A5012431557- Genetics and Physical Performance
- Muscle metabolism and nutrition
- Cardiovascular and exercise physiology
- Adipose Tissue and Metabolism
- MicroRNA in disease regulation
- Cardiovascular Disease and Adiposity
- Cardiac pacing and defibrillation studies
- Renin-Angiotensin System Studies
- Hormonal Regulation and Hypertension
- Tissue Engineering and Regenerative Medicine
- Biomedical Ethics and Regulation
- Electrospun Nanofibers in Biomedical Applications
- Histone Deacetylase Inhibitors Research
- Circular RNAs in diseases
- Cardiovascular Effects of Exercise
- ATP Synthase and ATPases Research
- Exercise and Physiological Responses
- Gastrointestinal motility and disorders
- Extracellular vesicles in disease
- Heart Failure Treatment and Management
- Diet and metabolism studies
- Apelin-related biomedical research
- Health, Nursing, Elderly Care
- Palliative and Oncologic Care
- Mesenchymal stem cell research
Universidade de São Paulo
2005-2022
Aerobic exercise-induced cardiac hypertrophy (CH) is a physiological response involving accurate orchestration of gene and protein expression contractile metabolic components. The microRNAs: miR-208a, miR-208b miR-499 are each encoded by myosin thus also known as 'MyomiRs', regulating several mRNA targets that in turn regulate CH pathways. To understand the role myomiRs fine-tuning heavy chain (MHC) isoform exercise training-induced hypertrophy, Wistar rats were subjected to two different...
Polymorphisms of the angiotensin converting enzyme (ACE) gene can interfere with exercise-induced acute blood pressure (BP) reduction. This cross-over study investigated effect a single walk on BP and tested whether polymorphisms ACE might explain variation in responses.Thirty-four healthy medicated individuals were randomized to one control walking session at 60-75% heart rate reserve. Subjects left laboratory wearing an ambulatory monitor until waking next morning.Overall, systolic was...
Functional variants of angiotensin-converting enzyme (ACE) gene may be associated with response to therapy in patients heart failure (HF).To test the hypothesis differences sequential echocardiographic evaluations left ventricular ejection fraction HF on medical therapy, including ACE inhibitors relation insertion (I) / deletion (D) polymorphism gene.We studied 168 (mean age 43.3+/-10.1 years), 128 (76.2%) men, and echocardiograms. The I/D was determined by polymerase chain reaction. Left...
Montrezol, FT, Marinho, R, Mota, GdFAd, D'almeida, V, de Oliveira, EM, Gomes, RJ, and Medeiros, A. ACE gene plays a key role in reducing blood pressure the hyperintensive elderly after resistance training. J Strength Cond Res 33(4): 1119-1129, 2019-Hypertension is difficult disease to control exercise training hypertension control. Some individuals are not responsive training; so, we highlight polymorphism of I allele angiotensin-converting enzyme (ACE) as factor responsible for this lack...
Introduction: Previous studies have linked angiotensin-converting enzyme ( ACE) insertion (I)/deletion (D) polymorphism (II, ID and DD) to physical performance. Moreover, ACE has two catalytic domains: NH2 (N) COOH (C) with distinct functions, their activity been found be modulated by polymorphism. The aim of the present study is investigate effects interaction between aerobic exercise training (AET) I/D on N- C-domain activities vascular reactivity in humans. Materials methods: A total 315...
Summary The renin‐angiotensin aldosterone system ( RAAS ) is associated with diverse physiological responses and adaptations to exercise. angiotensin converting enzyme ACE 2 has vasodilatory effects, which might be the blood pressure BP acute aim of this study was investigate role polymorphisms in postexercise hypotension PEH ). Thirty‐four medicated hypertensive (61·3 ± 1·7 years, 76·1 2·7 kg, 160 1·6 cm) men n = 12) women 22), participated a control moderate intensity exercise session...
Aerobic exercise training (ET) produces beneficial adaptations in skeletal muscles, including angiogenesis. The renin-angiotensin system (RAS) is highly involved angiogenesis stimuli. However, the molecular mechanisms underlying capillary growth muscle induced by aerobic ET are not completely understood. This study aimed to investigate effects of volume-dependent on involving expression miRNAs-27a and 27b RAS oxidant-antioxidant balance. Eight-week-old female Wistar rats were divided into...
‐We investigated the effect of aerobic swimming exercise training in vascular remodeling alterations coronary artery from SHR and microRNA expression patterns. All animal care experimental procedure were accordance with National Institutes Health Guidelines for Care Use Laboratory Animals approved by local ethics committee University São Paulo (N° 2013/01). The groups (n=40) consisted three‐month‐old male normotensive rats Wistar Kyoto (WKY), trained (SHR‐t) on a protocol 10 weeks (60 min/...