A5002743696- Shoulder Injury and Treatment
- Elbow and Forearm Trauma Treatment
- Bone fractures and treatments
- Shoulder and Clavicle Injuries
- Orthopedic Surgery and Rehabilitation
- Bone Tumor Diagnosis and Treatments
- Orthopaedic implants and arthroplasty
- Hip disorders and treatments
- Anatomy and Medical Technology
- Osteoarthritis Treatment and Mechanisms
- Dupuytren's Contracture and Treatments
- Cancer Diagnosis and Treatment
- Sarcoma Diagnosis and Treatment
- Bone health and treatments
- Medical Imaging and Pathology Studies
- Total Knee Arthroplasty Outcomes
- Tendon Structure and Treatment
- Musculoskeletal synovial abnormalities and treatments
- Cerebral Palsy and Movement Disorders
- Surgical Simulation and Training
- Orthopedic Infections and Treatments
- Neurogenetic and Muscular Disorders Research
- Glycosylation and Glycoproteins Research
- Lower Extremity Biomechanics and Pathologies
- Biomedical and Engineering Education
Istituto Ortopedico Rizzoli
2012-2024
National and Kapodistrian University of Athens
2017
Sapienza University of Rome
2014
University of Padua
2014
Mayo Clinic in Arizona
2014
Kuopio University Hospital
2014
University of Sassari
2014
Orthopedic Institute
2008
Polyclinic Medical University
1995
Complex deformities of lower limbs are frequent in children with genetic or metabolic skeletal disorders. Early correction is frequently required, but it technically difficult and burdened by complications recurrence. Herein, we described the case a 7-year-old girl affected severe bilateral genu varum due to spondyloepiphyseal dysplasia. The patient was treated patient-specific osteotomies customized structural wedge allograft using Virtual Surgical Planning (VSP) 3D-printed instrumentation...
To evaluate the health-related quality of life and associated risk factors for Multiple Osteochondromas patients.
Multiple osteochondromas is a rare hereditary skeletal disorder, characterized by bony protrusions arising from growth plates on long bones during development. The disorder frequently leads to diminished stature, deformities and functional limitations. Understanding of the natural history multiple its evolution in children adolescents limited.To provide valuable information osteochondromas, inform recommendations for treatment prevent impairments caused osteochondromas.This retrospective...
Multiple osteochondromas (MO) is a rare disorder, characterized by benign osteocartilaginous tumors (osteochondromas), arising from the perichondrium of bones. The increase during growth, frequently causing deformities and limitations. Our study aims to analyze data captured Registry Osteochondromas, refine Istituto Ortopedico Rizzoli (IOR) Classification, providing representative picture phenotypic manifestations throughout lifespan. We conducted single-institution cross-sectional study....
Background: Neglected fractures of the lateral humeral condyle (LHC) are misdiagnosed or insufficiently treated fractures, presenting later than 3 weeks after injury. The management neglected LHC in children remains controversial. Methods: Twenty-seven were included this retrospective study. Charts and medical records investigated for demographics, time interval between injury treatment, type treatment. Baseline radiographs assessed fracture grading displacement. Final bone healing,...
Introduction The present study aims to describe a large cohort of Italian patients affected by osteogenesis imperfecta, providing picture the clinical bony and non-bony features molecular background improve knowledge disease inform appropriate management in practice. Methods A total 568 subjects (from 446 unrelated families) imperfecta who received outpatient care at Istituto Ortopedico Rizzoli from 2006 2021 were considered study. Results Skeletal extraskeletal analyzed showing lower height...
The purpose of this study is to evaluate the incidence and severity residual elbow instability in children treated for posterior (PED) or postero-lateral (PLED) dislocation. This retrospective included all younger than 14 years age with a confirmed diagnosis acute post-traumatic dislocation (ED). Subjective data such as perceived pain, stiffness impact daily activities, objective skin lesions, surgical-site infections, range motion were recorded. All patients underwent milking test, chair...
Treatment of cases congenital pseudarthrosis the fibula presenting with severe or progressive valgus deformity in early childhood is challenging. The purpose study presented was to analyse deforming mechanisms get therapeutic recommendations for this condition. A 2.5-year-old child treated by resection and distal tibiofibular fusion (Langenskiold operation) autogenous bone grafting, associated subtalar arthroereisis: correction achieved. 21-month-old pseudarthrosis, homologous grafting...
The induction and inhibition of human hepatic cytochrome P450 (CYP) isoforms by crystalline glucosamine sulfate (CGS) was investigated in vitro. Inhibition CYP1A2, CYP2E1, CYP2C19, CYP2C9, CYP2D6, CYP3A4 CGS assessed using recombinant enzymes incubated with (up to 3 mM expressed as free base). Induction CYP2B6, CYP2C19 (0.01, 0.3 mM) evaluated cryopreserved hepatocytes, determining CYP mRNA expression quantitative RT-PCR. produced no or any the tested at concentrations hundred folds higher...
Background: Multiple osteochondromas is a rare skeletal disorder characterized by the presence of osteocartilaginous protrusions causing bony deformities, especially around knee. Guided growth temporary hemiepiphyseal stapling treatment choice to correct deformity modulating residual physeal lower limbs. Although this procedure increasingly practiced, inconclusive evidence exists regarding its effectiveness in children with multiple osteochondromas. The study aims compare outcomes for...
The study of CAD (computer aided design) modeling, design and manufacturing techniques has undergone a rapid growth over the past decades. In medicine, this development mainly concerned dental maxillofacial sectors. Significant progress also been made in orthopedics with pre-operative simulations, printing bone models production patient-specific instruments. However, traditional procedure that formulates surgical plan based exclusively on two-dimensional images interventions performed...
Septic arthritis of the shoulder in children is a rare condition. The diagnosis may present some difficulties and, consequently, appropriate treatment often delayed. Main sequelae are humeral shortening, joint instability, premature and limited range motion. We report case septic child who was treated by means arthroscopy. A 6-year-old boy presented with history fever, pain functional impairment that were lasting despite having undergone antibiotic therapy for 28 days (amoxicillin per os,...