Purslane (Portulaca oleracea L.) is rich in phenolic compounds, protein, and iron. This study aims to produce functional yogurt with enhanced antioxidant, anticancer, antiviral, antimicrobial properties by including safe purslane extract formulation; the was preserved for 30 days at 4 °C, then biochemical fluctuations were monitored. The (PuE) had high compounds flavonoids of 250 56 mg/mL, respectively. Therefore, PuE considerable antioxidant activity, which scavenged 93% DPPH˙, inhibited...

In the present study, an attempt was made to investigate in vitro antioxidant, anticancer, and antibacterial activities of Delonix regia, then vivo evaluate its safety as a natural colorant sweetener beverages compared synthetic rats, serve for sensory evaluation. regia flowers had high protein, polysaccharide, Ca, Na, Mg, K, Fe contents. The pigment extract (DRPE) polysaccharides were separated purified by gel permeation chromatography on Sephacryl S-200, characterized rich (13.6 g/L). HPLC...

The food sector generates massive amounts of waste, which are rich in active compounds, especially polyphenols; therefore, valorizing these wastes is a global trend. In this study, we produce silver nanoparticles from pomegranate wastes, characterized by enhanced antioxidant, anticancer, antiviral, and antimicrobial properties investigated their potential to maintain the fruit quality for sixty days market. waste-mediated (PPAgNPs) were spherical shape (measured TEM), 20 nm (Zeta sizer),...

A participant of the chemical family recognized as anthocyanins, hirsutidin is an O-methylated anthocyanidin. It a natural substance, i.e., existing in Catharanthus roseus (Madagascar periwinkle), predominant component petals, well callus cultures. The literature review indicated lack scientifically verified findings on hirsutidin's biological activities, particularly its anti-Parkinson's capabilities. Using information from previous section reference, present study has been assessed to...

Background: Previously reported data suggest that hibiscetin, isolated from roselle, contains delphinidin-3-sambubioside and cyanidin-3-sambubioside including anthocyanidins has a broad range of physiological effects. In this study, we aim to analyze the effect hibiscetin neuroprotective ability in rats against 3-nitropropionic acid (3-NPA)-induced Huntington’s disease (HD). Methods: To investigate possible toxicities animals, oral acute toxicity studies were undertaken, results revealed...

The examination was sighted to study the preventive effects of rosinidin against rotenone-activated Parkinson's disease in rats.Animals were randamoized into five groups: I-saline, II-rotenone (0.5 mg/kg/b.wt.), III- IV-10 and 20 mg/kg after rotenone V-20 per se for 28 days assigned behavioral analysis., Biochemical parameters i.e. lipid peroxidation, endogenous antioxidants, nitrite level, neurotransmitter levels, proinflammatory biomarkers such as interleukin- 6 (IL-6), tumor necrosis...

Rheumatoid arthritis causes irreparable damage to joints. The present research sought check fustin’s anti-arthritic efficacy against the complete Freund’s adjuvant-induced paradigm in animals by altering inflammatory response. In rats, adjuvant was used trigger and they received fustin at 50 100 mg/kg for 21 days. At regular intervals, hind paw volume arthritic score were assessed. After trial period, hematological, antioxidant, pro-inflammatory cytokines, other biochemical parameters...

Hepatitis E virus (HEV) is one of the leading acute liver infections triggered by viral hepatitis. Patients infected with HEV usually recover and annual death rate negligible. Currently, there no licensed vaccine available globally. This study was carried out to design a multi-epitope peptide-based retrieving already experimentally validated epitopes from ViPR database epitope prioritization. Epitopes selected as potential candidates were non-allergen, immunogenic, soluble, non-toxic IFN...

Anxiety and depression are common psychiatric disorders that affect millions of people worldwide. Lipopolysaccharide (LPS) is a bacterial endotoxin has been demonstrated to cause anxiety-like behaviors in animal models. Fustin flavonoid found various plant species have reported neuroprotective effects. The study proposed the evaluation fustin's impact on anxiety LPS-injected rats.

This study was conducted to evaluate how sterubin affects rotenone-induced Parkinson's disease (PD) in rats. A total of 24 rats were distributed into 4 equal groups: normal saline control and rotenone administered or (ROT), respectively, orally; 10 received ROT + mg/kg po; alone the test group (10 mg/kg). Rats groups sunflower oil injection (sc) daily, 1 h after receiving treatments cited above, while other (0.5 mg/kg, sc). The treatment continued over course 28 days daily. On 29th day,...

Atopic dermatitis (AD) is a type of chronic inflammatory disorder that affects children.

Streptozotocin (STZ) impairs memory in rats through altering the central nervous systems (CNS) as a result of impaired cholinergic dysfunction, oxidative stress, persistent hyperglycemia, and alterations glucagon-like peptide (GLP). In this model agonist, antioxidant antihyperglycemic treatment has been shown to have positive effects. Barbaloin variety pharmacological However, there is no evidence on how barbaloin improves dysfunction caused by STZ. Thus, we examined its effectiveness...

Background: Type 2 diabetes mellitus (T2DM) is common with obesity. Metformin a first-line therapy for this condition. However, it has only minor impact on weight loss in some patients. Aim: This study aimed to evaluate the effectiveness, tolerability, and safety of combining montelukast metformin obese diabetic Methods: One hundred adult patients were recruited randomized into two equal groups. Group 1 received placebo plus g/d, g/d 10 mg/d montelukast. Demographic, anthropometric...

The current study was designed for the evaluation of barbigerone on memory loss. In this experimental study, 24 Wistar rats ( n = 6) were used. Control and scopolamine (SCOP)-treated control group orally administered with 3 ml 0.5% sodium carboxymethyl cellulose (vehicle), whereas (10 20 mg kg −1 ) to from test group. During 14-day treatment, given day saline, all other groups SCOP (1 , i.p.) 1 h after p.o. treatment. spontaneous alternation activities, learning capacities a rat's tested...

The effect of europinidin on alcoholic liver damage in rats was examined this research.A total 24 Wistar were grouped the same way into four groups: normal control (normal), ethanol (EtOH), low dose (10 mg/kg), and higher (20 mg/kg). test group orally treated with europinidin-10 europinidin-20 for 4 weeks, whereas 5 mL/kg distilled water administered to rats. In addition, 1 h after last above-mentioned oral treatment, (i.p.) EtOH injected induce injury. After samples blood withdrawn...

This work investigated the antioxidant and hepatoprotective activities of lemongrass extract its effects on rat hepatotoxicity. The (LGE) contains bioactive components such as phenolic acids, flavonoid components, vitamin C, fibers, tannins. LGE had high content (397 mg/100g) flavonoids (164 mg/100g), influencing activity 91.25%. Additionally, it inhibited 81% breast cancer, also, growth pathogenic bacteria Candida at a concentration 20-40 µg/mL. SARS-Cov-2 by 75%; however, increasing Cas-3....

The research was undertaken to assess the antidiabetic activity of rosiridin in streptozotocin (STZ)-induced diabetic model. Type 2 diabetes mellitus elicited chemically experimental animals using STZ (60 mg/kg, i.p.). Experimental rats were arbitrarily allocated normal control, perse, and + groups. After confirmation diabetes, (10 mg/kg) given orally for 30 days. Various anti-diabetic (blood glucose, insulin), hypolipidemic, anti-inflammatory (Nuclear factor kappa B, tumour necrosis...

The cytokine storm induced by duck hepatitis A virus type 1 (DHAV-1) infection significantly contributes to severe, rapid deaths and economic losses in the industry Egypt. This study aimed investigate potential inhibitory effect of a nano-emulsion containing turmeric black pepper oil on immune response pathogenesis DHAV-1 ducklings. total 105 ducklings from non-vaccinated breeders were divided into 5 experimental groups, each comprising 21 birds. negative control group (G1) remained...

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Abstract Erucic acid is a single unsaturated fatty that falls under the omega‐9 family. It was suggested to treat Wistar rats with lipopolysaccharide (LPS)‐induced memory impairment and minimize cognitive impairment. A total of 30 animals were randomized: group I normally treated group, II administered LPS, III LPS along erucic at dose 10 mg kg –1 p.o. , IV 20 V per se provided se. Behavioral tests evaluated by using Morris water maze Y‐maze. Biochemical analysis including acetylcholine...

Radiation therapy is crucial in cancer treatment, yet access remains limited due to inadequate infrastructure and workforce shortages. The integration of artificial intelligence (AI) radiological workflows holds the potential enhance efficiency improve patient outcomes.This review analyzes current landscape AI applications radiation oncology, focusing on various stages treatment process, including decision-making, planning, quality assurance. We evaluated capabilities techniques,...