Elena Parlagreco

ORCID: 0000-0003-0368-755X
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About
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Research Areas
  • Neuroendocrine Tumor Research Advances
  • Lung Cancer Research Studies
  • Neuroblastoma Research and Treatments
  • Pancreatic and Hepatic Oncology Research
  • Cancer Diagnosis and Treatment
  • Bladder and Urothelial Cancer Treatments
  • COVID-19 and healthcare impacts
  • Nutrition and Health in Aging
  • Gut microbiota and health
  • Epigenetics and DNA Methylation
  • Cancer Immunotherapy and Biomarkers
  • Urinary and Genital Oncology Studies
  • Lung Cancer Treatments and Mutations
  • Liver Disease Diagnosis and Treatment
  • PARP inhibition in cancer therapy
  • Emergency and Acute Care Studies
  • Prostate Cancer Treatment and Research
  • Advances in Oncology and Radiotherapy
  • Palliative Care and End-of-Life Issues
  • Chronic Disease Management Strategies
  • Myasthenia Gravis and Thymoma
  • Gyrotron and Vacuum Electronics Research
  • Radiopharmaceutical Chemistry and Applications
  • Brain Metastases and Treatment
  • Renal cell carcinoma treatment

Azienda Sanitaria Ospedaliera S.Croce e Carle Cuneo
2023-2025

Ospedale San Luigi Gonzaga
2020-2024

Azienda Ospedaliera Universitaria Università degli Studi della Campania Luigi Vanvitelli
2024

Ospedale degli Infermi
2024

University of Turin
2020-2023

Gonzaga University
2022

During the last decade, a new therapeutic revolution has involved management of hepatocellular carcinoma (HCC). This is made possible thanks to documented efficacy immunotherapy for this disease. In addition, evidence demonstrated role gut-liver axis and gut microbiota in host homeostasis, tumor development, response therapies. particular, intestinal dysbiosis can alter microenvironment leading activation intracellular signalling pathways that promote carcinogenesis. The composition proved...

10.20944/preprints202501.1782.v1 preprint EN 2025-01-23

During the last decade, a new therapeutic revolution has involved management of hepatocellular carcinoma (HCC). This is made possible thanks to documented efficacy immunotherapy for this disease. In addition, evidence demonstrated role gut–liver axis and gut microbiota in host homeostasis, tumor development, response therapies. particular, intestinal dysbiosis can alter microenvironment, leading activation intracellular signaling pathways that promote carcinogenesis. The composition proved...

10.3390/onco5010009 article EN cc-by Onco 2025-02-27

Well-differentiated lung neuroendocrine tumors (Lu-NET) are classified as typical (TC) and atypical (AC) carcinoids, based on mitotic counts necrosis. However, prognostic factors, other than tumor node metastasis (TNM) stage the histopathological diagnosis, still lacking. The current study is aimed to identify potential factors better stratify NET, thus, improving patients' treatment strategy follow-up.A multicentric retrospective study, including 300 Lung all surgically removed, from...

10.1007/s12020-022-03015-w article EN cc-by Endocrine 2022-03-18

Neuroendocrine carcinomas (NECs) are poorly differentiated and highly aggressive epithelial neuroendocrine neoplasms. The most common primary site is the lung, but they may arise in every organ. Approximately 37% of extrapulmonary NECs (EP-NECs) occur gastroenteropancreatic (GEP) tract, followed by genitourinary (GU) system gynecological tract. As a result their rarity, there scant evidence to guide treatment recommendations, multidisciplinary approach essential for management such patients....

10.3390/jcm12247715 article EN Journal of Clinical Medicine 2023-12-15

Hospital admission (HA) in cancer history is a common, repeated and frequently unplanned event. The emergency departments (EDs) the oncological outpatient service (OOS) are ordinary way of entry. We studied reasons admission, pathways access discharge prognostic factors population admitted patients with cancer.The health records ward referral hospital 6-month period were retrieved analysed. characteristics those last 3 months life compared other group.Among 147 HA, 79.5% unplanned, 48.9%...

10.1136/spcare-2023-004574 article EN BMJ Supportive & Palliative Care 2023-09-13

<title>Abstract</title> Purpose Approximately a 70% of lung cancer (LC) patients experience malnutrition. Therefore, rapid and functional nutritional assessment is needed. Several screening instruments are available for clinical use. This study aimed to compare the Nutritional Risk Screening − 2002 (NRS-2002) Malnutrition Tool (MST) assess malnutrition in LC patients. Methods MST, NRS-2002, quality life (QoL) Handgrip Test were performed at baseline (T0), day 30th (T1) 90th (T2). The...

10.21203/rs.3.rs-3958544/v1 preprint EN cc-by Research Square (Research Square) 2024-03-19

Radium 223 (Ra-223) was approved for the treatment of metastatic castration resistant prostate cancer (mCRPC) patients with bone-only disease, following demonstration significant improvement in overall survival (OS). To date, there are no validated prognostic factors useful predicting outcome mCRPC treated Ra-223. Our retrospective study aims to evaluate role discontinuation due adverse events Ra-223, and identify which correlate toxicity onset.We performed a analysis all consecutive Ra-223...

10.1177/03008916221077144 article EN Tumori Journal 2022-03-31

Since SARS-CoV-2 infection rapidly spread around the world, Italy has quickly become one of most affected countries. Healthcare systems introduced strict control measures to ensure optimal care, especially in frail groups such as cancer patients (pts). This study investigated efficacy pre-procedure screening and whether COVID-19 influenced timely diagnosis therapy.Data oncological procedures pts with confirmed or suspected diagnosis, treated at Oncology Department coming from Emergency San...

10.37349/etat.2021.00058 article EN cc-by Exploration of Targeted Anti-tumor Therapy 2021-10-31

Safety data regarding BNT162b2 in cancer patients (CPs) are scarce. Herein we report the side effects (SEs), adverse events (AEs), and patient-reported outcomes (PROs) following administration CPs treated at San Luigi Gonzaga University Hospital. All who agreed to participate our vaccination campaign received were included descriptive analysis. An anonymous questionnaire investigating occurrence of SEs/AEs PROs was administered study population 21 days after first dose. Pearson's chi-squared...

10.3390/biomedicines11010165 article EN cc-by Biomedicines 2023-01-09

Abstract Purpose Well-differentiated lung neuroendocrine tumors (Lu-NET) are classified as typical (TC) and atypical (AC) carcinoids, based on mitotic counts necrosis. However, prognostic factors, other than tumor node metastasis (TNM) stage the histopathological diagnosis, still lacking. The current study is aimed to identify potential factors better stratify NET, thus, improving patients’ treatment strategy follow-up. Methods A multicentric retrospective study, including 300 Lung all...

10.21203/rs.3.rs-1193325/v1 preprint EN cc-by Research Square (Research Square) 2022-01-05

Background: Glucagonoma is a rare functional pancreatic neuroendocrine tumor. Necrolytic migratory erythema (NME) paraneoplastic manifestation of glucagonoma and often the first presenting symptom. The misdiagnosis this entity can affect patient’s quality life his expectancy. Case Presentation: We report case 48-year-old man with pruritic scaly rash, ulcerated skin lesions, periorbital edema, who was diagnosed treated for atopic eczema 7-year period. Despite treatment, dermatitis general...

10.24911/ejmcr/173-1606402831 article EN European Journal of Medical Case Reports 2021-01-01
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