A5003716661- Bladder and Urothelial Cancer Treatments
- Urinary and Genital Oncology Studies
- Urological Disorders and Treatments
- Prostate Cancer Diagnosis and Treatment
- Urinary Bladder and Prostate Research
- Pelvic floor disorders treatments
- Inflammatory Biomarkers in Disease Prognosis
- Prostate Cancer Treatment and Research
- Sexual function and dysfunction studies
- Infectious Disease Case Reports and Treatments
- Urologic and reproductive health conditions
- Esophageal Cancer Research and Treatment
- Urinary Tract Infections Management
- Genital Health and Disease
- Renal cell carcinoma treatment
- Epigenetics and DNA Methylation
- Health Systems, Economic Evaluations, Quality of Life
- Enhanced Recovery After Surgery
- Cancer, Lipids, and Metabolism
- Radiomics and Machine Learning in Medical Imaging
- Surgical Simulation and Training
- Ureteral procedures and complications
- Cardiac, Anesthesia and Surgical Outcomes
- Metabolomics and Mass Spectrometry Studies
- Spectroscopy Techniques in Biomedical and Chemical Research
Ludwig-Maximilians-Universität München
2016-2024
LMU Klinikum
2017-2024
München Klinik
2015-2022
Major urological guidelines do not currently recommend robot-assisted surgery compared with laparoscopic or open due to the lack of high-quality evidence. We aimed provide real-world data on evolution robotic urology and compare its perioperative outcomes those surgeries.
To determine whether transurethral en bloc submucosal hydrodissection of bladder tumours (TUEB) improves the quality resection compared to conventional tumour (TURBT) in patients with non-muscle-invasive cancer (NMIBC).A randomised, multicentre trial (HYBRIDBLUE) was conducted a superiority design. Six German academic centres participated between September 2012 and August 2015. Based on literature analysis, sample size for accurate histopathological assessment concerning muscle invasion...
Recent omics analyses of human biofluids provide opportunities to probe selected species biomolecules for disease diagnostics. Fourier-transform infrared (FTIR) spectroscopy investigates the full repertoire molecular within a sample at once. Here, we present multi-institutional study in which analysed fingerprints plasma and serum samples from 1639 individuals with different solid tumours carefully matched symptomatic non-symptomatic reference individuals. Focusing on breast, bladder,...
Abstract Background Salvage radical prostatectomy (sRP) is an important treatment option for patients with recurrent prostate cancer (PCa) after radiotherapy (RT) or focal therapy (FT). However, health-related quality of life (HRQOL) sRP depending on the primary understudied. Methods Patients who underwent RP PCa were analyzed. The outcome this study was HRQOL assessed by quality-of-life questionnaire (QLQ)-C30 and its specific QLQ-PR25 add-on. Secondary outcomes functional parameters...
Objective: The aim of the present study was to determine influence intraoperative and postoperative blood transfusion on cancer-specific outcome.Materials methods: Follow-up data were collected from 722 patients undergoing radical cystectomy for urothelial carcinoma bladder (UCB) between 2004 2014. Median follow-up 26 months (interquartile range 12–61 months). Outcome analyzed in relation amount different tumor stages. primary endpoint survival (CSS) after cystectomy. Kaplan–Meier analysis...
Abstract Introduction Radical cystectomy (RC) is the gold standard for muscle-invasive bladder cancer. Nevertheless, RC associated with substantial perioperative morbidity and mortality. We aimed to evaluate role of important risk factors in predicting long-term survival after RC. Methods An analysis prospective cohort patients undergoing open from 2004 2023 at our center was performed. Patients who died within one month were excluded study. A univariate multivariable Cox regression...
<b><i>Objectives:</i></b> Patients’ oncological outcome after radical cystectomy (RC) due to urothelial carcinoma of the urinary bladder (UCB) is always up for debate. There accumulating evidence on influence routine blood parameters. We aimed identify reasonable and easy-to-detect biomarkers, such as preoperative C-reactive protein (CRP) hemoglobin (Hb) levels, predictors overall survival (OS) cancer-specific (CSS) in patients undergoing RC UCB....
We objectively quantified daytime and nocturnal continence rates, defined predictive features for favorable outcomes after radical cystectomy orthotopic ileal neobladder creation.At 1 institution 1,012 cystectomies were performed between 2004 2015. Questionnaires evaluating the status sent to 244 patients. To objectify postoperative urine loss pad tests performed. Continence was as need up safety 10 gm or less per test. Predefined associative tested an influence on outcomes. Statistical...
Abstract We aimed to provide evidence on the trends and in-hospital outcomes of patients with low- high-flow priapism through largest study in field. used GeRmAn Nationwide inpatient Data (GRAND), provided by Research Center Federal Bureau Statistics (2008-2021), performed multiple patient-level analyses. included 6,588 men low-flow 729 priapism. Among priapism, 156 (2.4%) suffered from sickle cell disease, 1,477 (22.4%) required shunt surgery. Of them, only 37 (2.5%) received a concomitant...
Introduction of robot-assisted radical prostatectomy (RARP) has revolutionized the therapeutic landscape organ-confined prostate cancer (PCa). However, comparative analyses focused on health-related quality life (HRQOL) after RARP and open retropubic (ORP) are sparse. In current retrospective analysis,inclusion criteria encompassed PSA ≤ 10 ng/ml, pT2c, ISUP 3, age 65 years, preoperative continence. A propensity score-matched patient cohort [n = 418 (ORP: 209, RARP: 209)] was created HRQOL...
Abstract We aimed to assess the recommended annual hospital volume for inflatable penile prosthesis implantation (PPI) and provide evidence on perioperative outcomes of semi-rigid PPI in Germany. used GeRmAn Nationwide inpatient Data (GRAND) from 2005 2021 report largest study date with 7,222 patients. 6,818 (94.4%) patients underwent 404 (5.6%) PPI. Inflatable was significantly associated shorter length stay (difference 2.2 days, 95%CI: 1.6–2.7, p < 0.001), lower odds urinary tract...
<b><i>Purpose:</i></b> With a median age at diagnosis of 73 years, bladder cancer has the highest all cancers. Age alone seems to be an independent risk factor for developing disease with peak advancing into range 85 years. As demographic changes will lead ever more aging population in western countries, incidence advanced malignancies rise. We, therefore, analyzed contemporary radical cystectomy (RC) series single high-volume center on patients undergoing RC...
ObjectivesTo assess the impact of preoperative lower urinary tract symptoms (LUTS) on long-term health-related quality life (HRQOL) up to 10 years after radical prostatectomy (RP) for prostate cancer (PC).MethodsWithin our prospective institutional database 6487 patients treated with RP PC (2008– 2020), 2727 LUTS (IPSS score ≥8) were identified. A 1:1 propensity-score matched analysis 3056 men (n=1528 LUTS, n=1528 no LUTS) was conducted. Primary endpoint HRQOL (based EORTC QLQ-C30 and PR25)....
Purpose Profound endourological skills are required for optimal postoperative outcome parameters after transurethral resection of the prostate (TURP). We investigated Karl Storz (Tuttlingen, Germany) UroTrainer virtual simulation training TURP. Materials and Methods Twenty urologists underwent a reality (VR) TURP training. After needs analysis, performance scores self-rated surgical were compared before curriculum, realism simulator was assessed, level experience VR evaluated. Statistical...