A5100356738- Sleep and related disorders
- Sleep and Work-Related Fatigue
- Stroke Rehabilitation and Recovery
- Gastric Cancer Management and Outcomes
- Gut microbiota and health
- COVID-19 and Mental Health
- Clostridium difficile and Clostridium perfringens research
- Ferroptosis and cancer prognosis
- Cancer, Lipids, and Metabolism
- Sleep and Wakefulness Research
- Lung Cancer Treatments and Mutations
- Infant Nutrition and Health
- Metastasis and carcinoma case studies
- Cancer Immunotherapy and Biomarkers
- Vestibular and auditory disorders
- Long-Term Effects of COVID-19
- Genetic factors in colorectal cancer
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Colorectal Cancer Treatments and Studies
- Acute Ischemic Stroke Management
- Gastrointestinal Tumor Research and Treatment
- Urologic and reproductive health conditions
- Inflammatory Biomarkers in Disease Prognosis
- Cancer Risks and Factors
- Prostate Cancer Diagnosis and Treatment
Fourth Hospital of Hebei Medical University
2025
Hebei Medical University
2025
Liaocheng University
2024
Nanjing Medical University
2017-2024
Tianjin Huanhu Hospital
2016-2024
Zhengzhou People's Hospital
2024
Inner Mongolia University of Science and Technology
2024
Jiangsu Cancer Hospital
2020-2024
Hunan University of Traditional Chinese Medicine
2024
Shihezi University
2024
Systemic immune-inflammation index (SII), calculated by immunoinflammatory cell counts of peripheral blood, is considered a predictor survival outcome in several solid tumors, including gastric cancer (GC). However, there no study focusing on the prognostic value SII early stage GC. This aims to compare prediction capabilities inflammatory indices, nutritional and tumor markers further verify superior I-II GC patients after surgery.In this study, 548 (358 training group 190 validation group)...
Hyperuricemia (HUA) is a potential risk factor for developing insulin resistance, hypertension, dyslipidemia and cardiovascular disease. Therefore, we studied the prevalence of HUA associated factors in population two provinces northern China. Based on research Chinese Physiological Constant Health Conditions conducted 2008–2010, enrolled 29,639 subjects randomized, stratified study four sampling areas Heilongjiang Province Inner Mongolia Autonomous Region. We collected 13,140 serum samples...
High-temperature weather appears in high frequency, big strength, and long duration the summer. It is therefore important to study effects of high-temperature on sleep quality appetite. Ten healthy college students were selected as subjects. The experiment conditions divided by daily maximum temperature into 28 °C, 32 36 38 °C. objective was measured an intelligent monitoring belt, subjective a questionnaire survey. appetites assessed visual analog scale (VAS), meal weight time. For quality,...
The impact of radiation-related lymphocyte recovery on prognosis in locally advanced esophageal squamous cell carcinoma (LA-ESCC) remains unclear. Patients with stage II-IVa ESCC who received definitive RT were screened. Collect absolute counts (ALCs) before, during, and after RT. status lymphocytes was observed at one-month post-RT (P1) three months (P3). relatively lower levels P1 divided into Group a those higher b. P3 A B. Kaplan-Merier's analysis Cox conducted to compare survival...
Patients with inflammatory bowel disease, which includes ulcerative colitis and Crohn's are at a significantly increased risk of developing colorectal cancer, aberrant interleukin (IL)-6/STAT3 signaling pathway exists in both disease inflammation-related gastrointestinal cancers. We have previously found that oroxylin A inhibited the NF-κB human colon tumor HCT-116 cells. However, whether could inhibit colitis-associated carcinogenesis remains to be determined. cells were treated various...
Neurological deterioration (ND) shortly after stroke is common in Chinese patients. We aimed to determine the effects of ND during hospitalization on prognosis.We retrospectively reviewed files from registry Department Neurology Tianjin Huanhu Hospital between October 1, 2008, and December 31, 2015. The inclusion criteria were: age ≥18 years, diagnosis acute ischemic stroke, first-ever occurring within 7 days prior admission. was defined as an increase National Institutes Health Stroke Scale...
To investigate the connection between mutant KRAS/NRAS/BRAF and clinicopathological characteristics in therapy-naïve synchronous metastatic colorectal cancer (mCRC) Chinese populations when compared with all wild type (KRAS/NRAS/BRAF type).A total of 200 patients mCRC (TNM stage: TanyNanyM1) were retrospectively collected as study objects. Primary tumor tissues from analyzed through next-generation sequencing panel to assess mutated regions KRAS/NRAS/BRAF.The distribution frequency gene...
Abstract Background Multidrug-resistant organisms (MDROs) have emerged as an important cause of poor prognoses patients in the intensive care unit (ICU). This study aimed to establish easy-to-use nomogram for predicting occurrence MDRO colonization or infection ICU patients. Methods In this study, we developed a based on predictors admitted First Affiliated Hospital Xiamen University from 2016 2018 using univariate and multivariate logistic regression analysis. We externally validated...
Postoperative radiation (PORT) is an option for non-small cell lung cancer (NSCLC) patients with resectable stage IIIA pathological N2 status (pN2). For PORT, this study aims to investigate the impact of exact number positive lymph nodes (LNs) on overall survival (OS) and cancer-specific (LCSS).Within Surveillance, Epidemiology, End Results database, we identified 3373 (pN2) NSCLC who underwent a lobectomy or pneumonectomy from 2004 2013. OS LCSS were compared among coded as receiving PORT...
Objective: To investigate the prevalence of sleep quality and post-traumatic stress disorder (PTSD) symptoms healthcare workers (HCWs) identify determinants for PTSD among HCWs in high-risk low-risk areas during COVID-19 outbreak China. Methods: The Pittsburgh Sleep Quality Index Impact Event Scale were used to assess 421 Chinese HCWs, respectively, from January 30 March 2, 2020. influencing factors identified by univariate analysis multiple regression. Results: incidence getting 13.2%. had...
Faced with increasingly serious fungal infections and drug resistance issues, three different series of novel dual-target (programmed death ligand 1/14 α-demethylase) compounds were constructed through the fragment combination pathway in study. Their chemical structures synthesized, characterized, evaluated. Among them, preferred 10c-1, 17b-1, 18b-2 could efficiently exert their antifungal antidrug-resistant ability blocking ergosterol biosynthesis, inducing upregulation reactive oxygen...
Fruit bagging is a widely used orchard practice in China. Trichothecium black spot (TBS) disease highly associated with the fruit bagging. In this study, we characterized vitro factors affecting causal agent, roseum, and TBS development infection histology on field-bagged apple situ. Under conditions, conidial germination required exogenous nutrients, rate was significantly promoted by high humidity, condition mimicking bag microenvironment. Germ tubes penetrated via natural openings...
The intricate relationship between sleep deprivation (SD) and cognitive performance has long been a subject of research. Our study offers novel angle by closely examining the neurobiological underpinnings sustained attention deficits through lens fronto-parietal network (FPN). Using state-of-the-art imaging techniques, we delve into changes in spontaneous brain activity after SD explore their associations with on psychomotor vigilance task (PVT).We conducted an elaborate investigation...
Background: Chemotherapy impairs ovarian function in premenopausal breast cancer patients. Many patients experience menopause earlier and therefore lose their reproductive abilities. The protective effect of gonadotropin-releasing hormone agonist (GnRha) upon the ovary is clearly apparent for receptor (HR) negative patients, although available data not consistent patient body as a whole when considered regardless HR status. It also unknown whether levels Anti-Mullerian Hormone (AMH) can...
Epstein-Barr virus (EBV) infection may induce immune suppression in several ways, which influence the proper host response to other pathogens and lead a bad outcome of critically ill patients.This was single-center, retrospective, observational study. All patients admitted an ICU because respiratory failure were included. EBV detection from lower tract (LRT) serum samples routinely performed.Twenty-eight consecutive cases who at high-risk for or clinical signs included our Among 28 patients,...
High-sensitivity C-reactive protein (hs-CRP) is not only a marker of inflammation but also prognostic factor for ischemic stroke. The objective our study was to investigative the association between hs-CRP levels and outcomes patients with small-artery occlusion (SAO).We selected 718 participants diagnosed SAO (according Trial Org 10172 in Acute Stroke Treatment classification) using stroke registry Department Neurorehabilitation Tianjin HuanHu Hospital. Hs-CRP values at admission were...
Clear cell renal carcinoma (ccRCC) is the most common and has poor prognosis in locally advanced stage. Ferroptosis, a relatively new type of death, gained significant attention recent years. This study aimed to explore prognostic value ferroptosis-related genes (FRGs) ccRCC. In this study, 50 differentially expressed FRGs between ccRCC adjacent normal kidney tissues were identified, 26 them correlated with overall survival (OS) ( P < 0.05). Eight optimal selected by Lasso regression...
Background The COVID-19 pandemic has a serious impact on the mental health of public due to its economic and social impact. And psychological effects have led drug alcohol abuse. After city lifted lockdown, we consecutively encountered several young nitrous oxide abusers admitted hospital for neurological treatment. Purpose To inform physician decisions intervention, this observational study aimed at investigating characteristics underlying causes during lockdown. Methods who sought...