A5059423906- Aortic Disease and Treatment Approaches
- Aortic aneurysm repair treatments
- Cardiac Valve Diseases and Treatments
- Infectious Aortic and Vascular Conditions
- Infective Endocarditis Diagnosis and Management
- Cardiac Structural Anomalies and Repair
- Congenital Heart Disease Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac and Coronary Surgery Techniques
- Coronary Artery Anomalies
- Tracheal and airway disorders
- Trauma Management and Diagnosis
- Gallbladder and Bile Duct Disorders
- Respiratory Support and Mechanisms
- Appendicitis Diagnosis and Management
- Renal and Vascular Pathologies
- Pulmonary Hypertension Research and Treatments
- Cardiac pacing and defibrillation studies
- Cardiac tumors and thrombi
- Vascular Anomalies and Treatments
- Urological Disorders and Treatments
- Cardiac Arrest and Resuscitation
- Intracranial Aneurysms: Treatment and Complications
- Syphilis Diagnosis and Treatment
- Neonatal Respiratory Health Research
Yokohama City University
2014-2025
Fujisawa City Hospital
2022-2024
Yokohama City University Hospital
2022
Yokohama City University Medical Center
2012-2021
Onomichi General Hospital
2017-2019
KU Leuven
2017-2019
Universitair Ziekenhuis Leuven
2017-2018
Yokohama Municipal Citizen's Hospital
2014-2016
Saiseikai Ibaraki Hospital
2009
Georgia Institute of Technology
2003
Intramural haematoma is defined pathologically as aortic dissection without an intimal tear. We therefore believe that this term inappropriate acute clinical diagnosis, and instead, use the 'thrombosed-type dissection'. compared features of thrombosed-type with those classic dissection. Thrombosed type was flow in false lumen aorta on contrast-enhanced computed tomography. Surgery indicated for all cases A dissection, central repair operations were performed 509 patients. retrospectively...
We reviewed the treatment outcomes for aortic arch aneurysms in elderly patients aged > 80 years, and discussed risk factors each technique. Octogenarians who underwent aneurysm repair between 2007 2021 were included. Fifty-four (23 total replacement [TAR] group 31 thoracic endovascular [TEVAR] group) included study. The early- mid-term all-cause mortality examined group. To examine timely surgical outcomes, cases of true included, whereas dissected emergency due to rupture or other causes...
Excessive prostaglandin E2 production is a hallmark of abdominal aortic aneurysm (AAA). Enhanced expression receptor EP4 (prostaglandin E 4) in vascular smooth muscle cells (VSMCs) has been demonstrated human AAAs. Although moderate contributes to homeostasis, the roles excessive pathology remain uncertain. We aimed investigate whether overexpression VSMCs exacerbates Approach and Results: constructed mice with overexpressed selectively under an SM22α promoter (EP4-Tg). Most EP4-Tg died...
The purpose of this study was to evaluate the clinical outcomes emergency surgery for acute type B aortic dissection with rupture and compare results between open thoracic endovascular repair (TEVAR).Two hundred ninety-four patients were admitted our hospital January 2000 March 2012. At presentation, 30 (10%) had (20 men, 10 women; mean age, 71 ± 15 years), among whom 23 underwent surgery: 9 TEVAR 14 surgery. objective closure primary entry site secondary tear in descending aorta.In group,...
Abdominal aortic aneurysm (AAA) is a life-threatening disease, and no disease-specific circulating biomarkers for AAA screening are currently available. We have identified smooth muscle cell (SMC)-specific biomarker AAA. cultured aneurysmal tunica media that were collected from eight patients undergoing elective open-repair surgeries. Secreted proteins in culture medium subjected to liquid chromatography/tandem mass spectrometry. Myosin heavy chain 11 (myosin-11) was as SMC-specific protein...
Background We evaluated clinical outcomes of thoracic endovascular aortic repair (TEVAR) for ruptured descending aneurysm (rDTAA). Methods Twenty-three patients with rDTAA (mean age, 76.8 ± 8.8 years) underwent TEVAR at our center between January 2008 and April 2013. Results In twenty-three patients, five (21.7%) were in shock before surgery. Technical success was achieved 21 patients. After TEVAR, retrograde Type A dissection occurred one patient, I endoleak II three The 30-day mortality...
Abdominal aortic aneurysm (AAA) is a progressive disease that has an increasing prevalence with aging, but no effective pharmacological therapy to attenuate AAA progression currently available. We reported the prostaglandin E receptor EP4 plays roles in progression. Here, we show effect of CJ-42794, selective antagonist, on using two mouse models (angiotensin II- and CaCl2-induced AAAs) human smooth muscle cells isolated from tissue. Oral administration CJ-42794 (0.2 mg/kg per day) for 4...
This study investigated the optimal timing and usefulness of early cholecystectomy for acute cholecystitis in patients with comorbid cholangitis.In 2011-2016, 252 who underwent 7 delayed were enrolled compared. Patients cholangitis then divided into those urgent (within 72 h after symptom onset), semi-urgent (3-14 days or (3 months onset).There no significant intergroup differences postoperative complication rate (p = 0.561), operation time 0.496), intraoperative blood loss 0.151) between...
It is well known that there are major differences between the Japanese and Western population regarding incidence of ischemic heart disease stroke. The purpose this study was to evaluate patients' characteristics Belgian cohort with acute type A aortic dissection. In 487 patients (297 male patients, mean age 61.9 ± 12.2 yrs) who underwent surgery for dissection, baseline preoperative intraoperative data were collected. (n = 237) compared 250). Clinical included patient demographics, history,...
Patients with a single ventricle survive thanks to the Fontan palliation. Nevertheless, there is growing number of patients progressive heart failure. To validate therapeutic options in these patients, we developed chronic large animal model.A circulation was surgically created 15 sheep. The superior vena cava anastomosed end-to-side pulmonary artery. inferior connected artery by an ePTFE conduit, and cava-right atrium junction ligated.Total cavopulmonary connection successfully performed...
Coronary subclavian steal syndrome associated with upper extremity arteriovenous fistula is an uncommon but potentially life-threatening condition. We present a case of 65-year-old male on hemodialysis left who underwent coronary revascularization involving bypass the internal thoracic artery to anterior descending artery. Intraoperative transit-time graft flow measurements and fluorescence imaging showed reversed in artery, was successfully converted as free from ascending aorta doi:...
Abstract Background We report a one-stage surgery to the case of secondary aortoenteric fistula (sAEF) after prosthetic reconstruction abdominal aortic aneurysm, by multifaceted approach. Case presentation A 63-year-old male was admitted our unit under diagnosed sAEF and pseudoaneurysm thoracoabdominal aorta due infection. The patient underwent emergency operation. Firstly, we placed in modified right lateral decubitus position performed replacement with retroperitoneal approach...
Stanford type A acute aortic dissection (A-AAD) extends to the brachiocephalic branches in some patients. After ascending replacement, a remaining re-entry tear distal may act as an entry and result patent false lumen arch. However, effect of branch concomitant with A-AAD remains unknown.Methods Results:Eighty-five patients who underwent replacement which both preoperative postoperative multiple-detector computed tomography (MDCT) scans could be evaluated were retrospectively studied. The...
Objective Postoperative stroke is a serious unsolved complication after acute type A aortic dissection (ATAAD) repair. We investigated the incidence and risk factors of stroke, hypothesized that supra-aortic vessels an important factor this morbidity. Methods Between 2012 2019, 202 (56% men, median age 68 years) patients with ATAAD underwent surgical Clinical data, image findings, method circulatory support, repair technique were retrospectively to explore postoperative stroke. Results Of...
Tracheo-innominate artery fistula (TIF) is a rare but fatal complication occurring after tracheotomy. Brachiocephalic trunk transection, one of the surgical treatments for TIF, mostly associated with full or partial median sternotomy. We describe case TIF continuous bleeding, which was successfully treated brachiocephalic transection through collar incision without need sternotomy.Case 1. An 18-year-old man referred to our hospital bleeding from tracheal stoma, had ceased prior admission....
To study mid-term outcomes in patients admitted to receive treatment for acute type B aortic dissection.The group comprised 229 with dissection treated between January 2000 and July 2010. 128 had a thrombosed false lumen, 101 patent lumen.In the group, 6 rupture, 4 malperfusion, 118 no complications. There were 5 early deaths (3.9%). In 12 19 70 (5.9%). Overall survival rates 94.7 ± 2.2% 90.2 3.2% at 1 year, 84.3 4.6% 85.9 4.3% years (p = 0.892), respectively. Aorta-related event-free 85.6...