- Heavy Metal Exposure and Toxicity
- Trace Elements in Health
- Dementia and Cognitive Impairment Research
- Radioactivity and Radon Measurements
- Diabetes Management and Education
- Nutrition and Health in Aging
- Heavy Metals in Plants
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Functional Brain Connectivity Studies
- Chronic Disease Management Strategies
- Mobile Health and mHealth Applications
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Selenium in Biological Systems
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Memory and Neural Mechanisms
- Youth, Drugs, and Violence
- Nuclear Physics and Applications
- Public Health in Brazil
- Linguistics and Language Studies
- Health Literacy and Information Accessibility
- Treatment of Major Depression
- Immune Cell Function and Interaction
- Health Systems, Economic Evaluations, Quality of Life
- Olfactory and Sensory Function Studies
- Dental Health and Care Utilization
Universidade de São Paulo
2007-2022
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2012-2020
Cambridge University Press
2010
New York University Press
2010
Studies have shown that various antioxidants are decreased in different age-related degenerative diseases and thus, oxidative stress would a central role the pathogenesis of many disorders involve neuronal degeneration, including Alzheimer's disease (AD). The present study aimed to assess nutritional status Se AD patients compare with control subjects normal cognitive function. case–control was carried out on group elderly ( n 28) compared 29), both aged between 60 89 years. intake evaluated...
Objective: The purpose of the present study was to investigate influence that education and depression have on performance elderly people in neuropsychological tests.Methods: conducted at Institute Psychiatry, University São Paulo School Medicine, Hospital das Clínicas. All individuals evaluated were aged 60 or older. sample consisted 59 outpatients with depressive disorders 51 healthy controls. We stratified by level education: low = 1–4 years schooling; high 5 more schooling. Evaluations...
Substantial medical research has established an inverse relationship between quality of life and illness. However, there exists minimal evidence for such a connection in the context stable controlled diseases.We wished to correlate multimorbidity with elderly patients who suffer from chronic used tool evaluate life, namely World Health Organization life-BRIEF, together scale known as Cumulative Illness Rating Scale - Geriatric Version. Furthermore, data were correlated scores recorded on...
Hospital malnutrition is estimated to affect as many one in two patients at admission, while others develop throughout hospitalization. Despite being a common and long-standing problem among older adults, it often unrecognized associated with increased use of resources negative outcomes such complications, length stay mortality. Nutritional screening assessment are readily available inexpensive procedures that provide crucial information nutrition care plans. These plans should determine the...
There is a growing number of elderly kidney transplant (Ktx) recipients. Elderly recipients present lower acute rejection rates but higher incidence infection and malignancies. Aging per se seems to result in shift memory profile chronic disease (CKD) premature immunological aging. Understanding aging CKD effects on the immune system can improve Ktx immunosuppression. We analyzed system, comparing healthy adults (HAd) (n=14, 26±2y), (HEld) (n=15, 79±7y), end stage renal (ESRD) (EnAd) (n=18,...
<b><i>Background/Aims:</i></b> Oxidative stress plays a central role in Alzheimer’s disease (AD). Pro198Leu cytosolic glutathione peroxidase (GPx1) polymorphism seems to be associated with lower activity of this enzyme, but there are no studies AD patients. Thus, the aim was determine frequency GPx1 patients and verify its relation (GPx) selenium (Se) status. <b><i>Methods:</i></b> The study carried out group elderly (n = 28) compared control...
ABSTRACT Objective To translate, adapt and evaluate the properties of a Brazilian Portuguese version Spoken Knowledge in Low Literacy Patients with Diabetes, which is questionnaire that diabetes knowledge. Methods A cross-sectional study type 2 patients aged ≥60 years, seen at public healthcare organization city Sao Paulo (SP). After development version, we evaluated psychometrics association sociodemographic clinical variables. The regression models were adjusted for data, functional health...
Objective: To investigate the association between inadequate functional health literacy, considering Short Assessment of Health Literacy for Portuguese-speaking Adults, and glycemic control in elderly patients with type 2 diabetes, to examine this low social support settings, according Medical Outcomes Study . Methods: Cross-sectional study conducted at diabetes referral center a university hospital. Participants were recruited among aged 60 years or older, May 2013 November 2014. The [...]
To evaluate elderly patients in a geriatric service, along with their sensory characteristics and association clinical aspects.This was descriptive longitudinal study. We enrolled 36 healthy participants of both sexes this The following instruments were used evaluations performed: evaluation, Mini-Mental State Exam, quantitative testing.During the follow-up, there reduction mean corpuscular volume at each evaluation (p < 0.001) significant increase hemoglobin concentration 0.001). There an...
Subjective cognitive decline (SCD) is defined as a self-perception of progressive impairment, which not detected objectively through neuropsychological tests. The Alzheimer's Disease Cooperative Study developed the Cognitive Function Instrument (CFI) to evaluate individuals with SCD. CFI consists two versions, namely, self-report and partner report.This study aimed translate into Brazilian Portuguese, perform cross-cultural adaptation, validate version.The translation transcultural...
The great impact that the depression syndrome causes in cognition has already been described. However, some questions like persistence of cognitive dysfunction after remission and deficits influence on treatment response are not completely understood yet. A neuropsychological battery was administered to 87 elderly subjects (> 60 years), from both genders; 42 who met Diagnostic Statistical Manual-IV (DSM-IV) criteria for depressive disorders, based a diagnostic interview by trained...
Cognitive deficits and structural brain alterations are usually found in depressed elderly. The objective of this study was to compare the volume hippocampus parahippocampal gyrus elderly individuals with without depressive disorders, attempting determine whether volumes these regions correlate scores on memory tests. Clinical demographic differences, as well differences total matter volume, were assessed 48 patients disorders 31 control patients. Brain (structural MRI) scans processed using...