A5035024583- Scoliosis diagnosis and treatment
- Spinal Fractures and Fixation Techniques
- Cervical and Thoracic Myelopathy
- Spine and Intervertebral Disc Pathology
- Frailty in Older Adults
- Medical Imaging and Analysis
- Pelvic and Acetabular Injuries
- Cardiac, Anesthesia and Surgical Outcomes
- Hip and Femur Fractures
- Nutrition and Health in Aging
- Spinal Dysraphism and Malformations
- Aortic aneurysm repair treatments
- vaccines and immunoinformatics approaches
- T-cell and B-cell Immunology
- Colorectal Cancer Surgical Treatments
- Immunotherapy and Immune Responses
- Spinal Cord Injury Research
- Pregnancy-related medical research
- Coronary Interventions and Diagnostics
- Esophageal and GI Pathology
- Pelvic floor disorders treatments
- Minimally Invasive Surgical Techniques
- Bariatric Surgery and Outcomes
- Aortic Disease and Treatment Approaches
- Cardiac Imaging and Diagnostics
NYU Langone Health
2021-2024
New York University Langone Orthopedic Hospital
2021-2023
The Spine Institute
2021-2023
Neurological Surgery
2021-2023
Spinal Research
2022-2023
Tulane University
2020-2022
Orthopaedic Hospital
2022
New York Proton Center
2021
Financial Research (Hungary)
2021
Retrospective cohort study.This study aimed to evaluate the utility of modified frailty index (mFI-5) in a population patients undergoing spine surgery.The original (mFI-11) published as an American College Surgeons National Surgical Quality Improvement Program 11-factor was mFI-5 after variables were removed from recent renditions.Surgical isolated using current procedural terminology codes. mFI-11 (11) and (5) calculated 2005 2012. mFI determined by dividing factors present available...
Retrospective cohort study of a prospectively collected database.To compare clinical utility two common classification systems for adult spinal deformity (ASD) and determine whether both should be considered in surgical planning to improve patient outcomes.Surgical restoration appropriate Roussouly shape or SRS-Schwab ASD may outcomes.ASD patients with pre- 2-year postop (2Y) radiographic/health-related quality life (HRQL) data were grouped by "theoretical" "current" type. Univariate...
Study Design. Retrospective single-center study. Objective. To assess the influence of frailty on optimal outcome following ASD corrective surgery. Summary Background Data. Frailty is a determining factor in outcomes after surgery and may exert ceiling effect best possible outcome. Methods. patients with measures, baseline, 2-year ODI included. was classified as Not Frail (NF), (F) Severely (SF) based modified Index, then stratified into quartiles two-year improvement (most improved...
The impact of not achieving ideal realignment in the global alignment and proportion (GAP) score adult spinal deformity (ASD) correction on clinical outcomes is understudied at present.
Study Design. Retrospective review. Objective. The aim of this study was to evaluate outcomes matching Roussouly and improving in Schwab modifier following adult spinal deformity (ASD) surgery. Summary Background Data. Classification system sagittal shape the SRS-Schwab classification have become important indicators spine deformity. No previous studies examined both type modifiers postoperatively. Methods. Surgical ASD patients with available baseline (BL) 1 year (1Y) radiographic data were...
Retrospective review of a prospectively enrolled multicenter Adult Spinal Deformity (ASD) database.Investigate invasiveness and outcomes ASD surgery by frailty state.The Invasiveness Index incorporates deformity-specific components to assess correction magnitude. Intersections invasiveness, surgical outcomes, state are understudied.ASD patients with baseline 3-year (3Y) data were included. Logistic regression analyzed the relationship between increasing major complications or reoperations...
Given the physical and economic burden of complications in spine surgery, reducing prevalence perioperative adverse events is a primary concern both patients health care professionals. This study aims to identify specific factors predictive developing varying grades postoperative adult spinal deformity (ASD) patients, as assessed by Clavien-Dindo complication classification (Cc) system.Surgical ASD ≥18 years were identified American College Surgeons' National Surgical Quality Improvement...
Study Design. Retrospective cohort study of a prospective cervical deformity (CD) database. Objective. Identify factors associated with distal junctional kyphosis (DJK); assess differences across DJK types. Summary Background Data. may develop as compensation for mal-correction sagittal in the thoracic curve. There is limited understanding drivers, especially different Methods. Included: patients pre- and postoperative clinical/radiographic data. Excluded: previous fusion to L5 or below. was...
Antigen processing in the class II MHC pathway depends on conventional proteolytic enzymes, potentially acting antigens native-like conformational states. CD4+ epitope dominance arises from a competition among antigen folding, proteolysis, and MHCII binding. Protease-sensitive sites, linear antibody epitopes, T-cell epitopes were mapped plague vaccine candidate F1-V to evaluate various contributions dominance. Using X-ray crystal structures, likelihood (APL) predicts with significant...
Study Design. Retrospective review. Objective. Identify co-occurring perioperative complications and associated predictors in a population of patients undergoing surgery for adult spinal deformity (ASD). Summary Background Data. Few studies have investigated the development multiple, following ASD-corrective surgery. Preoperative risk stratification may benefit from identification factors with complications. Methods. Elective ASD National Surgical Quality Improvement Program (NSQIP) 2005 to...
Objective: To prioritize the cervical parameter targets for alignment.Methods: Included: deformity (CD) patients (C2–7 Cobb angle > 10°, lordosis sagittal vertical axis [cSVA] 4 cm, or chin-brow 25°) with full baseline (BL) and 1-year (1Y) radiographic parameters Neck Disability Index (NDI) scores; [C] cervicothoracic [CT] Primary Driver Ames type. Patients BL classified as low CD both of cSVA ( < cm) T1 slope minus (TS–CL) 15°) were excluded. assessed: meeting minimum clinically...
There is paucity on the effect of different cardiac diagnoses outcomes in elective spine fusion patients.Patients undergoing surgery were isolated PearlDiver database. Patients stratified by having a previous history coronary artery disease (CAD), congestive heart failure (CHF), valve disorder (valve), dysrhythmia, and no (control). Means comparison tests (chi-squared independent samples t-tests, as appropriate) compared differences demographics, diagnoses, comorbidities, procedural...
Study Design: This was a retrospective cohort study. Objective: The aim of this study to investigate associations between time surgical intervention and outcomes for central cord syndrome (CCS) patients. Background: As surgery is increasingly recommended patients with neurological deterioration CCS, it important the relationship outcomes. Materials Methods: CCS were isolated in Nationwide Inpatient Sample database 2005−2013. Patients grouped by surgery: same-day, 1-day delay, 2, 3, 4−7,...
The influence of frailty on economic burden following corrective surgery for the adult cervical deformity (CD) is understudied and may provide valuable insights preoperative planning.To assess baseline status CD surgery.Retrospective cohort.CD patients with scores two-year Neck Disability Index data were included. Frailty score was categorized by modified index into not frail (NF) (F). Analysis covariance used to estimate marginal means adjusting age, sex, surgical approach, sacral slope, T1...
Study Design. Retrospective cohort Objective. To assess whether patient outcomes and cost effectiveness of adult spinal deformity (ASD) surgery have improved over the past decade. Background. Surgery for ASD is an effective intervention, but one that also associated with large initial healthcare expenditures. Changes in profile last decade has not been evaluated previously. Methods. patients who received between 2008-19 were included. ANCOVA was used to marginal means outcome measures...
Retrospective review of a single-center spine database.Investigate the intersections chronological age and physiological via frailty to determine influence surgical invasiveness on patient outcomes.Frailty is well-established factor in preoperative risk stratification prediction postoperative outcomes. The profile operative patients with adult spinal deformity (ASD) who present as elderly not frail (NF) has yet be investigated. Our aim was examine outcomes ASD were NF elderly.Patients 18...
Malalignment of the cervical spine can result in cord compression, leading to a myelopathy diagnosis. Whether deformity or severity is stronger predictors surgical outcomes understudied.Surgical (CD) patients with baseline (BL) and up 1-year data were included. Modified Japanese Orthopaedic Association (mJOA) score categorized BL (mJOA = 18 excluded), moderate mJOA being 12 17 severe less than 12. was using mismatch between T1 slope lordosis (TS-CL), CL angle lower endplates C2 C7. Moderate...
More sophisticated surgical techniques for correcting adult spinal deformity (ASD) have increased operative times, adding to physiologic stress on patients and complication incidence. This study aims determine factors associated with time using a statistical learning algorithm.Retrospective review of prospective multicenter database containing 837 undergoing long fusions ASD. Conditional inference decision trees identified skin-to-skin cutoff points at which global effect. A conditional...
Identify the external applicability of American College Surgeons' National Surgical Quality Improvement Program (NSQIP) risk calculator in setting adult spinal deformity (ASD) and subsets patients based on frailty status.ASD were isolated our single-center database analyzed for shared predictive variables displayed NSQIP calculator. Patients stratified by (not frail <0.03, 0.3-0.5, severely >0.5), [T1 pelvic angle (TPA) > 30, incidence minus lumbar lordosis (PI-LL) 20], reoperation status....
Study Design. This was a retrospective review. Objective. To assess the factors contributing to durability of surgical results following adult spinal deformity (ASD) surgery. Summary Background. Factors long-term sustainability ASD correction are currently undefined. Materials and Methods. Operative patients with preoperatively (baseline) 3-year postoperatively radiographic/health-related quality life data were included. At 1 3 years postoperatively, favorable outcome defined as meeting at...
The lower instrumented vertebrae (LIVs) in cervical deformity (CD) constructs may have varying effects on patient outcomes that are still poorly understood.The objective of the study is to compare CD patients undergoing correction according relation LIV with primary driver (PD).Patients who met radiographic criteria for were included study. Patients stratified by PD deformity: (C) through AMES classification (TS-CL >20 or sagittal vertical axis >40) and thoracic (T) hyper/hypokyphosis (TK)...