Chang‐Ping Lin

ORCID: 0000-0003-0302-7711
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About
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Research Areas
  • Ocular Diseases and Behçet’s Syndrome
  • Corneal Surgery and Treatments
  • Corneal surgery and disorders
  • Glaucoma and retinal disorders
  • Retinal Diseases and Treatments
  • Intraocular Surgery and Lenses
  • Retinal and Macular Surgery
  • Ocular Infections and Treatments
  • Ocular Surface and Contact Lens
  • Retinal and Optic Conditions
  • Cytomegalovirus and herpesvirus research
  • Ophthalmology and Visual Impairment Studies
  • Retinal Imaging and Analysis
  • Systemic Lupus Erythematosus Research
  • Ocular Oncology and Treatments
  • CNS Lymphoma Diagnosis and Treatment
  • Vascular Malformations Diagnosis and Treatment
  • Lymphoma Diagnosis and Treatment
  • Hemoglobinopathies and Related Disorders
  • Parvovirus B19 Infection Studies
  • Retinal Development and Disorders
  • Blood groups and transfusion
  • Infectious Diseases and Tuberculosis
  • Connexins and lens biology
  • Herpesvirus Infections and Treatments

National Taiwan University Hospital
2012-2024

National Taiwan University
2004-2024

King's College London
2022

Changhua Christian Hospital
2008-2022

Cicely Saunders International
2022

Creative Commons
2022

Ophthalmology Associates (United States)
2019

Fujian Medical University
2008-2017

National Yang Ming Chiao Tung University
2014

First Affiliated Hospital of Shihezi University Medical College
2014

Background We examined Chinese health professionals' attitudes towards patients with AIDS vs hepatitis B. Methods A representative sample of 1101 professionals was used. Prejudicial and willingness to interact were measured based on two case vignettes. Results Statistical analyses revealed that had negative biases against acquired immunodeficiency syndrome (AIDS) reported much less than B patients. Perceived risk infection at work also negatively associated human virus (HIV)/AIDS, but...

10.1093/ije/dyl256 article EN International Journal of Epidemiology 2006-12-14

<h3>AIMS</h3> To report the special clinical manifestations and determine appropriate management of infectious scleral ulceration. <h3>METHODS</h3> A retrospective study was performed on 30 eyes with Information recorded patients' age, onset course disease, pathogenic organism, presentations, methods diagnosis, treatment, outcome. <h3>RESULTS</h3> 10 cases (33.3%) were accompanied by corneal involvement. Subconjunctival abscess noted in 16 (53.3%). 17 (56.7%) gave positive results pathogen...

10.1136/bjo.81.11.980 article EN British Journal of Ophthalmology 1997-11-01

Intracameral injection (ICI) of antibiotics and steroid is an effective method to deliver drugs into eyeballs, rapidly achieve therapeutic concentrations. The high intraocular concentrations, however, that occur by such injections can harm the corneal endothelium. MTT assay, [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide], has been used test cytotoxicity five (including amphotericin-B, colistin-M, sulbenicillin, amikacin, cephradine) a steroid, betamethasone, cultured porcine...

10.1089/jop.1996.12.35 article EN Journal of Ocular Pharmacology and Therapeutics 1996-01-01

Objective The incidence and prevalence of juvenile idiopathic arthritis (JIA) vary widely across the world but data in East Asia is lacking. Uveitis a serious cause morbidity JIA. This study aimed to analyze JIA, characteristics JIA-associated uveitis Taiwan. Methods A population-based cohort was conducted using Taiwan National Health Insurance Research Database. Each patient individually tracked from 1999 2009 identify diagnosis JIA International Classification Diseases diagnostic codes....

10.1371/journal.pone.0070625 article EN cc-by PLoS ONE 2013-08-05

Improper use of mitomycin-C in ocular medication may result damage to corneal cells. In this study, the toxic effects on cultured porcine keratocytes and endothelial cells were estimated by MTT, 3H-thymidine uptake cellular counting assay methods. It was found that caused a dose-dependent effect Both treated with at concentration ranging from 100, 10, 1, 0.1 0.01 μg/ml for 3 min, 5 min or 100 min. The 50% inhibitory dose (ID50) as measured MTT 0.40, 0.18, 0.16 mg/ml 0.27, 0.15, 0.14 mg/ml,...

10.1089/jop.1999.15.401 article EN Journal of Ocular Pharmacology and Therapeutics 1999-10-01

Cytomegalovirus (CMV) uveitis, a type of herpetic is major cause infectious uveitis. Anterior and posterior CMV uveitis have diverse clinical presentations treatment modalities. Based on expert consensus in Taiwan, this article provides suggestions regarding manifestations, diagnosis, strategies for based practice experience Taiwan. may distinct presentation. Polymerase chain reaction (PCR) an essential diagnostic tool to confirm diagnosis. Antiviral therapy the mainstay treatment. Different...

10.1016/j.jfma.2023.03.014 article EN cc-by-nc-nd Journal of the Formosan Medical Association 2023-03-30

To investigate changes in the vitreoretinal interface after anti-vascular endothelial growth factor (anti-VEGF) treatment highly myopic eyes.Eyes with choroidal neovascularization (mCNV) treated intravitreal injection of anti-VEGF a single-center were retrospectively reviewed. Fundus abnormalities and features optical computed tomography studied.A total 295 eyes from 254 patients recruited to study. Prevalence macular retinoschisis (MRS) was 25.4%, rates progression onset MRS 75.9% 16.2%,...

10.1007/s40123-023-00701-4 article EN cc-by-nc Ophthalmology and Therapy 2023-04-01

To evaluate the influence of fortified antibiotic eyedrops on corneal epithelial wound healing.We developed an in vitro wound-healing model to toxicity antibiotics. An excimer laser was used create defect 1.5 mm diameter, 70 microm depth central area porcine cornea. The intact animal globes were maintained incubator by a perfusion system. Fortified antibiotics: 10% piperacillin, 5% cefazolin, 0.5% chloramphenicol, vancomycin, 1% amikacin, 2% gentamicin, and 0.1% amphotericin B applied three...

10.1097/00003226-200003000-00014 article EN Cornea 2000-03-01

Abstract. We repon a new method combining the use of an amniotic membrane and cyanocrylate tissue adhesive to seal corneal perforation. A 47-year-old male suffered from alkali injury complicated with cornea! melting perforation in left eye. placed optimal size anterior chamber directly under lesion. The was then applied over site sealed successfully. Three weeks later, had dislodged. perforated lesion well adhered surrounding complete epithelial covering. Vision 20/25 six months after...

10.3928/1542-8877-20000301-15 article EN Ophthalmic surgery, lasers & imaging retina 2000-03-01

To determine the effect of pyrrolidine dithiocarbamate (PDTC), a nuclear factor (NF)-kappaB inhibitor, on chemokine and receptor expression thus elucidate role NF-kappaB in pathogenesis experimental autoimmune anterior uveitis (EAAU).Uveitis was induced Lewis rats with injection melanin-associated antigen into footpad. PDTC (200 mg/kg 100 mg/kg) administered intraperitoneally daily, beginning 1 day after immunization. The clinical inflammatory activity chamber recorded daily scored....

10.1167/iovs.04-0640 article EN Investigative Ophthalmology & Visual Science 2005-03-24

To present the immunologic status and clinical manifestations of patients who had infectious scleritis after pterygium excision.This prospective noncomparative study involved 18 eyes with (16 bacterial 2 fungal infections) a history excision from 1999 to 2001.The period between ranged 1 36 years. None any systemic autoimmune disease. Elevated erythrocyte sedimentation rates were found in 9 (50%) patients. serum C-reactive protein levels (75%) 12 Other serologic tests all negative. The most...

10.1097/01.ico.0000214228.44109.0f article EN Cornea 2006-07-01

We describe a modified method for scleral fixation of posterior chamber intraocular lenses (IOLs). A double-armed, 10-0 polypropylene (Prolene) suture on curved long needle is passed through groove in the sclera and retrieved within barrel bent 25-gauge opposite groove. Double transscleral passages enable 4-point provide better stability centration. Knots are buried completely In series 10 cases, IOLs were well centered, no sutures protruded from groove, vision all eyes improved. 1 case,...

10.1016/j.jcrs.2003.11.044 article EN Journal of Cataract & Refractive Surgery 2004-06-22

Purpose: To investigate the effects of mitomycin C (MMC) on rabbit cornea wound healing after photorefractive keratectomy (PRK). Materials and Methods: Rabbit corneas were stained with dichlorotriazinyl aminofluorescein immediately PRK. MMC was applied to right eye phosphate-buffered salt solution (PBS) left. Corneal epithelial rate corneal haze examined. Ultrasound pachymetry performed. Stromal collagen regeneration evaluated by fluorescent microscopy. We used terminal deoxyribonucleotidyl...

10.1089/108076804773710803 article EN Journal of Ocular Pharmacology and Therapeutics 2004-04-01

Purpose: This study aimed to evaluate treatment effects of intravitreal gas for macular hole with localized retinal detachment (RD) in highly myopic eyes and examine how the vitreomacular relationship other factors may influence outcomes. Methods: Twenty patients holes posterior RD, treated initially injection C3F8, were prospectively studied. Recurrent disease was repeated or vitrectomy according extent detachment. Length follow-up ≥ 12 months. Vitreomacular conditions determined before...

10.1111/j.1755-3768.2009.01649.x article EN Acta Ophthalmologica 2009-10-13

Corneal abrasion is the most common ocular complication associated with nonocular surgery, but toxic keratopathy rare.Three patients developed severe after orofacial surgery on left side general anesthesia. All underwent in right lateral tilt position protection reported irritation and redness their eyes operation. Alcohol-containing antiseptic solutions were used for presurgical preparation. Ophthalmic examination showed decreased visual acuity ranging from 20/100 to 20/400, corneal edema...

10.1001/jamaophthalmol.2016.0001 article EN JAMA Ophthalmology 2016-02-25
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