Mirjam Thielen

ORCID: 0000-0003-0337-8570
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Research Areas
  • Cerebral Palsy and Movement Disorders
  • Botulinum Toxin and Related Neurological Disorders
  • Orthopedic Surgery and Rehabilitation
  • Nerve Injury and Rehabilitation
  • Stroke Rehabilitation and Recovery
  • Reconstructive Surgery and Microvascular Techniques
  • Shoulder Injury and Treatment
  • Muscle activation and electromyography studies
  • Shoulder and Clavicle Injuries
  • Nerve injury and regeneration
  • Transcranial Magnetic Stimulation Studies
  • Spinal Fractures and Fixation Techniques
  • Spine and Intervertebral Disc Pathology
  • Neurogenetic and Muscular Disorders Research
  • Peripheral Nerve Disorders
  • Scoliosis diagnosis and treatment
  • Burn Injury Management and Outcomes
  • Head and Neck Surgical Oncology
  • Dental Radiography and Imaging
  • Tracheal and airway disorders
  • Foot and Ankle Surgery
  • Organ and Tissue Transplantation Research
  • Cardiovascular Syncope and Autonomic Disorders
  • Nail Diseases and Treatments
  • Surgical Sutures and Adhesives

Klinikum Ludwigshafen
2021-2025

University Hospital Heidelberg
2018-2025

Heidelberg University
2018-2025

Orthopädische Universitätsklinik
2019

Peripheral nerve lesions are associated with debilitating long-term consequences. Albeit being essential for evidence-based clinical decision making, epidemiological and etiological data scarce. We therefore aimed to comprehensively analyze factors of peripheral in one the largest cohorts.We screened a total 110,667 patients treated at our level I trauma center between January 2012 July 2020 lesions. Subsequently, demographics, etiologies, concomitant injuries, lesion characteristics were...

10.3390/jpm12101673 article EN Journal of Personalized Medicine 2022-10-08

Abstract Background Peripheral nerve injuries are severe conditions with potential lifelong impairment, which is especially meaningful for the pediatric population. Knowledge on prevalence, injury mechanisms and concomitant is, therefore, of utmost importance to increase clinician awareness enable early diagnosis treatment. As current literature lesions scarce, we aimed analyze all details our patient Methods A total 110 667 patients treated at level 1 trauma center from 2012 2021 were...

10.1186/s40001-023-01082-x article EN cc-by European journal of medical research 2023-03-12

Aim To evaluate short‐term (1y postoperatively; E1) and long‐term (at least 4y E2) changes in hamstring muscle‐tendon length ( MTL ) lengthening velocity after children with bilateral cerebral palsy CP ). Method Three‐dimensional gait analysis was performed 19 (16 males, 3 females; 36 limbs; mean age at surgery 9y [ SD 3y]; range 6–10y) flexed knee gait, preoperative ankle dorsiflexion lower than 20 degrees, before (E0), E1 E2. Hamstring (normalized by leg length) were assessed via OpenSim...

10.1111/dmcn.14097 article EN Developmental Medicine & Child Neurology 2018-11-25

To evaluate the influence of supracondylar femoral derotation osteotomy (FDO) on hip abduction muscle force and frontal moments in children with bilateral cerebral palsy.For this retrospective cohort study 79 (36 females, 43 males; mean age at surgery 11y [SD 3y]; range 4-17y) palsy preoperatively 1-year postoperatively documented who received FDO 134 limbs were included. The control group consisted eight (two six 4y]; 5-17y) single-event multi-level without FDO.Hip joint impulse (p<0.001)...

10.1111/dmcn.14035 article EN Developmental Medicine & Child Neurology 2018-09-25

Abstract Background Injuries to the thenar muscle mass or branch of median nerve and resulting loss thumb opposition lead a massive impairment hand function. For decades, reconstructive approaches were based on tendon transfers. To broaden repertoire, we present free functional pronator quadratus flap as viable alternative for reconstruction provide specification its indication. We demonstrate our surgical technique single incision using flap. Based series three patients, which analyzed...

10.1186/s12893-021-01308-x article EN cc-by BMC Surgery 2021-07-12

Therapy-resistant neuroma pain is a devastating condition for patients and surgeons. Although various methods are described to surgically deal with neuromas, some discontinuity stump therapies have anatomical limitations. It widely known that neurotizable target axon ingrowth beneficial dealing neuromas. The nerve needs "something do". Furthermore, sufficient soft tissue coverage plays major role in therapy. We aimed, therefore, demonstrate our approach therapy of resistant neuromas...

10.3390/jpm13020313 article EN Journal of Personalized Medicine 2023-02-10

Zusammenfassung Hintergrund Schädigungen der Stammnerven oberen Extremität führen häufig zu anhaltenden, schwerwiegenden Einschränkungen in Funktion (Motorik) und Wahrnehmung (Sensibilität). Sowohl privat als auch beruflich können erhebliche auf physischer, psychischer sozioökonomischer Ebene persistieren. Indikationsstellung. Die frühe Indikationsstellung einem Nerventransfer kann die Reinnervationsstrecke verkürzen Einleitung motorischer oder sensorischer Axone das Zielorgan optimieren...

10.1055/a-2228-7062 article DE Handchirurgie · Mikrochirurgie · Plastische Chirurgie 2024-02-01

Popliteal pterygium syndrome (PPS) is a rare congenital disorder characterized by orofacial, cutaneous, musculoskeletal, and genital anomalies. Surgical interventions are necessary to address the severe knee flexion contracture equinovarus deformity, but there no established treatment guidelines.

10.3390/jpm14111097 article EN Journal of Personalized Medicine 2024-11-07

Complex regional pain syndrome (CRPS) can result in a devastating condition. For small number of patients, there is non-response to any existing multimodal therapies and they ultimately request amputation. Such drastic final decision not easy take for both the patient surgeon requires careful interdisciplinary assessments considerations. Furthermore, new surgical procedures, such as targeted muscle reinnervation (TMR) hybrid prosthetic fitting, multidisciplinary board advice should be...

10.3390/jpm12071169 article EN Journal of Personalized Medicine 2022-07-19

Objective The aim of the investigation was to assess contribution pain functional, social, and health-related quality-of-life outcomes in adults with cerebral palsy. Design This monocentric, prospective study included long-term data for ambulant palsy at levels I–III Gross Motor Function Classification System who had received orthopedic multilevel surgery adulthood whom preoperative postoperative three-dimensional gait analysis conducted, including Gait Profile Score. A questionnaire Visual...

10.1097/phm.0000000000001741 article EN American Journal of Physical Medicine & Rehabilitation 2021-02-27

Der Morbus Dupuytren ist eine gutartige, fibroproliferative Erkrankung, die Millionen Menschen weltweit betrifft. Typischerweise bilden sich zunächst Knötchen, gefolgt von festen Strängen an der palmaren Hand, zu fortschreitenden, irreversiblen Beugekontrakturen Finger führen. Dieser Beitrag fasst Epidemiologie, Risikofaktoren zur Entstehung des Dupuytren, Pathologie Erkrankung und verschiedene Therapieoptionen zusammen.

10.1055/a-1936-1291 article DE Orthopädie und Unfallchirurgie up2date 2023-03-28
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