A5078546314- Antibiotic Resistance in Bacteria
- Vibrio bacteria research studies
- Travel-related health issues
- Salmonella and Campylobacter epidemiology
- Parasitic Infections and Diagnostics
- Pharmaceutical and Antibiotic Environmental Impacts
- Antibiotic Use and Resistance
- Antimicrobial Resistance in Staphylococcus
- Vector-borne infectious diseases
- Parasites and Host Interactions
- Viral Infections and Vectors
- Bacterial Identification and Susceptibility Testing
- Parasite Biology and Host Interactions
- Enterobacteriaceae and Cronobacter Research
- Mosquito-borne diseases and control
- Fungal Infections and Studies
- Neurobiology of Language and Bilingualism
- Escherichia coli research studies
- Malaria Research and Control
- Dermatological diseases and infestations
- Language Development and Disorders
- COVID-19 epidemiological studies
- Reading and Literacy Development
- Streptococcal Infections and Treatments
- Insects and Parasite Interactions
Swiss Tropical and Public Health Institute
2015-2024
University of Basel
2008-2024
University of Zurich
2016-2022
Prevention Institute
2020
Hospital Base
2013-2020
Institute of Social and Preventive Medicine
2016-2017
University Hospital of Basel
2012-2016
International travel contributes to the worldwide spread of multidrug resistant Gram-negative bacteria. Rates travel-related faecal colonization with extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae vary for different destinations. Especially travellers returning from Indian subcontinent show high rates. So far, nothing is known about region-specific risk factors becoming colonized. An observational prospective multicentre cohort study investigated South Asia. Before and...
Stool samples from 38 travelers returning India were screened for extended-spectrum cephalosporin- and carbapenem-resistant Enterobacteriaceae implementing standard selective plates. Twenty-six (76.3%) people colonized with CTX-M or DHA producers, but none of the strains was colistin resistant and/or mcr-1 positive. Nevertheless, using overnight enrichment CHROMagar Orientation plates supplemented colistin, four (10.5%) found to be colistin-resistant Escherichia coli One...
HIV‐infected women are at increased risk of cervical intraepithelial neoplasia (CIN) and invasive cancer (ICC), but it has been difficult to disentangle the influences heavy exposure HPV infection, inadequate screening immunodeficiency. A case‐control study including 364 CIN2/3 20 ICC cases matched 1,147 controls was nested in Swiss HIV Cohort Study (1985–2013). significantly associated with low CD4+ cell counts, whether measured as nadir [odds ratio (OR) per 100‐cell/μL decrease = 1.15, 95%...
BackgroundAntimicrobial resistance is highly prevalent in low-income and middle-income countries. International travel contributes substantially to the global spread of intestinal multidrug-resistant Gram-negative bacteria. Hundreds millions annual visitors countries are all exposed bacteria resulting 30–70% them being colonised at their return. The colonisation process high-exposure environments poorly documented because data have only been derived from before after sampling. We...
Background. Invasive aspergillosis (IA) remains a leading cause of morbidity and mortality in patients receiving allogeneic hematopoietic stem cell transplantation (HSCT). To date, no reliable immunological biomarkers for management outcome IA exist. Here, we investigated reconstitution antifungal immunity during the first 12 months after HSCT correlated it with IA. Methods. Fifty-one were included, 9 probable/proven We determined quantitative qualitative polymorphonuclear (PMN), CD4, CD8,...
Abstract Objectives For low-income countries, data regarding the intestinal colonization with extended-spectrum cephalosporin-resistant (ESC-R) and colistin-resistant (CST-R) Enterobacteriaceae in community are still scarce. Here, we investigated this phenomenon by analysing hotel employees Zanzibar. Methods During June to July 2018, rectal swabs from 59 volunteers were screened implementing selective enrichments agar plates. Species identification was achieved using MALDI-TOF MS. Strains...
This paper discusses challenges in formulating and harmonizing malaria prevention recommendations for travellers. It explores diverse approaches used by advisory groups to assess risk shares insights from the 2023 International Expert Committee Travel Medicine meeting. also future prospects enhancing
The unprecedented increase in number of African refugees arriving Europe is confronting clinicians and general practitioners with the question whether or not how to screen migrants from endemic regions for Schistosoma mansoni infection.We assessed accuracy 3 different diagnostic tests S. infection (stool microscopy [samples prepared by sedimentation technique], serology, point-of-care circulating cathodic antigen [POC-CCA] urine cassette test) 107 newly arrived asymptomatic Eritrean...
We aimed to assess the intestinal colonization dynamics by multiple extended-spectrum cephalosporin-resistant Enterobacteriaceae (ESC-R-Ent) clones in Swiss travelers India, a setting with high prevalence of these multidrug-resistant pathogens. Fifteen healthy volunteers (HVs) colonized ESC-R-Ent after traveling India who provided stools before, after, and at 3- 6-month follow-up are presented this study. Stools were enriched LB broth containing 3 mg/L cefuroxime plated standard selective...
Abstract Objectives Intestinal colonization with extended-spectrum cephalosporin-resistant (ESC-R) and colistin-resistant (CST-R) Enterobacterales (Ent) can be driven by contact colonized animals and/or contamination of the food chain. We studied ESC-R-Ent COL-R-Ent colonizing poultry as well contaminating chicken meat in Zanzibar (Tanzania). Results were compared recently published data obtained from rectal swabs people community. Methods During June July 2018, we collected faecal material...
Antimicrobial resistant (AMR) Enterobacterales are widely distributed among the healthy population of Indochinese peninsula, including Laos. However, local reservoir these pathogens currently not known and possible sources such as agricultural settings food have rarely been analyzed. In this work, we investigated extended-spectrum cephalosporin- (ESC-) colistin-resistant Escherichia coli strains (CST-R- Ec ) isolated from gut people, feces poultry, chicken meat (60 samples each group) in...
Abstract Two MDR Salmonella Typhi isolates from India were found by whole genome sequencing to be closely related the 2016 XDR S. outbreak strain Pakistan. The Indian have no chromosomal antimicrobial resistance cassette but carry IncY plasmid p60006. Both are susceptible chloramphenicol, azithromycin, and carbapenems.
Schistosomiasis, an acute and chronic parasitic disease caused by human pathogenic Schistosoma species, is a neglected tropical affecting more than 220 million people worldwide. For diagnosis of schistosomiasis, stool urine microscopy for egg detection still the recommended method, however sensitivity these methods limited. Therefore, other like molecular DNA in stool, circulating cathodic antigen or anodic serum, as well serological tests have gained attention. This study examines...
Numerous structural studies have established that experience shapes and reshapes the brain throughout a lifetime. The impact of early development, however, is still matter debate. Further clues may come from studying multilinguals who acquired their second language at different ages. We investigated adult spoke three languages fluently, where third was learned in classroom settings, not before age 9 years. Multilinguals exposed to two simultaneously birth (SiM) were contrasted with...
Giardiasis failing nitroimidazole first-line treatment is an emerging problem in returning European travelers. We present data on the efficacy and tolerability of 2 second-line regimens.This prospective, open-label, multicenter study assessed quinacrine monotherapy (100 mg 3 times per day for 5 days) albendazole plus chloroquine combination therapy (400 twice daily 155 nitroimidazole-refractory giardiasis. The defined end points were clinical outcome, at week after parasitological using...