A5100322433- Liver Disease Diagnosis and Treatment
- Inflammatory Bowel Disease
- Microscopic Colitis
- Gastroesophageal reflux and treatments
- Thyroid Disorders and Treatments
- Diet, Metabolism, and Disease
- Nutrition and Health in Aging
- Neuroendocrine Tumor Research Advances
- Esophageal and GI Pathology
- Liver Disease and Transplantation
- Drug Transport and Resistance Mechanisms
- Colorectal Cancer Screening and Detection
- Eosinophilic Esophagitis
- Nutrition, Health and Food Behavior
- Anesthesia and Sedative Agents
- Airway Management and Intubation Techniques
- Autoimmune and Inflammatory Disorders
- Growth Hormone and Insulin-like Growth Factors
- Helicobacter pylori-related gastroenterology studies
- COVID-19 and healthcare impacts
- Education and Learning Interventions
- Pediatric Hepatobiliary Diseases and Treatments
- Healthcare Education and Workforce Issues
- Intensive Care Unit Cognitive Disorders
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Chungnam National University Hospital
2020-2025
Gyeongsang National University
2005-2023
Changwon National University
2023
National Cancer Center
2023
Ewha Womans University
2009-2023
Pediatrics and Genetics
2022
Inje University Busan Paik Hospital
2016-2021
Catholic University of Daegu
2021
Seoul Veterans Hospital
2019
Anyang University
2018
The risk of anti-tuberculosis (TB) drug-induced liver injury (DILI) in patients with chronic viral hepatitis (CVH) is not clear. aim this study was to investigate incidence and factors associated TB DILI CVH non-CVH patients. Retrospectively, a total 128 who received anti-TB medication from January 2005 February 2014 were reviewed. Among these, 83 had B virus (HBV), 41 C (HCV) 4 dual co-infected (HBV + HCV) 251 selected as the controls. There no human immunodeficiency Risk for analyzed using...
Background and Aims: Although paediatric Crohn's disease [CD] has a different phenotype clinical course to adult CD, its features surgical risks are poorly defined, especially in Asian countries.The aim of this study was investigate the long-term outcomes CD Korean population.Methods: We retrospectively analysed 594 patients who were younger than 18 years age at diagnosis between 1987 2013.Patient characteristics according Paris classification courses analysed.Results: The male-to-female...
Helicobacter pylori is a Gram-negative bacterium that associated with peptic ulcer disease (PUD) and gastric cancer. However, studies on the endoscopic finding factors related to H. Pylori infection in children are lacking. This study aimed evaluate prevalence dyspepsia. We retrospectively analyzed medical records of patients aged <18 years who underwent upper endoscopy for dyspepsia between January 2015 December 2022. was diagnosed using rapid urease test, dyspeptic symptoms included...
Background and Aim We analyzed the characteristics of gastrointestinal neuroendocrine tumors examined outcomes safety modalities in rectal tumors. Methods Between 2007 2011, a total 91 patients with were retrospectively reviewed terms Results Sixty‐six had underwent endoscopic mucosal resection ( EMR , n = 29), submucosal dissection ESD 23), or transanal microsurgery TEM 14). The complete rate was higher group (82.7%) (100%) compared to (65.5%) P < 0.046). complication (47.8%) than...
Small (≤ 2 cm) Hepatic Lesions in Colorectal Cancer Patients: Detection and Characterization on Mangafodipir Trisodium–Enhanced MRIKyoung Won Kim1, Ah Young Kim, Tae Kyoung Seong Ho Park, Hyun Jin Kyung Lee, Mi-Suk Kwon Ha, Pyo Nyun Cheon Kim Moon-Gyu LeeAudio Available | Share
Measurement of serum ceruloplasmin level is the first step in screening for Wilson's disease (WD). Despite rarity WD general population, levels are routinely measured through hepatitis both adults and children. Herein, we evaluated diagnostic value diagnosis among children with hepatitis.We retrospectively reviewed data on as a serologic marker patients at Asan Medical Center (Seoul, Korea) between from January 2004 to November 2013. The was confirmed by identification pathogenic variants...
Exclusive enteral nutrition (EEN) therapy effectively induces clinical remission in Crohn's disease (CD). It remains unclear, however, whether partial (PEN) can maintain remission. This study was performed to determine the abilities of oral EEN and PEN induce pediatric patients with CD, respectively.Pediatric CD who received at a single center 2000-2014 were identified retrospectively. Remission rates during 2 years period determined. Risk factors for failure identified.Of 66 started EEN, 61...
Metabolic liver disease (MLD) often progresses to life-threatening conditions. This study intends describe the outcomes of transplantation (LTx) for MLD at a living donor-dominant center where potentially heterozygous carrier grafts are employed.We retrospectively evaluated medical records 54 patients with who underwent LTx between November 1995 and February 2012 Asan Medical Center in Seoul, Korea. The cumulative graft patient survival rates were analyzed according age, or deceased donor...
The objective of this study was to determine health-related quality life (HRQoL) among chronic liver disease (CLD) subjects in South Korea using EuroQol five-dimension questionnaire (EQ-5D).The sample consisted 139 with CLD from the sixth Korean National Health and Nutrition Examination Survey (KNHNES VI). Data were analyzed SPSS program for descriptive statistics, t-test, ANOVA, Scheffe's test hierarchical multiple regression.Results indicated that marital status (P < 0.01), occupation...
Alagille syndrome (AGS) is a multisystem autosomal dominant disorder that affects the liver, heart, eyes, face, bone, and other organs. AGS caused by mutations in one of two genes, JAG1 or NOTCH2. We evaluated clinical features, outcomes, presence NOTCH2 Korean children with AGS.Between January 1997 December 2013, 19 were diagnosed at Asan Medical Center, Seoul, Korea. Their mutation status retrospectively analyzed.The prevalence features patients was as follows: dysmorphic facial 100% (n =...
Favourable clinical data were published on the efficacy of CT-P13, first biosimilar infliximab (IFX), in pediatric inflammatory bowel disease (IBD); however, few studies have compared effect endoscopic healing (EH) and drug retention rate between IFX originator CT-P13. Therefore, we aimed to compare EH Children with Crohn's (CD) ulcerative colitis (UC)/IBD-unclassified (IBD-U) at 22 medical centers enrolled, a retrospective review conducted 1-year last follow-up. Clinical remission,...
Obesity is risk factor for nonalcoholic fatty liver disease (NAFLD). However, nonobese patients are also increasingly susceptible to NAFLD. The aim of this study was compare the clinical characteristics obese and pediatric with NAFLD.We retrospectively studied 68 who were diagnosed NAFLD between January 2010 October 2016 at 10-18 years age. Body mass index ≥95th percentile age sex defined as obesity. Abdominal ultrasonography laboratory, anthropometrics measurements evaluated.Among 68, 26...
Sedative upper endoscopy is similar in pediatrics and adults, but it characteristically more likely to lead respiratory failure. Although recommended guidelines for pediatric procedural sedation are available within South Korea internationally, Korean endoscopists use different drugs, either alone or combination, practice. Efforts being made minimize the risk of while avoiding challenges. The purpose this study was collect analyze data on methods used by help physicians perform sedative...
: Although pediatric ulcerative colitis (UC) has a different phenotype and clinical course than adult UC, its features outcomes are poorly defined, especially in Asian populations. This study investigated the long-term of UC Korean population.We retrospectively analyzed 208 patients aged <18 years diagnosed with between 1987 2013. The patient characteristics at diagnosis according to Paris classification were analyzed.The male-to-female ratio was 1.3:1, median age 15.5 years. At diagnosis,...
Abstract Objectives Recently, several studies have reported the association between elevation of thyroid-stimulating hormone (TSH) levels and liver disease, especially, non‐alcoholic fatty disease (NAFLD). We aimed to evaluate incidence risk factors TSH in patients with disease. Methods retrospectively reviewed data aged <18 years who were diagnosed January 2015 March 2019. Results Among 77 patients, 17 (22.1%) had subclinical hypothyroidism 3 (17.6%) progressed overt hypothyroidism. A...
: Recently, the treatment of Crohn's disease (CD) has changed to a treat-to-target strategy, in which progression is prevented with early intervention. We analyzed long-term evolution nonstricturing, nonpenetrating (B1) at diagnosis and factors related pediatric CD.We retrospectively 402 patients between 2000 2013 who were younger than 18 years had B1 CD diagnosis. The median follow-up was 6.1 (range, 1 13 years). cumulative probabilities developing stricturing (B2) or penetrating (B3)...
It is uncertain whether non-alcoholic fatty liver disease (NAFLD) associated with subclinical hypothyroidism (SH) in pediatric patients. The purpose of this study was to investigated the prevalence and related factors SH patients NAFLD. We also evaluate association between fibrosis SH.We retrospectively reviewed medical records for aged 4 18 years who were diagnosed NAFLD tested thyroid function from January 2015 December 2019 at 10 hospitals Korea.The included 428 13.6%. In multivariate...
Background/Aims Crohn's disease (CD) is a chronic inflammatory bowel that presents with variable features and repeated aggravation. The incidence of CD increasing in Korea. We evaluated the clinical study population Busan Gyeongnam, Methods A hospital-based analysis included 619 patients diagnosed between March 1986 February 2013 from seven tertiary care hospitals Gyeongnam. Individual case records were reviewed regard to age at diagnosis, sex, location, behavior, medical surgical treatments...
We investigated whether the severity of anxiety among children undergoing endoscopy could affect sedation. prospectively recruited patients under 18 years age who were scheduled to undergo esophagogastroduodenoscopy (EGD). Baseline was evaluated using Spence Children's Anxiety Scale (SCAS). Our analysis considered type and dose sedative drugs, degree sedation, complications associated with sedation according scale score. The mean total SCAS T-scores each subscale score significantly higher...
Eating disorders often result in somatic complications, including cardiac abnormalities. Cardiac abnormalities may involve any part of the heart, conduction system, and can lead to sudden death. The current study aimed evaluate incidence complications pediatric patients with eating their associated factors.We retrospectively analyzed aged 10-18 years who were diagnosed DSM-V (Diagnostic Statistical Manual Mental Disorder-V) underwent electrocardiography (ECG) and/or echocardiography between...
Clinostomum complanatum is a laryngeal fluke whose hosts include birds and mammals.[1] In humans, infection occurs accidentally during the consumption of raw freshwater fish.[1,2].A 59-year-old female presented to our hospital with throat pain globus sensation. The patient had been prescribed Proton Pump Inibitor for 3 weeks at another hospital. continued medication, but discomfort persisted, she was admitted further examination. eaten fish 24 days before, symptoms occurred after eating...
Isolated hypogonadotropic hypogonadism (IHH) is known to decrease bone mineral density due deficiency of sex steroid hormone. Graves' disease also an important cause secondary osteoporosis. However, IHH does not preclude the development primary hyperthyroidism caused by disease, leading more severe osteoporosis rapidly. Here, we describe first case 35-year-old Asian female patient with accompanied and osteoporosis-induced multiple fractures. Endocrine laboratory findings revealed preserved...