A5008612551- Chronic Obstructive Pulmonary Disease (COPD) Research
- Asthma and respiratory diseases
- Air Quality and Health Impacts
- Energy and Environment Impacts
- Delphi Technique in Research
- School Health and Nursing Education
- Health disparities and outcomes
- Obesity, Physical Activity, Diet
- Mental Health Treatment and Access
- Vitamin D Research Studies
- Public Health and Nutrition
- COVID-19 impact on air quality
- Energy, Environment, and Transportation Policies
- Global Public Health Policies and Epidemiology
- Climate Change and Health Impacts
- Respiratory Support and Mechanisms
- Food Security and Health in Diverse Populations
- Child Nutrition and Water Access
- Inhalation and Respiratory Drug Delivery
- Health and Lifestyle Studies
- Global Maternal and Child Health
- Human Health and Disease
- Nutrition and Health in Aging
- Child Nutrition and Feeding Issues
- Health, psychology, and well-being
Johns Hopkins University
2016-2025
Leicestershire Partnership NHS Trust
2025
Johns Hopkins Medicine
2014-2024
Center for Non-Communicable Diseases
2023
National Institutes of Health
2022
University of Miami
2021
GTx (United States)
2020
Universidad de San Martín de Porres
2020
Universidad Científica del Sur
2020
University College London
2020
<h3>Importance</h3> Most of the global morbidity and mortality in chronic obstructive pulmonary disease (COPD) occurs low- middle-income countries (LMICs), with significant economic effects. <h3>Objective</h3> To assess discriminative accuracy 3 instruments using questionnaires peak expiratory flow (PEF) to screen for COPD LMIC settings. <h3>Design, Setting, Participants</h3> A cross-sectional analysis accuracy, conducted between January 2018 March 2020 semiurban Bhaktapur, Nepal; urban...
Chronic obstructive pulmonary disease (COPD) is a prevalent and burdensome condition in low- middle-income countries (LMICs). Challenges to better care include more effective diagnosis access affordable interventions. There are no previous reports describing therapeutic needs of populations with COPD LMICs who were identified through screening.
<h3>Background</h3> Biomass fuels are used for cooking in the majority of rural households worldwide. While their use is associated with an increased risk lung diseases and all-cause mortality, effects on cardiovascular disease (CVD) not well characterised. Exposure to biomass fuel smoke has been lung-mediated inflammation oxidative stress, which may increase atherosclerosis as evaluated by carotid intima-media thickness (CIMT), atherosclerotic plaque prevalence blood pressure....
Burning biomass fuels indoors for cooking is associated with high concentrations of particulate matter (PM) and carbon monoxide (CO). More efficient biomass-burning stoves chimneys ventilation have been proposed as solutions to reduce indoor pollution. We sought quantify PM CO exposures in urban rural households determine factors higher exposures. A secondary objective was identify chronic vs. acute changes cardiopulmonary biomarkers exposure smoke. conducted a census survey followed by...
Over 80% of rural households in Peru use solid fuels as their primary source domestic energy, which contributes to several health problems. In 2016, 6.7 million Peruvians were living areas. The Fondo de Inclusión Social Energético (FISE) LPG Promotion Program, began 2012 and is housed under the Ministry Energy Mining, a government-sponsored initiative aimed at reducing by increasing access clean fuel for cooking poor Peruvian households.We conducted mixed methods study incorporating data...
The relationship of body mass index (BMI) with lung function and COPD has been previously described in several high-income settings. However, few studies have examined this resource-limited settings where being underweight is more common. We evaluated the association between BMI outcomes across 14 diverse low- middle-income countries. included data from 12,396 participants aged 35–95 years used multivariable regressions to assess either while adjusting for known risk factors. An inflection...
More than 90% of the morbidity and mortality from chronic respiratory disease occurs in low-income middle-income countries (LMICs), with substantial economic impact. Preserved ratio impaired spirometry (PRISm) is a prevalent lung function abnormality associated increased high-income countries. We aimed to conduct post-hoc analysis cross-sectional study assess prevalence of, risk factors for, impact PRISm three diverse LMIC settings.
Background Pharmacological treatment of behavioral and psychological symptoms dementia is limited benefit. The addition non-pharmacological interventions often essential for optimal symptom control. Music a viable way to help patients communicate improve their quality life. Objective This study aims find the most effective use music in busy ward. Methods 17 inpatients (aged 63–93 years) with clinical diagnosis Alzheimer's disease took part over five weeks. lyrics presented via free-field...
Spirometry, while necessary for the diagnosis of COPD, remains a scarce and costly resource worldwide. Screening questionnaires may help to bridge diagnostic gap. We evaluated performance St. George's Respiratory Questionnaire (SGRQ) as screening tool using spirometry-confirmed COPD gold standard. screened adults aged ≥40 years in Bhaktapur, Nepal; Lima, Peru; Nakaseke, Uganda. Participants completed SGRQs pre-bronchodilator peak expiratory flow (PEF). defined post-bronchodilator FEV1/FVC...
Approximately 287,000 women die of causes related to pregnancy and childbirth every year. While effective interventions exist prevent maternal death, high quality impact evaluations for these are often lacking. We conducted a Delphi process consisting three rounds in which we asked health experts provide effectiveness estimates 31 intervention-cause death pairs relating mortality. Anonymous feedback the form medians histograms each question was given following first second rounds. A diverse...
Chronic obstructive pulmonary disease (COPD) is the end result of a susceptible individual being exposed to sufficiently deleterious environmental stimuli. More than 90% COPD-related deaths occur in low- and middle-income countries (LMICs). LMICs face unique challenges managing COPD; for example, deficient primary care systems present proper diagnosis management. Formal COPD requires quality-assured spirometry, which often limited urban health centres. Similarly, standard treatment options...
Introduction Sarcopenia and sarcopenic obesity (SO) have emerged as significant contributors to negative health outcomes in the past decade. We aimed estimate prevalence of probable sarcopenia, SO a community-dwelling population 1151 adults aged ≥55 years Lima, Peru. Methods This cross-sectional study was conducted between 2018 2020. defined presence low muscle strength (LMS) mass (LMM) according European (EWGSOP2), US (FNIH) Asian (AWGS2) guidelines. measured by maximum handgrip using...
Almost 90% of chronic obstructive pulmonary disease (COPD) deaths occur in low- and middle-income countries (LMICs), where there are large rural populations access to health care for COPD is poor. The purpose this study was compare urban-rural provider experiences regarding systemic facilitators barriers management treatment access.
Abstract Objectives To explore the experiences of older Peruvian adults living in urban areas Lima under lockdown due to National COVID-19 Emergency, this study analyzes how (aged 60 and older) exercise agency while also with negative impacts coronavirus disease 2019 (COVID-19) related control measures. Methods Between August December 2020, our research team conducted a telephone-based, qualitative study, which we undertook semistructured interviews purposive sample low-income chronic...
INTRODUCTION Serum 25-hydroxyvitamin D (25OHD) deficiency (&lt;50 nmol/l or 20ng/ml) has been associated with increased blood pressure (BP) in observational studies. A paucity of data on this relationship is available Latin American child populations. This study investigates the association between 25OHD levels and BP adolescents at risk for vitamin 2 Peruvian settings. METHODS In a population-based 1,441 aged 13–15 years, 1,074 (75%) provided serum sample analysis measurements....
Background Risk factors for COPD in high-income settings are well understood; however, less attention has been paid to contributors of low-income and middle-income countries (LMICs) such as pulmonary tuberculosis. We sought study the association between previous tuberculosis disease by using pooled population-based cross-sectional data 13 geographically diverse, low-resource settings. Methods six cohorts different LMIC settings, 6 3 continents relationship self-reported lung function...
Social relationships can impact youths' eating and physical activity behaviours; however, the best strategies for intervening in social environment are unknown. The objectives of present study were to provide in-depth information on roles that parents friends play related behaviours explore other behaviours.Convergent parallel mixed-methods design.Low-income, African American, food desert neighbourhoods Baltimore City, MD, USA.Data collected from 297 youths (53 % female, 91 mean age 12·3 (sd...
Introduction: The use of models and frameworks to design evaluate strategies improve delivery evidence-based interventions is a foundational element implementation science. To date, however, evaluative science such as Reach, Effectiveness, Adoption, Implementation, Maintenance (RE-AIM) have not been widely employed examine environmental health interventions. We take advantage unique opportunity utilize iteratively adapt the RE-AIM framework guide NIH-funded case studies clean cooking fuel...
Purpose The purpose of this study is to explore the influence social environment, including family and community relationships, on diabetes-related dietary change behaviors in a low-income, predominantly African American with limited access healthy foods. Methods Study methods included interviews focus groups adults diabetes members individuals low-income community. In analysis, interview participants 11 diabetes, one prediabetes, 8 or close friends diabetes. Information from 4 6 was groups....