A5064340553- Viral gastroenteritis research and epidemiology
- Inflammatory Bowel Disease
- Helicobacter pylori-related gastroenterology studies
- Congenital Anomalies and Fetal Surgery
- Microscopic Colitis
- Airway Management and Intubation Techniques
- Foreign Body Medical Cases
- Respiratory Support and Mechanisms
- Neonatal Respiratory Health Research
- Genetic factors in colorectal cancer
- Obesity, Physical Activity, Diet
- Eosinophilic Esophagitis
- Esophageal and GI Pathology
- Cholesterol and Lipid Metabolism
- Gastroesophageal reflux and treatments
- Bone Tumor Diagnosis and Treatments
- Tracheal and airway disorders
- Clinical Nutrition and Gastroenterology
- Heat shock proteins research
- Reconstructive Facial Surgery Techniques
- Clostridium difficile and Clostridium perfringens research
- Infant Development and Preterm Care
- Thermal Regulation in Medicine
- Gestational Trophoblastic Disease Studies
- Diet and metabolism studies
Chungbuk National University
2013-2024
Chungbuk National University Hospital
2017-2023
Seoul National University
2013-2023
National University College
2022
New Generation University College
2022
Weatherford College
2022
Samsung Medical Center
2007-2011
Sungkyunkwan University
2007-2011
Korea Institute of Drug Safety and Risk Management
2010
Pusan National University
2008
Foreign body (FB) ingestion in children is common and most are observed to be between 6 months 3 years of age. Although FBs the gastrointestinal tract pass spontaneously without complications, endoscopic or surgical removal may required a few children. Thus, FB presents significant clinical difficulty pediatric gastroenterological practice. Parameters that need considered regarding timing ingested children's age weight, presentation, time lapse since ingestion, last meal, type as well size...
The purpose of this study was to follow the natural course spontaneous passage (SP) ingested foreign bodies (FBs) in children.The medical records 249 patients who FBs were reviewed. In addition, they studied by telephone questionnaires up spontaneously passed FB. factors associated with SP such as age, type, size, and initial location analyzed.Foreign 145 (58.2%), endoscopic removal performed 100 (40.2%), operative 4 (1.6%). Most within 5 days. rates (SPRs) according following: 12.2% for...
The aim of this study was to evaluate the efficacy 'top-down' regimens for treatment paediatric Crohn's disease (CD) and compare it with effects 'step-up' treatment.We evaluated patients treated at 8 weeks after initiation treatment, 1 year follow-up. Of 29 who received infliximab, 11 cases refractory conventional therapy were categorized as group; 18 cases, moderate severe CD, group. Treatment assessed by Pediatric Disease Activity Index (PCDAI) scores.At weeks, remission achieved in three...
The Committee on Pediatric Obesity of the Korean Society Gastroenterology, Hepatology and Nutrition newly developed first Guideline Diagnosis Treatment in Children Adolescents to deliver an evidence-based systematic approach childhood obesity South Korea. following areas were systematically reviewed, especially basis all available references published Korea worldwide, new guidelines established each area with strength recommendations based levels evidence: (1) definition diagnosis overweight...
We aimed to investigate the disease phenotype of Korean pediatric Crohn's (CD) patients at diagnosis according Paris classification by comparison with from European multicenter 5-years recruitment children newly developed IBD (EUROKIDS registry).Korean and adolescents who had been diagnosed CD age <18 years during 2013-2016 were included in this retrospective study. Disease was classified classification, compared published data EUROKIDS study.A total 255 included. The median 14.7 (range,...
Background and AimsWe aimed to investigate the outcome in paediatric-onset Crohn's disease patients who had discontinued infliximab after maintaining clinical remission with combined immunosuppression, determine factors associated relapse.
Pneumatosis intestinalis (PI) in children is associated with immunosuppression, mucosal disruption from trauma, obstructive pulmonary disease, congenital heart and gastrointestinal infections. Our study the first report of norovirus infection-associated PI.A retrospective review was performed pediatric patients (older than 30 days) PI March 2005 to April 2009. Since December 2008, addition routine stool examinations, reverse-transcriptase polymerase chain reaction testing for calicivirus...
The purpose of this 24-week treatment study was to evaluate the effects three strategies after 8 weeks lansoprazole therapy for gastroesophageal reflux disease in children.Open-labelled, uncontrolled, prospective study.Samsung Medical Center, Seoul, Korea.37 erosive (ERD) and 20 non-erosive (NERD) patients were divided into groups by symptom assessment at weeks: (1) observation without 'symptoms-resolved' group, (2) 'on-demand' an additional 16 'symptoms-attenuated' group (3) continuous...
The clinical spectrum, histology, and endoscopic features of colonic polyps in the pediatric age group were studied to evaluate role colonoscopy children suspected having polyps.Seventy-six patients with colorectal studied. Investigations included barium enema (n=6), sigmoidoscopy (n=17), (n=53) at initial visit. Colonoscopy was also performed 23 who received or sigmoidoscopy. Data related age, gender, family history, signs, symptoms, size, location, polyp types, associated diseases...
In April 2020, a pediatric report of an unusual inflammatory illness associated with coronavirus disease 2019 (COVID-19) led to similar cases in Europe and North America, which was referred as multisystem syndrome children (MIS-C). Herein, we describe the case 12-year-old boy who had history polymerase chain reaction-confirmed COVID-19 developed MIS-C approximately three weeks after initial diagnosis COVID-19. High fever abdominal pain mimicking appendicitis manifestation MIS-C, could have...
The L-gulono-γ-lactone oxidase gene (Gulo) encodes an essential enzyme in the synthesis of ascorbic acid from glucose. On basis previous findings bone abnormalities Gulo (-/-) mice under conditions insufficiency, we investigated effect insufficiency on factors related to metabolism mice. Four groups were raised for 4 weeks differing namely, wild type; acid-sufficient mice, 3-week acid-insufficient and 4-week resulted significant weight loss Interestingly, average plasma osteocalcin levels...
Due to the broad spread, incidence, and genetic divergence of enteroviruses (EVs), it has been challenging deal with this virus that causes severe human diseases, including aseptic meningitis, myocarditis, encephalitis, poliomyelitis. Therefore, an efficient universal cloning system for reverse genetics highly divergent EVs contributes understanding viral pathology molecular mechanisms evolution.
Favourable clinical data were published on the efficacy of CT-P13, first biosimilar infliximab (IFX), in pediatric inflammatory bowel disease (IBD); however, few studies have compared effect endoscopic healing (EH) and drug retention rate between IFX originator CT-P13. Therefore, we aimed to compare EH Children with Crohn's (CD) ulcerative colitis (UC)/IBD-unclassified (IBD-U) at 22 medical centers enrolled, a retrospective review conducted 1-year last follow-up. Clinical remission,...
Abstract Respiratory distress is a common chief complaint in neonates admitted to the neonatal intensive care unit. Despite increasing use of non-invasive ventilation with respiratory difficulty, some them require advanced airway support. Delayed intubation associated increased morbidity, particularly urgent unplanned cases. Early and accurate prediction need for may provide more time preparation increase safety margins by avoiding late at high-risk infants. This study aimed predict within 3...
Heat shock proteins (HSPs) serve as molecular chaperones and play a role in cell protection from damage response to stress stimuli. The aim of this article is investigate whether HSP22 affects IL-8 expression vascular smooth muscle cells (VSMCs), which cellular factors are involved the HSP-mediated induction that type terms mitogen activated protein kinase (MAPK) transcription element. Exposure aortic (AoSMCs) not only enhanced release but also induced transcript via promoter activation. ERK...
Purpose: Crohn's disease (CD) can involve any site of the gastrointestinal tract (GIT).However, characteristics upper GIT involvement in CD are unclear, especially Eastern pediatric population.This study aimed to estimate prevalence and identify clinical features Korean children with CD.Methods: This was a retrospective multicenter cohort that included 52 patients who underwent esophagogastroduodenoscopy biopsy.The symptoms endoscopic histologic were identified according presence or absence...
A 10-day-old boy was transferred to our hospital due tachypnea. Patent ductus arteriosus (PDA), 4.8 mm in diameter, with small ASD diagnosed on echocardiography. Surgical ligation of the performed after failure three cycles ibuprofen. However, remained open routine postoperative echocardiography second day, and chest CT revealed inadvertent left pulmonary artery (LPA) rather than PDA. Emergent operation successfully reopened clipped LPA ligated same (second postoperative) day.<br...