A5034418876- Muscle metabolism and nutrition
- Adipose Tissue and Metabolism
- Metabolism and Genetic Disorders
- Diet and metabolism studies
- Mitochondrial Function and Pathology
- Neuroscience and Neuropharmacology Research
- High Altitude and Hypoxia
- Cardiovascular and exercise physiology
- Nutrition and Health in Aging
- Neurological Disorders and Treatments
- Sulfur Compounds in Biology
- Biochemical effects in animals
- Cancer, Hypoxia, and Metabolism
- Gastrointestinal motility and disorders
- Heart Failure Treatment and Management
- Parkinson's Disease Mechanisms and Treatments
- Contact Dermatitis and Allergies
- Gastroesophageal reflux and treatments
- Traumatic Brain Injury and Neurovascular Disturbances
- Glycogen Storage Diseases and Myoclonus
- Cerebral Palsy and Movement Disorders
- Cardiac Ischemia and Reperfusion
- Pharmacological Effects and Assays
- Helicobacter pylori-related gastroenterology studies
- Alcoholism and Thiamine Deficiency
University of Pavia
2010-2020
Consorzio per Valutazioni Biologiche e Farmacologiche
2008
Istituto di Farmacologia Traslazionale
1989-2004
Fondazione Salvatore Maugeri
2000
Policlinico San Matteo Fondazione
1991-1996
Istituti di Ricovero e Cura a Carattere Scientifico
1991-1996
University of L'Aquila
1977-1979
Mediators released in the mucosal milieu have been suggested to be involved visceral hypersensitivity and abdominal pain patients with irritable bowel syndrome (IBS). However, their impact on myenteric neurons remains unsettled.Mucosal biopsies were obtained from descending colon of IBS controls. Mucosal mast cells identified immunohistochemically. The spontaneously mediators guinea pig electrically stimulated longitudinal muscle plexus (LMMP) preparations was assessed vitro by means...
Background: Growing evidence suggests that an altered microbiota composition contributes to the pathogenesis and clinical features in celiac disease (CD). We performed a comparative analysis of gut adulthood CD evaluate whether: (i) dysbiosis anticipates mucosal lesions, (ii) gluten-free diet restores eubiosis, (iii) refractory has peculiar microbial signature, (iv) salivary fecal communities overlap one. Methods: This is cross-sectional study where total 52 patients, including 13 active CD,...
Beta‐agonists and glucocorticoids are frequently coprescribed for chronic asthma treatment. In this study the effects of 4 week treatment with beta‐agonist clenbuterol (CL) glucocorticoid dexamethasone (DEX) on respiratory (diaphragm parasternal) limb (soleus tibialis) muscles mouse were studied. Myosin heavy chain (MHC) distribution, fibres cross sectional area (CSA), glycolytic (phosphofructokinase, PFK; lactate dehydrogenase, LDH) oxidative enzyme (citrate synthase, CS; cytochrome...
Abstract Introduction: The objective of this study was to investigate whether protein-calorie supplementation may enhance the cognitive retrieval patients with stroke. Patients and methods: A randomized, double-blind, controlled pilot clinical trial performed comparing diet plus regimens. subjects were 48 subacute stroke (≥ 14 days from index event). Anthropometric nutritional (3-day diary) variables, function (Mini-Mental State Examination; MMSE) determined before 21 after randomization in...
To better characterize the role of skeletal muscle in chronic heart failure we studied energetic charge, metabolites and enzyme activity energy production pathway. We selected 15 males with severe (NYHA class III, stable clinical conditions normal nutritional status) seven controls. Controls patients were submitted to biopsy vastus lateralis resting fasting conditions. Hormone profiles also evaluated. Our results showed near ATP, ADP AMP concentrations, but there substantially more...
Abstract The glutathione system (reduced and oxidized glutathione; redox index) was studied in the forebrain of male Wistar rats 5, 15, 25 months age following administration for 2 drinking water chemicals that induce oxidative stress: paraquat diethyldithiocarbamate (DDC) to increase superoxide radical formation, aminotriazole hydrogen peroxide hydroxyl generation, as well diamide ferrous chloride decrease cycle activity. Chronic oral phosphatidylcholine evaluated 25‐month‐old rats. Aging...
Introduction: The objective of this study was to investigate whether zinc (Zn2+) supplementation could contribute neurological retrieval patients suffering from strokes and low Zn2+ intake. Patients methods: Twenty-six with subacute stroke, having adequate daily energy (≥ 24 kcal/kg/day) protein 0.8 g/kg/day) intake (EPI) ingestion lower than two-thirds the recommended allowance 10 mg/day, were randomly allocated either a control group (n = 13) or where consisted mg Zn2+/day. Neurological...
Abstract Background Constipation is extremely common in patients with Parkinson's disease ( PD ) and has been described animal models. In this study, we investigated whether a ‐like degeneration of dopaminergic neurons the substantia nigra can influence peristalsis colonic segments rats by impacting on enteric transmission. Methods Male, Sprague–Dawley received unilateral injection neurotoxin 6‐hydroxydopamine (6‐ OHDA ), or saline, into medial‐forebrain‐bundle. Peristaltic activity was...