A5022586564- Algal biology and biofuel production
- Aquaculture Nutrition and Growth
- Seaweed-derived Bioactive Compounds
- Marine Bivalve and Aquaculture Studies
- Aquaculture disease management and microbiota
- Marine and coastal ecosystems
- Microbial Community Ecology and Physiology
- Microbial Natural Products and Biosynthesis
- Marine Sponges and Natural Products
- Marine and coastal plant biology
- Marine Biology and Ecology Research
- Aquatic Ecosystems and Phytoplankton Dynamics
- Metabolomics and Mass Spectrometry Studies
- Photosynthetic Processes and Mechanisms
- Physiological and biochemical adaptations
- Lipid metabolism and biosynthesis
- Invertebrate Immune Response Mechanisms
- Protein Hydrolysis and Bioactive Peptides
- Marine Toxins and Detection Methods
- Genomics and Phylogenetic Studies
- Shape Memory Alloy Transformations
- Marine Biology and Environmental Chemistry
- Environmental Toxicology and Ecotoxicology
- Tannin, Tannase and Anticancer Activities
- Microplastics and Plastic Pollution
Ningbo University
2016-2025
Zhejiang Ocean University
2019-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2024-2025
Zhejiang Marine Fisheries Research Institute
2024
Istituto Superiore per la Protezione e la Ricerca Ambientale
2023-2024
Fujian Normal University
2024
L'Oreal (United States)
2024
Shanxi Medical University
2024
Northwest University
2024
Yunnan University
2012-2024
Microalgae are considered to be natural producers of bioactive pigments, with the production pigments from microalgae being a sustainable and economical strategy that promises alleviate growing demand. Chlorophyll, as main pigment photosynthesis, has been widely studied, but its medicinal applications an antioxidant, antibacterial, antitumor reagent still poorly understood. Chlorophyll is most important in plants algae, which not only provides food for organisms throughout biosphere, also...
Dunaliella salina is an important source of natural β-carotene (containing 9-cis and all trans isomers) for industrial production. The phytohormone salicylic acid (SA) has been proven to have impacts on the stress resistance higher plants, but research microalgae currently unclear. In this study, effects SA growth, biochemical composition, antioxidant enzyme activity, key enzymes synthesis, cis-and trans-isomers in D. under different salt concentrations were investigated. results shown that...
Polyphenolic compounds in cranberries have been investigated to determine their role protection against cardiovascular disease and some cancers. Extracts of whole fruit were assayed for radical-scavenging activity tumor growth inhibition using seven cell lines. Selective K562 HT-29 cells was observed from a methanolic extract the range 16−125 μg/mL. Radical-scavenging greatest an composed primarily flavonol glycosides. Seven glycosides isolated purified further evaluation; anthocyanin...
Constitutive Wnt signalling is characterized by excessive levels of β-catenin protein and a frequent occurrence in cancer. APC Axin are key components the destruction complex that acts to promote degradation. The turn controlled tankyrases, members PARP-family poly-ADP-ribosylation enzymes. In colorectal cancer cells, which typically harbor mutations, inhibition tankyrase activity promotes stabilization attenuates signalling. Here, we examined effect inhibiting tankyrases breast cells with...
This study evaluated the possible prebiotic effects of dietary fucosylated chondroitin sulfate from Acaudina molpadioides (Am-CHS) on modulation gut microbiota and improvement in risk factors for chronic inflammation high fat diet-fed mice. The results showed that Am-CHS treatment greatly modified microbiota, including decrease Bacteroidetes, increase Firmicutes, elevation Lactobacillus (intestinal barrier protector) short chain fatty acid (SCFA)-producing bacteria (Lactobacillus,...
Fucoxanthin, a natural carotenoid abundant in edible brown seaweeds, has been shown to possess anti-cancer, anti-oxidant, anti-obesity and anti-diabetic effects. In this study, we report for the first time that fucoxanthin effectively protects against scopolamine-induced cognitive impairments mice. addition, significantly reversed increase of acetylcholinesterase (AChE) activity decreased both choline acetyltransferase brain-derived neurotrophic factor (BDNF) expression. Using an vitro AChE...
Phytohormones have attracted wide attention due to their important biological functions. However, detection is still a challenge because of complex composition, low abundance and diverse sources. In this study, novel method high-performance liquid chromatography with electrospray ionization tandem mass spectrometry was developed validated for the simultaneous determination ten phytohormones including indole-3-acetic acid, isopentenyladenine, isopentenyl adenosine, trans-zeatin riboside,...
Astaxanthin is a powerful antioxidant that possesses potent protective effects against various human diseases and physiological disorders. However, the mechanisms underlying its functions in cells are not fully understood. In present study, of astaxanthin on reactive oxygen species (ROS) production enzyme activity, as well mitogen-activated protein kinases (MAPKs), phosphatidylinositol 3-kinase (PI3K)/Akt, nuclear factor erythroid 2-related 2 (Nrf-2)/heme oxygenase-1 (HO-1) pathways...
The marine natural product fucoxanthin has been reported previously to produce anti-Alzheimer's disease (AD) neuroprotective effects in vitro and vivo. Fucoxanthin was also demonstrated be safe preclinical small population clinical studies, but the low bioavailability of central nervous system (CNS) limited its applications. To overcome this, poly lactic-
Yacon, Smallanthus sonchifolius (Poepp. & Endl.) H. Robinson, Asteraceae, an important economic species grown for its juicy tuberous root, is potentially beneficial in the diet to diabetics. The antioxidative activity of yacon root was studied by 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay. Antioxidants were extracted methanol and isolated purified gel permeation chromatography preparative reverse-phase HPLC. Two major antioxidants identified as chlorogenic acid tryptophan NMR mass...
Abstract Background Agaro-oligosaccharides derived from red seaweed polysaccharide have been reported to possess antioxidant activity. In order assess the live protective effects of agar-oligosaccharides, we did both in vitro and vivo studies based on own-made agaro-oligosaccharides, structural information this oligosaccharide was also determined. Method Structure agaro-oligosaccharides prepared with acid hydrolysis agar confirmed by matrix-assisted ultraviolet laser desorption ionization...