-42244 article EN Experimental Biology and Medicine 1986-02-01

Abstract The objective of this study was to determine the serotype distribution and antibiotic resistance invasive pneumococcal disease (IPD) strains in children from Lima, Peru, before after introduction 7-valent conjugate vaccine (PCV7), which introduced national immunisation program on 2009. We conducted a prospective, multicentre, passive surveillance IPD during 2006–2008 2009–2011, right PCV7 Peru. performed 11 hospitals five private laboratories patients <18 years old, with sterile...

10.1017/s0950268819000037 article EN cc-by Epidemiology and Infection 2019-01-01

In this study, eight common polymorphisms associated with venous thrombosis (VT) and thrombophilia factors were analyzed in a Costa Rican case-control study. With the use of polymerase chain reaction (PCR) methods detected 120 patients 133 controls (mean age <40 years old). It was concluded that high level fibrinogen, antiphospholipid antibodies, family history, genotype 34LeuLeu FXIII OR 0.42 (0.20-0.89) showed significant effect on risk VT. Associations between VT genetic have been...

10.1002/cbf.1389 article EN Cell Biochemistry and Function 2006-12-29

Hemophagocytic lymphohistiocytosis (HLH) is a syndrome of excessive and maladaptive inflammation. In this review, we discuss how the clinical laboratory features HLH overlap with infection propose diagnostic treatment strategy to identify patients infections mimicking HLH.

10.1093/jpids/piae007 article EN Journal of the Pediatric Infectious Diseases Society 2024-01-22

Oligoclonal IgG bands were demonstrated in the cerebrospinal fluid of guinea pigs with experimental allergic encephalitis before clinical signs developed. No found serum these animals nor CSF or control animals. Immunofixation techniques that immunoglobulins γ G class.

10.3181/00379727-171-41510 article EN Experimental Biology and Medicine 1982-12-01

Abstract Background Respiratory syncytial virus (RSV) infections are common in children, resulting thousands of hospitalizations each year. Viral coinfections frequently detected during RSV infection, but the effect these is poorly understood, and most studies only include hospitalized children. We examined identified co-infection, rhinovirus/enterovirus (RE), on symptoms status medical care use a birth cohort healthy children with RSV. Methods PREVAIL CDC-funded, 2-year (2017–2020)...

10.1093/ofid/ofad500.2235 article EN cc-by Open Forum Infectious Diseases 2023-11-27

Asthma is popular with substantial patient morbidity and costs for healthcare.We performed a systematic literature review to identify different algorithms used in asthma diagnostic systems.In this paper we reviewed the 35 papers based on diagonosis system identified that these gives how much accuracy.We read prediction models designed help diagnostics determine clinicians evaluate patients asthma-suggesting symptoms primary care or similar settings I.INTRODUCTION nowadays commonly occurring...

10.22214/ijraset.2021.33029 article EN International Journal for Research in Applied Science and Engineering Technology 2021-02-20
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