A5078955214- COVID-19 Clinical Research Studies
- Liver Disease Diagnosis and Treatment
- SARS-CoV-2 and COVID-19 Research
- Epilepsy research and treatment
- Cardiac Imaging and Diagnostics
- Respiratory Support and Mechanisms
- Intensive Care Unit Cognitive Disorders
- Hemodynamic Monitoring and Therapy
- Cardiac, Anesthesia and Surgical Outcomes
- Genetic Associations and Epidemiology
- Long-Term Effects of COVID-19
- Viral gastroenteritis research and epidemiology
- Immunodeficiency and Autoimmune Disorders
- Systemic Lupus Erythematosus Research
- Ultrasound in Clinical Applications
- Telomeres, Telomerase, and Senescence
- Neurological and metabolic disorders
- Sepsis Diagnosis and Treatment
- Gear and Bearing Dynamics Analysis
- interferon and immune responses
- Acute Myocardial Infarction Research
- Tribology and Lubrication Engineering
- Anesthesia and Sedative Agents
- COVID-19 and Mental Health
- Neuroscience and Neuropharmacology Research
Hospital Universitario del Tajo
2014-2025
Fundación Santa Fe de Bogotá
2022-2025
Tecnológico de Monterrey
2023-2025
Hospital Universitario Infanta Sofía
2025
Hospital Universitario del Henares
2025
Universidad Alfonso X el Sabio
2022-2025
Universidad de Los Andes
2022-2025
Instituto de Salud Carlos III
2009-2024
University of Quintana Roo
2022-2024
Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública
2024
MicroRNAs (miRNAs) have a crucial role in regulating immune response against infectious diseases, showing changes early disease onset and before the detection of pathogen. Thus, we aimed to analyze plasma miRNA profile at COVID-19 identify miRNAs as prognostic biomarkers severity survival.Plasma miRNome 96 patients that developed asymptomatic/mild, moderate severe was sequenced together with group healthy controls. Plasma immune-related were also assessed. showed 200 significant...
This study aimed to investigate the association of baseline coagulation proteins with hospitalization variables in COVID-19 patients admitted ICU, as well system changes after one-year post-discharge, taking into account gender-specific bias profile. We conducted a prospective longitudinal on 49 ICU-admitted patients. Proteins were measured using Luminex 200™. The between protein levels and was carried out by generalized linear models adjusted most relevant covariates. At ICU admission,...
Abstract Background Information is lacking regarding long-term survival and predictive factors for mortality in patients with acute hypoxemic respiratory failure due to coronavirus disease 2019 (COVID-19) undergoing invasive mechanical ventilation. We aimed estimate 180-day of COVID-19 requiring ventilation, develop a model mortality. Methods Retrospective, multicentre, national cohort study between March 8 April 30, 2020 16 intensive care units (ICU) Spain. Participants were consecutive...
Background metabolic changes through SARS-CoV-2 infection has been reported but not fully comprehended. This dysregulation affects multiple organs during COVID-19 and its early detection can be used as a prognosis marker of severity. Therefore, we aimed to characterize cytokine profile at onset relationship with disease severity identify profiles predicting progression. Material Methods performed retrospective cross-sectional study in 123 patients which were stratified asymptomatic/mild,...
We analyzed the association between HLA polymorphisms and susceptibility to SARS‐CoV‐2 infection disease severity. Genotyping data from a total of 9373 COVID‐19‐positive cases Spanish Coalition Unlock Research on Host Genetics COVID‐19 (SCOURGE) consortium 5943 population controls were included in study. found an alleles HLA‐B*14:02 HLA‐C*08:02 with lower risk ( p = 0.006, OR 0.84, 95% CI [0.75–0.95], 0.024, 0.86, [0.78–0.95], respectively). also HLA‐A*11:01 HLA‐C*04:01 associated severity...
In recent years, medical practice has followed two different paradigms: evidence-based medicine (EBM) and values-based (VBM). There is an urgent need to promote education that strengthens the relationship between these paradigms. This work designed establish foundations for a continuing (CME) program aimed at encouraging dialogue EBM VBM by determining values relevant everyday activities. A quasi-experimental, observational, comparative, prospective qualitative study was conducted analyzing...
Background/Objectives: The COVID-19 pandemic resulted in 675 million cases and 6.9 deaths by 2022. Despite substantial declines case fatalities following widespread vaccination campaigns, the threat of future coronavirus outbreaks remains a concern. Current treatments for have been repurposed from existing therapies other infectious non-infectious diseases. Emerging evidence suggests role genetic factors both susceptibility to SARS-CoV-2 infection response treatment. However, comprehensive...
Background: Acute myocardial infarction (AMI) with no evidence of relevant stenosis the coronary artery, known as (MI) nonobstructive arteries (MINOCA), has a prevalence up to 14%. The various causes MINOCA lead damage myocardium, and there are marked differences in diagnoses, prognoses, treatments. Although number patients affected is considerable owing high acute syndrome (ACS), have received little attention result that some may not receive appropriate treatment. Awareness this disease...
En este artículo se presentan los resultados de un estudio acerca del uso las Tecnologías la Información y Comunicación (TIC) por parte profesores Inglés en municipio sureste México. El forma proyecto nacional que pretende documentar analizar usos TIC maestros primarias públicas factores inciden dichos usos. La metodología es índole cuantitativa, con diseño tipo no experimental. el aquí reporta, empleó una muestra treinta profesores, seleccionados mediante muestreo probabilístico, a quienes...
Echocardiography is a non-invasive procedure which enables full assesment of cardiac function. The inferior vena cava (IVC) compliant blood vessel, easily distended, especially in cases hypovolemia. Assessment the physiologic characteristics IVC provides rapid distinction between low and high volume states offers clinician rapid, noninvasive way to guide resuscitation critically ill patients.
Reflex activation of seizures by thoughts or mental images is suggested patients but has not been objectively demonstrated. The authors present a report man with experiential complex partial reliably activated thinking about his family home. During monitoring, such were repeatedly induced in this way. Seizures refractory to antiepileptic drugs, ceased after left temporal resection. Pathologic examination showed cortical dysplasia.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes virus-induced-senescence. There is an association between shorter telomere length (TL) in disease 2019 (COVID-19) patients and hospitalization, severity, or even death. However, it remains unknown whether virus-induced-senescence reversible. We aim to evaluate the dynamics of TL COVID-19 1 year after recovery from intensive care units (ICU). Longitudinal study enrolling 49 admitted ICU due (August 2020 April 2021). Relative...
A shared genetic component between coronavirus disease 2019 (COVID-19) and idiopathic pulmonary fibrosis (IPF) has been described based on analyses of individual risk variants. Here we used a whole-genome polygenic score (PRS) approach to further evaluate age- sex-stratified overlap IPF severe COVID-19 give insight into biological mechanisms that might both inform therapeutic strategies for diseases. We results from the largest genome-wide association study clinically defined (4125 cases/20...
Introduction: The high polymorphism of the HLA system allows its typification to be used as valuable tool in establishing association various illnesses, immune and genetic profiles; it also provides a guide identifying compatibility among donors receptors organs transplants. Objective: To establish HLA-A, HLA-B, HLA.DRB1 allele, genotype haplotype frequencies patients treated at Clinica Colsanitas SA. Methods: 561 coming from different regions Colombia, who were attended 8 centers clinical...
Background: The link between coagulation system disorders and COVID-19 has not yet been fully elucidated. Aim: Evaluating the association of non-previously reported proteins with severity mortality. Design: Cross-sectional study 134 patients recruited at admission classified according to highest reached (asymptomatic/mild, moderate, or severe) 16 healthy control individuals. Methods: Coagulation levels (antithrombin, prothrombin, factor_XI, factor_XII, factor_XIII) CRP were measured in...