ABSTRACT Diabetes mellitus is a chronic disease that has been associated with memory loss, neurological disorders, and Alzheimer's disease. Some studies show the importance of physical exercise to prevent minimize various disorders. It believed positive effects on brain functions are mediated by insulin insulin‐like growth factor‐1 (IGF‐1) signaling. In this study, we investigate role swimming training hippocampus proteins related insulin/IGF‐1 signaling pathway in Type 1 diabetic rats its...

To maintain euglycemia in healthy organisms, hepatic glucose production is increased during fasting and decreased the postprandial period. This whole process supported by insulin levels. These responses are associated with signaling pathway reduction activity of key gluconeogenic enzymes, resulting a decrease production. On other hand, defects liver might promote inadequate suppression gluconeogenesis, leading to hyperglycemia after meals. The hepatocyte nuclear factor 4, transcription...

Our aim was to analyze and compare the effects of three different long-term treatments on anthropometric profiles, eating behaviors, anxiety depression levels, quality life groups adults with obesity. Methods: The 43 participants in study were randomly assigned one groups: education health group (EH, n = 12), which received lectures topics; physical exercise (PE, 13), underwent training; interdisciplinary therapy plus cognitive behavioral (IT + CBT) ( 18) group, training, nutritional advice,...

The present study investigated the role of swimming training on cerebral metabolism and hippocampus concentrations insulin IGF-1 in diabetic rats. Wistar rats were divided sedentary control (SC), trained (TC), (SD), (TD). Diabetes was induced by Alloxan (35 mg kg(-1) b.w.). Training program consisted 5 days/week, 1 h/day, 8 weeks, supporting a load corresponding to 90% maximal lactate steady state (MLSS). For MLSS determination, submitted three sessions 25-min loads 4, 5, or 6% body wt, with...

To investigate the alterations of glucose homeostasis and variables insulin-like growth factor-1 (IGF-1) system in sedentary trained diabetic (TD) rats, Wistar rats were divided into control (SC), (TC), (SD), TD groups. Diabetes was induced by Alloxan (35 mg kg(-1) b.w.). Training program consisted swimming 5 days week(-1), 1 h day(-1), during 8 weeks. Rats sacrificed blood collected for determinations serum glucose, insulin, hormone (GH), IGF-1, IGF binding protein-3 (IGFBP-3). Muscle liver...

To investigate the influence of short-term physical training on IGF-I concentrations in diabetic rats, male wistar rats were distributed into four groups: sedentary control, trained and diabetic. Diabetes was induced by Alloxan (32 mg/kg b.w.) protocol consisted swimming 1 h/day, 5 days/week, during 4 weeks, supporting 5% b.w. At end this period, sacrificed blood collected for determinations serum glucose, insulin, albumin, hematocrit. Liver samples used to determine glycogen, protein, DNA...

Introduction: Hypertension is the most common disease in industrialized countries, and it responsible for major risk factor developing cardiovascular diseases. Aging increases prevalence of hypertension loss muscle mass. The aim present study was to evaluate effect resistance training on blood pressure inflammatory markers hypertensive elderly. Methods: One hundred thirty-five elderly were distributed into two groups: (TG, n=86), control (CG, n=49). TG underwent 16 weeks with three sets 12...

Montrezol, FT, Marinho, R, Mota, GdFAd, D'almeida, V, de Oliveira, EM, Gomes, RJ, and Medeiros, A. ACE gene plays a key role in reducing blood pressure the hyperintensive elderly after resistance training. J Strength Cond Res 33(4): 1119-1129, 2019-Hypertension is difficult disease to control exercise training hypertension control. Some individuals are not responsive training; so, we highlight polymorphism of I allele angiotensin-converting enzyme (ACE) as factor responsible for this lack...

Epidemiological studies indicate continuous increases in the prevalence of Alzheimer's Disease (AD) next few decades. The key feature this disease is hippocampal neurodegeneration. This structure has an important role learning and memory. Intense research efforts have sought to elucidate neuroprotective mechanisms responsible for integrity. Insulin signaling seems be a very promising pathway prevention treatment AD. hormone been described as powerful activator neuronal survival. Recent...

To investigate the effects of a specific protocol undulatory physical resistance training on maximal strength gains in elderly type 2 diabetics.The study included 48 subjects, aged between 60 and 85 years, both genders. They were divided into two groups: Untrained Diabetic Elderly (n=19) with those who not subjected to Trained (n=29), training. The participants evaluated several types training's equipment before after protocol, by test one repetition. subjects trained three times per week...

Diabetic cardiomyopathy contributes to the high incidence of mortality in both types diabetes. We aimed investigate histochemical aspects collagen and reticular fibers cardiac muscle evaluate influence physical exercise on these aspects. Wistar rats were divided 4 groups: sedentary control (SC), trained (TC), diabetic (SD) (TD). Diabetes was induced with alloxan (35 mg/kg). Training program consisted swimming 1h/day a load 4.8% body weight for TD 5.2% TC, during 8 weeks. At end experiment,...

Dado que o diabetes mellitus é considerado um problema de saúde pública mundial, presente estudo objetivou avaliar a tolerância à glicose oral (TTGo) e concentrações insulina pancreática (CIP) ratos diabéticos tipo 1 submetidos protocolo treinamento físico individualizado.Foram utilizados 40 Wistar adultos, onde metade foi induzida ao por meio injeção endovenosa aloxana (32 mg/kg), divididos em quatro grupos (10 grupo): Controle Sedentário (CS), Treinado (CT), Diabético (DS) (DT).O consistiu...

Manual resistance training (MRT) is a low cost and practically applicable alternative form of that ideal for weight rooms with limited equipment. The aim this study was to compare the acute subacute hemodynamic responses between MRT free (FWRT) in normotensive (NT) hypertensive (HT) men.Twenty-six untrained men performed single bout FWRT minimum 72-hour rest between. Systolic blood pressure (SBP), diastolic (DBP), mean (MBP) were measured, double product (DP) calculated. Variables assessed...

Background: Association between obesity, interdisciplinary therapy and intense physical exercise was described for obese patients. However, the study of activities representing daily tasks cardiovascular risk in everyday becomes necessary to verify occurrence this association. Objective: To investigate whether a period 18 weeks is capable promoting benefits parameters at rest during adults. Methods: Sample 32 individuals both sexes with body mass index 30 39.9 kg/m2 age 50 years....

Background: Aerobic physical exercise influences several aspects of diabetic pathology, including cardiomyopathy development. The experimentally-induced rat model has contributed to advances in this line research. Objective: aim the present study was examine effects moderate aerobic training on metabolic, histological and ultra structural myocardium experimental rats. Methods: Wistar rats were divided into 4 groups, sedentary control (SC), trained (TC), (SD) (TD). Diabetes induced by Alloxan...