A5057766896- Drug-Induced Hepatotoxicity and Protection
- Medicinal Plants and Neuroprotection
- Pharmacological Effects of Natural Compounds
- Alzheimer's disease research and treatments
- Alkaloids: synthesis and pharmacology
- Berberine and alkaloids research
- Biochemical effects in animals
- Cholinesterase and Neurodegenerative Diseases
- Aluminum toxicity and tolerance in plants and animals
- Molecular Sensors and Ion Detection
- Retinoids in leukemia and cellular processes
- Luminescence and Fluorescent Materials
- Endoplasmic Reticulum Stress and Disease
- Pesticide Exposure and Toxicity
- Neuroinflammation and Neurodegeneration Mechanisms
- Nigella sativa pharmacological applications
- Natural Antidiabetic Agents Studies
- Neurological Disease Mechanisms and Treatments
- Natural product bioactivities and synthesis
- Carbon and Quantum Dots Applications
- Retinal Diseases and Treatments
- Neuroscience and Neuropharmacology Research
Shri Vile Parle Kelavani Mandal
2023-2024
Charotar University of Science and Technology
2024
Sankalchand Patel University
2024
Datta Meghe Institute of Medical Sciences
2011-2019
Alzheimer's disease (AD) is a long-term neurodegenerative condition characterized by impaired cognitive functions, particularly in the domains of learning and memory. Finding promising options for AD can be successful with medication repurposing strategy. The goal research was to examine neuroprotective characteristics barbaloin aluminum chloride (AlCl3)-induced deficits changes rats through modulation oxidative stress, cytokines, brain-derived neurotrophic factor (BDNF) expression. Thirty...
We designed a highly sensitive fluorescent sensor for the early detection of sarcosine, potential biomarker prostate cancer. This was based on surface-cobalt-doped carbon quantum dots (Co-CD) using FRET-based photoluminescent sensing platform. Blue luminescent (CQD) were synthesised through hydrothermal approach, utilizing Delonix regia tree pod shells. Cobalt employed to functionalize CQD, enhancing quantum-entrapped effects and minimizing surface flaws. To optimize Co-CD preparation, we...
Streptozotocin (STZ) impairs memory in rats through altering the central nervous systems (CNS) as a result of impaired cholinergic dysfunction, oxidative stress, persistent hyperglycemia, and alterations glucagon-like peptide (GLP). In this model agonist, antioxidant antihyperglycemic treatment has been shown to have positive effects. Barbaloin variety pharmacological However, there is no evidence on how barbaloin improves dysfunction caused by STZ. Thus, we examined its effectiveness...
The theme of the present work is to evaluate protective effect nanoencapsulated quercetin (NEQ) against chlorpyrifos (CPF)-induced hepatic damage and immune alterations in animals. Nanoparticles (NP) drug encapsulation was prepared. Forty male Wistar rats were divided into eight groups. Two groups served as control CPF (13.5 mg/kg) treatment for 28 days. Other three free (QC), NP NEQ treated with 3 mg/kg respectively 15 days; whereas remaining received QC, NP, NEQ, respectively, results show...
Ethanol-induced memory impairment in rats is a consequence of changes within the central nervous system that are secondary to impaired oxidative stress and cholinergic dysfunction.Treatment with antioxidants agonists reported produce beneficial effects animal models.Rutin exhibit antioxidant effect cholinesterase (ChE) inhibitor activity.However, no report available on influence rutin ethanol-induced impairment.Therefore, we tested its against cognitive dysfunction using Morris water maze...