A5070932288- Adrenal and Paraganglionic Tumors
- Hormonal Regulation and Hypertension
- Cancer, Hypoxia, and Metabolism
- Pituitary Gland Disorders and Treatments
- Neuroendocrine Tumor Research Advances
- Diabetes Management and Research
- Diabetes Treatment and Management
- Parathyroid Disorders and Treatments
- Medical Imaging and Pathology Studies
- Pancreatic function and diabetes
- Sexual Differentiation and Disorders
- Lymphoma Diagnosis and Treatment
- Cancer, Lipids, and Metabolism
- Diet and metabolism studies
- Liver Disease Diagnosis and Treatment
- Bone health and treatments
- CNS Lymphoma Diagnosis and Treatment
- Lipid metabolism and disorders
- Artificial Intelligence in Healthcare
- Hormonal and reproductive studies
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Cancer-related molecular mechanisms research
- Thyroid and Parathyroid Surgery
- Molecular Biology Techniques and Applications
Chinese PLA General Hospital
2012-2024
Tianjin Chest Hospital
2024
Chinese People's Liberation Army
2016-2022
PLA Academy of Military Science
2022
Chinese General Hospital College of Nursing and Liberal Arts
2022
Fudan University
2019
Second Military Medical University
2019
Changhai Hospital
2019
The Military General Hospital of Beijing PLA
2013
Abstract Umbilical cord-derived mesenchymal stem cells (UC-MSCs) have been proved a promising clinical strategy for the treatment of diabetes, and time in range (TIR) has demonstrated new metric glycemic control links to diabetes complications. To further assess therapeutic effect UC-MSCs on TIR, phase II study investigating efficacy Chinese adults with type 2 (T2D) assessed by retrospective continuous glucose monitoring (CGM) was conducted. In this randomized placebo-controlled trial, total...
Studies have demonstrated the relationship between fatty liver index (FLI) and metabolism, while few research reported its with hyperuricemia (HUA). This study aimed to predict HUA by determining baseline FLI events validating FLI-HUA correlation through follow-up.This was a community-based cohort involving 8851 adults in China. We performed anthropometric assessments analyzed follow-up blood samples. defined as uric acid level of > 420 µmol/L (7 mg/dL).Patients had higher prevalence...
Functional pancreatic neuroendocrine neoplasms (PanNENs) are very rare disorders but have complex spectrum, including insulinoma, gastrinoma, glucagonoma, somatostatinoma, and VIPoma. Patients with PanNENs usually present characteristic symptoms caused by corresponding hormone hypersecretion. It has always been challenging in dealing such complicated disorders. In this report, we analyzed the clinical characteristics of functional a large cohort Chinese patients summarized our experience...
Kallmann syndrome, a form of idiopathic hypogonadotropic hypogonadism, is characterized by developmental abnormalities the reproductive system and abnormal olfaction. Despite association certain genes with genetic inheritance expression are complex incompletely known. In present study, seven syndrome pedigrees in an ethnic Han Chinese population were screened for mutations. The exons intron–exon boundaries 19 hypogonadism (idiopathic hypogonadism)-related sequenced. Detected mutations also...
Primary bilateral macronodular adrenocortical hyperplasia (PBMAH) is a rare condition with untypical subclinical symptoms of Cushing's syndrome (CS). This study aimed to compare the clinical and pathological features PBMAH unilateral cortisol-secreting adrenal adenoma (UAA).We prospectively included 46 patients 205 UAA from January 2000 February 2014. Cortisol levels 24 hours urine free cortisol (UFC) were determined at baseline during dexamethasone suppression test (DST) using...
We aimed to investigate the effects of prediabetes and its phenotypes impaired fasting glucose (IFG), tolerance (IGT) elevated glycated hemoglobin A
Non-Hodgkin's lymphoma (NHL) can involve extralymphatic organs, resulting in diverse clinical manifestations, especially if the endocrine organs are affected. This type of involvement often be difficult to detect accurately. Until now, no patients with NHL and concomitant bilateral adrenal hypothalamic have been reported. The purpose this article is discuss diagnosis treatment gland so as help physicians avoid misdiagnosis missed diagnosis.We describe a case 52-years-old male patient masses,...
Objective To analyze the clinical characteristics of pituitary stalk interruption syndrome(PSIS). Methods The data including manifestations,laboratory tests,and imaging findings 114 PSIS patients in our hospital were retrospectively analyzed. Results Of these patients,102 cases (89.4%) male. average age was 21.1?6.1 years. A history breech delivery documented 91 (91.9%). Short stature found 89 (71.8%) and bone delayed (6.1?5.1) Secondary sex poor or undeveloped most patients. prevalence...
Long noncoding RNAs (lncRNAs) can regulate the expression of genes at almost every level. The altered lncRNAs was observed in many kinds cancers. Until recently, few studies have focused on function context papillary thyroid carcinoma (PTC).In current study, we collected seven PTC and nodular goiter tissue samples explored mRNA lncRNA patterns these by microarray.We aberrant 94 99 mRNAs as compared to [fold change (FC) ≥2.0; P<0.01]. To confirm microarray results, quantitative polymerase...
In the present study, case of a female patient with pseudo‑hermaphrodism caused by an androgen‑producing adrenocortical tumor is presented, and possible mechanism investigated. The expression luteinizing hormone/human chorionic gonadotrophin (LH/hCG) receptor in tissues normal adrenal was analyzed using immunohistochemistry. Furthermore, activities 3β‑hydroxysteroid dehydrogenase 2 (HSD2), cytochrome P450 17α‑hydroxylase (CYP17) 17β‑hydroxysteroid 3 (HSD3) enzymes were measured enzyme‑linked...
Abstract Context Intraoperative hemodynamic instability (HI) deteriorates surgical outcomes of patients with normotensive pheochromocytoma (NP). Objective To characterize the hemodynamics NP and develop externally validate a prediction model for intraoperative HI. Methods Data on 117 (derivation cohort) 40 adrenal myelolipoma (NAM) who underwent laparoscopic adrenalectomy from January 2011 to November 2021 were retrospectively collected. 22 (independent validation collected another hospital...
Background Castleman Disease (CD) is a group of diseases with characteristic lymph node histopathology, characterized by marked enlargement deep or superficial nodes. Adrenal CD rarely reported, and an accurate preoperative diagnosis adrenal difficult. Method We report four cases in the gland confirmed pathology review characteristics this rare disease, highlighting necessity diagnostic evaluation follow-up patients. Results All patients sought medical advice because incidentalomas. No...
Abstract We describe an elderly male patient who presented with fever of unknown origin and refractory hyponatraemia. Following 18 fluorine‐fluorodeoxyglucose positron emission tomography/computed tomography scan core adrenal biopsy, the diagnosis diffuse large B‐cell non‐Hodgkin lymphoma pituitary bilateral involvement was confirmed. After chemotherapy, his symptoms resolved, all lesions shrank significantly.
Abstract Background Patients with type 2 diabetes mellitus (T2DM) usually have higher blood viscosity attributed to high glucose that can decrease supply the pancreas. A mild increase in pressure (BP) has been reported as a potential compensatory response maintain perfusion islet. However, how BP influences beta-cell function T2DM subjects remains inconsistent. This study aimed examine relationship between and patients under different HbA1c levels. Methods is cross-sectional of 615 patients,...
Craniopharyngiomas and germinomas are both rare cranial tumors that most commonly present during childhood or adolescence. Although these have different origins, their clinical radiological features may be similar. In this article, we report the case of a 35-year female patient with findings increased human chorionic gonadotrophin (HCG) levels in cerebrospinal fluid (CSF) were consistent germinoma; however, pathological analysis revealed craniopharyngioma. This highlights HCG, which is...
To study the relationship between hemoglobin glycation index (HGI) and blood lipid indices such as low-density lipoprotein cholesterol (LDL-C), non-high-density (non-HDL-C), plasma atherogenic (AIP).