A5079073968- Chronic Obstructive Pulmonary Disease (COPD) Research
- Delphi Technique in Research
- Asthma and respiratory diseases
- HIV/AIDS Research and Interventions
- HIV-related health complications and treatments
- Nursing Diagnosis and Documentation
- Inhalation and Respiratory Drug Delivery
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Public Health and Nutrition
- School Health and Nursing Education
- HIV/AIDS Impact and Responses
- Health Education and Validation
- Sleep and related disorders
- Primary Care and Health Outcomes
- Global Public Health Policies and Epidemiology
- Healthcare Systems and Reforms
- Mental Health Treatment and Access
- Global Health and Epidemiology
- Chronic Disease Management Strategies
- Respiratory Support and Mechanisms
- Pediatric health and respiratory diseases
- Pharmaceutical studies and practices
- Obstructive Sleep Apnea Research
- Neuroscience of respiration and sleep
- Health disparities and outcomes
Johns Hopkins University
2018-2025
Johns Hopkins Medicine
2019-2025
Center for Non-Communicable Diseases
2023
Kennedy Krieger Institute
2013
<h3>Importance</h3> Most of the global morbidity and mortality in chronic obstructive pulmonary disease (COPD) occurs low- middle-income countries (LMICs), with significant economic effects. <h3>Objective</h3> To assess discriminative accuracy 3 instruments using questionnaires peak expiratory flow (PEF) to screen for COPD LMIC settings. <h3>Design, Setting, Participants</h3> A cross-sectional analysis accuracy, conducted between January 2018 March 2020 semiurban Bhaktapur, Nepal; urban...
Chronic obstructive pulmonary disease (COPD) is a prevalent and burdensome condition in low- middle-income countries (LMICs). Challenges to better care include more effective diagnosis access affordable interventions. There are no previous reports describing therapeutic needs of populations with COPD LMICs who were identified through screening.
Abstract Adolescents and young adults with Down syndrome (DS) sometimes experience new‐onset mood disorder decline in adaptive skills. The clinical phenomenon is poorly characterized its pathogenesis not understood. possible contribution of obstructive sleep apnea (OSAS) to this has been studied. Subjects were ascertained as a convenience sample through our clinic for persons DS medical or mental health concerns between 2004 2009. When symptoms present an axis I diagnosis was made using...
More than 90% of the morbidity and mortality from chronic respiratory disease occurs in low-income middle-income countries (LMICs), with substantial economic impact. Preserved ratio impaired spirometry (PRISm) is a prevalent lung function abnormality associated increased high-income countries. We aimed to conduct post-hoc analysis cross-sectional study assess prevalence of, risk factors for, impact PRISm three diverse LMIC settings.
Spirometry, while necessary for the diagnosis of COPD, remains a scarce and costly resource worldwide. Screening questionnaires may help to bridge diagnostic gap. We evaluated performance St. George's Respiratory Questionnaire (SGRQ) as screening tool using spirometry-confirmed COPD gold standard. screened adults aged ≥40 years in Bhaktapur, Nepal; Lima, Peru; Nakaseke, Uganda. Participants completed SGRQs pre-bronchodilator peak expiratory flow (PEF). defined post-bronchodilator FEV1/FVC...
Chronic obstructive pulmonary disease (COPD) is the end result of a susceptible individual being exposed to sufficiently deleterious environmental stimuli. More than 90% COPD-related deaths occur in low- and middle-income countries (LMICs). LMICs face unique challenges managing COPD; for example, deficient primary care systems present proper diagnosis management. Formal COPD requires quality-assured spirometry, which often limited urban health centres. Similarly, standard treatment options...
Despite the rising burden of chronic respiratory disease globally, and although many medications are included in World Health Organization Essential Medications List (WHO-EML), there is limited information concerning availability affordability treatment drugs for conditions low- middle-income countries (LMICs).All public private pharmacies catchment areas Global Excellence COPD outcomes (GECo) study sites Bhaktapur, Nepal, Lima, Peru, Nakaseke, Uganda, were approached 2017-2019 to assess...
Chronic obstructive pulmonary disease (COPD) disproportionately affects low- and middle-income countries. Health systems are ill prepared to manage the increase in COPD cases.
Abstract Background The prevalence of hypertension is increasing among people living with HIV/AIDS (PLWHA) in low- and middle-income countries (LMICs). However, knowledge the complications management PLWHA Uganda remains low. We explored acceptability implementing (HTN) specific health education by community workers (CHWs) rural Uganda. Methods conducted a qualitative study consisting 22 in-depth interviews (14 PLWHA/HTN 8 CHWs), 3 focus group discussions (FGDs), 2 1 CHWs from Nakaseke...
Abstract Background Integrating evidence-based mental health services into primary care has been identified as one strategy for overcoming the treatment gap in low and middle-income countries, yet their uptake standard practice remains poor. The purpose of this study was to understand stakeholder perspectives regarding barriers facilitators integration settings Northern Iraq. Methods Using a convergent mixed methods design, quantitative qualitative questionnaires assessed respondent...
Rationale: The majority of the morbidity and mortality related to chronic obstructive pulmonary disease (COPD) occurs in low- middle-income countries (LMICs). Despite increasing burden COPD, disease-specific knowledge among healthcare workers patients LMICs remains limited. COPD questionnaires (COPD-KQ) are valid reliable tools assess can be employed settings with limited health literacy. Objectives: To develop validity reliability a COPD-KQ individuals three LMIC settings. Methods: Twelve...
More than 90% of chronic obstructive pulmonary disease (COPD)-related deaths occur in low- and middle-income countries; however, few studies have examined the illness experiences individuals living with providing treatment for COPD these settings. This study characterizes representations Nakaseke, Uganda from perspectives health care providers, village teams community members (CMs) COPD. We conducted 40 in-depth, semi-structured interviews (16 12 CMs, aged 25-80 years). Interviews were...
Abstract Background The prevalence of hypertension is increasing among people living with HIV/AIDS (PLWHA) in low- and middle-income countries (LMICs). However, knowledge the complications management PLWHA Uganda remains low. We explored acceptability implementing (HTN) specific health education by community workers (CHWs) rural Uganda. Methods conducted a qualitative study consisting 22 in-depth interviews (14 PLWHA/HTN 8 CHWs), 3 focus group discussions (FGDs), 2 1 CHWs from Nakaseke...
Background American Thoracic Society/European Respiratory Society guidelines recommend context-specific exposure assessments to diagnose interstitial lung disease (ILD). In sub-Saharan Africa, ILD diagnoses are rare, and locally validated questionnaires not used. Methods A physician-administered questionnaire was developed using a four-step mixed-methods modified Delphi approach. First, from high-income countries data Pneumotox were reviewed, compiled face-validated. Second, local pilot...